{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:22:10Z","timestamp":1784053330674,"version":"3.55.0"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T00:00:00Z","timestamp":1509926400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>BACKGROUND<\/jats:title><jats:p>Human papillomavirus (HPV) vaccines can potentially prevent greater than 90% of cervical and anal cancers as well as a substantial proportion of vulvar, vaginal, penile, and oropharyngeal cancers caused by certain HPV types. Because more than 38,000 HPV\u2010associated cancers are diagnosed annually in the United States, current studies are needed to understand how relative survival varies for each of these cancers by certain demographic characteristics, such as race and age.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>The authors examined high\u2010quality data from 27 population\u2010based cancer registries covering approximately 59% of the US population. The analyses were limited to invasive cancers that were diagnosed during 2001 through 2011 and followed through 2011 and met specified histologic criteria for HPV\u2010associated cancers. Five\u2010year relative survival was calculated from diagnosis until death for these cancers by age, race, and sex.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>The 5\u2010year age\u2010standardized relative survival rate was 64.2% for cervical carcinomas, 52.8% for vaginal squamous cell carcinomas (SCCs), 66% for vulvar SCCs, 47.4% for penile SCCs, 65.9% for anal SCCs, 56.2% for rectal SCCs, and 51.2% for oropharyngeal SCCs. Five\u2010year relative survival was consistently higher among white patients compared with black patients for all HPV\u2010associated cancers across all age groups; the greatest differences by race were observed for oropharyngeal SCCs among those aged &lt;60 years and for penile SCCs among those ages 40 to 49 years compared with other age groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>There are large disparities in relative survival among patients with HPV\u2010associated cancers by sex, race, and age. HPV vaccination and improved access to screening (of cancers for which screening tests are available) and treatment, especially among groups that experience higher incidence and lower survival, may reduce disparities in survival from HPV\u2010associated cancers. <jats:bold><jats:italic>Cancer<\/jats:italic> 2018;124:203\u2010211.<\/jats:bold> Published 2017. This article is a U.S. Government work and is in the public domain in the USA.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.30947","type":"journal-article","created":{"date-parts":[[2017,11,6]],"date-time":"2017-11-06T00:02:46Z","timestamp":1509926566000},"page":"203-211","source":"Crossref","is-referenced-by-count":59,"title":["Five\u2010year relative survival for human papillomavirus\u2010associated cancer sites"],"prefix":"10.1002","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8053-9748","authenticated-orcid":false,"given":"Hilda","family":"Razzaghi","sequence":"first","affiliation":[{"name":"National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention Atlanta Georgia"},{"name":"Epidemic Intelligence Service Program, Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Saraiya","sequence":"additional","affiliation":[{"name":"National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trevor D.","family":"Thompson","sequence":"additional","affiliation":[{"name":"National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. Jane","family":"Henley","sequence":"additional","affiliation":[{"name":"National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Viens","sequence":"additional","affiliation":[{"name":"National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3252-9625","authenticated-orcid":false,"given":"Reda","family":"Wilson","sequence":"additional","affiliation":[{"name":"National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,11,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0b013e318286bb53"},{"key":"e_1_2_8_3_1","volume-title":"IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Volume 90: Human Papillomaviruses","author":"International Agency for Research on Cancer (IARC)","year":"2007"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-15-0044"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djv086"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6526a1"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.07.012"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2015.09.005"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx500034c"},{"key":"e_1_2_8_10_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.ss6604a1","article-title":"Surveillance for cancer incidence and mortality\u2014United States, 2013","volume":"66","author":"Singh SD","year":"2017","journal-title":"MMWR Surveill Summ"},{"key":"e_1_2_8_11_1","first-page":"72","article-title":"Relative survival analysis using the Centers for Disease Control and Prevention's National Program of Cancer Registries Surveillance System Data, 2000\u20102007","volume":"41","author":"Wilson R","year":"2014","journal-title":"J Registry Manag"},{"key":"e_1_2_8_12_1","volume-title":"United States Cancer Statistics. 1999\u20102013 Cancer Incidence and Mortality Data","author":"US Cancer Statistics Working Group","year":"2016"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid2005.131311"},{"key":"e_1_2_8_14_1","volume-title":"International Classification of Diseases for Oncology","author":"World Health Organization","year":"2000"},{"key":"e_1_2_8_15_1","volume-title":"American Joint Commitee on Cancer (AJCC) Cancer Staging Manual","author":"Edge S","year":"2010"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.1713"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23758"},{"key":"e_1_2_8_18_1","first-page":"S10","article-title":"Defining the HPV\u2010associated cancer burden in the United States","volume":"20","author":"Viens L","year":"2016","journal-title":"J Lower Genital Tract Dis"},{"key":"e_1_2_8_19_1","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/QAD.0000000000000873","article-title":"Rectal squamous cell carcinoma in immunosuppressed populations: is this a distinct entity from anal cancer?","volume":"30","author":"Coghill AE","year":"2016","journal-title":"AIDS"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.2006.01677.x"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.07.002"},{"key":"e_1_2_8_22_1","volume-title":"SEER*Stat software. Version 8.3.2","author":"Surveillance Research Program, National Cancer Institute","year":"2016"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2010.246"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djn011"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.26500"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr006"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-9378-5-4"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28250"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2015.5585"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.07.012"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23744"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.36.4596"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2012.06.019"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djn025"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23743"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20519"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20141"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6603a1"},{"issue":"05","key":"e_1_2_8_39_1","first-page":"1","article-title":"Human papillomavirus vaccination: recommendations of the Advisory Committee on Immunization Practices (ACIP)","volume":"63","author":"Markowitz LE","year":"2014","journal-title":"MMWR Recomm Rep."},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0912217"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010815)92:4<805::AID-CNCR1386>3.0.CO;2-9"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.2904"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21389"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28509"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcncr.30947","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.30947","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T17:18:27Z","timestamp":1760289507000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.30947"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,6]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1]]}},"alternative-id":["10.1002\/cncr.30947"],"URL":"https:\/\/doi.org\/10.1002\/cncr.30947","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,6]]}}}