{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T13:24:34Z","timestamp":1788009874915,"version":"build-2784847793"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T00:00:00Z","timestamp":1475193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Incyte Corporation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>This analysis of the myeloproliferative neoplasm (MPN) Landmark survey evaluated gaps between patient perceptions of their disease management and physician self\u2010reported practices.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>The survey included 813 patient respondents who had MPNs (myelofibrosis [MF], polycythemia vera [PV], or essential thrombocythemia [ET]) and 457 hematologist\/oncologist respondents who treated patients with these conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Greater proportions of physician respondents reported using prognostic risk classifications (MF, 83%; PV, 59%; ET, 77%) compared with patient recollections (MF, 54%; PV, 17%; ET, 31%). Most physician respondents reported that their typical symptom assessments included asking patients about the most important symptoms or a full list of symptoms, whereas many patient respondents reported less specific assessments (eg, they were asked how they were feeling). Many patient respondents did not recognize common symptoms as MPN\u2010related. For example, approximately one\u2010half or more did not believe difficulty sleeping resulted from their MPN (MF, 49%; PV, 64%; ET, 76%). Physician respondents underestimated the proportion of patients who had symptomatic PV or ET at diagnosis compared with patient respondents. There was discordance regarding treatment goals: among patient respondents with MF or PV, \u201cslow\/delay progression of condition\u201d was the most important treatment goal, whereas physician respondents reported \u201csymptom improvement\u201d and \u201cprevention of vascular\/thrombotic events,\u201d respectively. Finally, more than one\u2010third of patient respondents were not \u201cvery satisfied\u201d with their physician's overall management\/communication.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>The care and satisfaction of patients with MPN may be improved with increased patient education and improved patient\u2010physician communication. <jats:bold><jats:italic>Cancer<\/jats:italic> 2017;123:449\u2013458.<\/jats:bold> \u00a9 2016 The Authors. <jats:italic>Cancer<\/jats:italic> published by Wiley Periodicals, Inc. on behalf of <jats:italic>American Cancer Society<\/jats:italic>.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.30325","type":"journal-article","created":{"date-parts":[[2016,10,7]],"date-time":"2016-10-07T04:57:56Z","timestamp":1475816276000},"page":"449-458","source":"Crossref","is-referenced-by-count":86,"title":["Differences in treatment goals and perception of symptom burden between patients with myeloproliferative neoplasms (MPNs) and hematologists\/oncologists in the United States: Findings from the MPN Landmark survey"],"prefix":"10.1002","volume":"123","author":[{"given":"Ruben A.","family":"Mesa","sequence":"first","affiliation":[{"name":"Division of Hematology and Medical Oncology Mayo Clinic Cancer Center Scottsdale Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole B.","family":"Miller","sequence":"additional","affiliation":[{"name":"Departments of Internal Medicine and Medical Oncology St Agnes Hospital Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Thyne","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Medical Oncology Weill Cornell Medical College New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Mangan","sequence":"additional","affiliation":[{"name":"Division of Hematology\u2010Oncology University of Pennsylvania Philadelphia Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Goldberger","sequence":"additional","affiliation":[{"name":"Cancer Support Community, Program Development &amp; Delivery New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salman","family":"Fazal","sequence":"additional","affiliation":[{"name":"Division of Hematology and Cellular Therapy Allegheny Health Network Pittsburgh Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomei","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Chronic Disease Epidemiology Yale School of Public Health New Haven Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wendy","family":"Wilson","sequence":"additional","affiliation":[{"name":"Division of Clinical Research Fred Hutchinson Cancer Research Center Seattle Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilan C.","family":"Paranagama","sequence":"additional","affiliation":[{"name":"Global Medical Affairs, Statistics Incyte Corporation Wilmington Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"Dubinski","sequence":"additional","affiliation":[{"name":"US Medical Affairs Incyte Corporation Wilmington Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Naim","sequence":"additional","affiliation":[{"name":"US Medical Affairs Incyte Corporation Wilmington Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shreekant","family":"Parasuraman","sequence":"additional","affiliation":[{"name":"US Medical Affairs Incyte Corporation Wilmington Delaware"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Boyle","sequence":"additional","affiliation":[{"name":"Department of Survey Research ICF International Fairfax 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