{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T19:11:48Z","timestamp":1791054708111,"version":"4.1.0"},"reference-count":39,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T00:00:00Z","timestamp":1466553600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Carlos III Health Institute","doi-asserted-by":"crossref","award":["FIS PI10\/02749-02764"],"award-info":[{"award-number":["FIS PI10\/02749-02764"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004587","name":"Carlos III Health Institute","doi-asserted-by":"crossref","award":["PN I+D+I 2008-2011"],"award-info":[{"award-number":["PN I+D+I 2008-2011"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Education Ministry, Madrid, Spanish Government","award":["FPU AP2010-6075"],"award-info":[{"award-number":["FPU AP2010-6075"]}]},{"name":"Andalusian Health Service, Junta de Andaluc\u00eda","award":["PI-0457-2010"],"award-info":[{"award-number":["PI-0457-2010"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2016,10,15]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND<\/jats:title>\n                    <jats:p>The chronicity status of breast cancer survivors suggests a growing need for cancer rehabilitation. Currently, the use of technology is a promising strategy for providing support, as reflected in the emergence of research interest in Web\u2010based interventions in cancer survivorship.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A randomized controlled trial was conducted that included a total of 81 participants who had completed adjuvant therapy (except hormone treatment) for stage I to IIIA breast cancer. Participants were randomly assigned to an 8\u2010week Internet\u2010based, tailored exercise program (n = 40) or to a control group (n = 41).The instruments used at baseline, 8 weeks, and 6\u2010month follow\u2010up were the European Organization for Research and Treatment of Cancer Quality\u2010of\u2010Life Questionnaire Core 30 and its breast cancer module, the Brief Pain Inventory, the handgrip dynamometer, the isometric abdominal test, the back dynamometer, the multiple sit\u2010to\u2010stand test, and the Piper Fatigue Scale.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      After the intervention, the telerehabilitation group had significantly improved scores for global health status, physical, role, cognitive functioning, and arm symptoms (all\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .01) as well as pain severity (\n                      <jats:italic>P<\/jats:italic>\n                      = .001) and pain interference (\n                      <jats:italic>P<\/jats:italic>\n                      = .045) compared with the control group. Significant improvements also were observed favoring the telerehabilitation group for affected and nonaffected side handgrip (both\n                      <jats:italic>P<\/jats:italic>\n                      = .006), abdominal, back and lower body strength (all\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .01), and total fatigue (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001). These findings were maintained after 6 months of follow\u2010up, except for role functioning, pain severity, and nonaffected side handgrip. Analysis was based on an intention\u2010to\u2010treat principle.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>\n                      This program may improve adverse effects and maintain benefits in breast cancer survivors. The results of this study have encouraging implications for cancer care.\n                      <jats:bold>\n                        <jats:italic>Cancer<\/jats:italic>\n                        2016;122:3166\u201374\n                      <\/jats:bold>\n                      . \u00a9\n                      <jats:italic>2016 American Cancer Society<\/jats:italic>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.30172","type":"journal-article","created":{"date-parts":[[2016,6,23]],"date-time":"2016-06-23T19:01:21Z","timestamp":1466708481000},"page":"3166-3174","source":"Crossref","is-referenced-by-count":326,"title":["Telehealth system: A randomized controlled trial evaluating the impact of an internet\u2010based exercise intervention on quality of life, pain, muscle strength, and fatigue in breast cancer survivors"],"prefix":"10.1002","volume":"122","author":[{"given":"Noelia","family":"Galiano\u2010Castillo","sequence":"first","affiliation":[{"name":"Granada Institute for Biomedical Research University Hospital Complex of Granada\/University of Granada Granada Spain"},{"name":"Department of Physical Therapy University of Granada Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene","family":"Cantarero\u2010Villanueva","sequence":"additional","affiliation":[{"name":"Granada Institute for Biomedical Research University Hospital Complex of Granada\/University of Granada Granada Spain"},{"name":"Department of Physical Therapy University of Granada Granada Spain"},{"name":"Mixed University Sport and Health Institute Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Fern\u00e1ndez\u2010Lao","sequence":"additional","affiliation":[{"name":"Granada Institute for Biomedical Research University Hospital Complex of Granada\/University of Granada Granada Spain"},{"name":"Department of Physical Therapy University of Granada Granada Spain"},{"name":"Mixed University Sport and Health Institute Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lica","family":"Ariza\u2010Garc\u00eda","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy University of Granada Granada Spain"},{"name":"Department of Physical Medicine and Rehabilitation University Hospital San Cecilio Granada Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lourdes","family":"D\u00edaz\u2010Rodr\u00edguez","sequence":"additional","affiliation":[{"name":"Granada Institute for Biomedical Research University Hospital Complex of Granada\/University of Granada Granada Spain"},{"name":"Mixed University Sport and Health Institute Granada Spain"},{"name":"Department of Nursing University of Granada Granada 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