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questions remain about the optimal timing. This study analyzed long\u2010term outcomes and associated factors among recipients of allo\u2010HCT with FL.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Patients with relapsed FL who underwent allo\u2010HCT from 2001 to 2011 with a human leukocyte antigen (HLA)\u2013matched donor were included. Outcome analyses for overall survival (OS), progression\u2010free survival (PFS), transplant\u2010related mortality (TRM), and disease relapse\/progression were calculated. A multivariate analysis was performed to determine factors associated with outcomes, and a prognostic score for treatment failure was developed in a subset analysis of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>In all, 1567 patients with relapsed FL were included; the median follow\u2010up was 55 months. The 5\u2010year probabilities of OS and PFS were 61% and 52%, respectively. The 5\u2010year cumulative incidences of disease progression\/relapse and TRM were 29% and 19%, respectively. Chemoresistant disease, older age, heavy pretreatment, poor performance status (PS), and myeloablative protocols were predictors for worse survival. The prognostic score, using age, lines of prior therapy, disease status, and PS, stratified patients into 3 groups\u2014low, intermediate, and high risk\u2014with 5\u2010year PFS rates of 68%, 53%, and 46%, respectively, and 5\u2010year OS rates of 80%, 62%, and 50%, respectively.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Allo\u2010HCT should be considered for patients with relapsed FL and available HLA\u2010matched donors. Outcomes are better in earlier phases of the disease, and reduced\u2010intensity conditioning should be preferred. The prognostic score presented here can assist in counseling patients and determining the time to proceed to transplantation. <jats:bold><jats:italic>Cancer<\/jats:italic> 2018;124:1733\u201342<\/jats:bold>. \u00a9 <jats:italic>2018 American Cancer Society<\/jats:italic><\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.31264","type":"journal-article","created":{"date-parts":[[2018,2,9]],"date-time":"2018-02-09T10:09:00Z","timestamp":1518170940000},"page":"1733-1742","source":"Crossref","is-referenced-by-count":71,"title":["Allogeneic hematopoietic stem cell transplantation for relapsed follicular lymphoma: A combined analysis on behalf of the Lymphoma Working Party of the EBMT and the Lymphoma Committee of the CIBMTR"],"prefix":"10.1002","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1238-6970","authenticated-orcid":false,"given":"Anna","family":"Sureda","sequence":"first","affiliation":[{"name":"Hematology Department Institut Catal\u00e0 d'Oncologia\u2013Hospitalet Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei\u2010Jie","family":"Zhang","sequence":"additional","affiliation":[{"name":"Center for International Blood and Marrow Transplant Research, Department of Medicine Medical College of Wisconsin Milwaukee Wisconsin"},{"name":"Division of Biostatistics, Institute for Health and Society Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Dreger","sequence":"additional","affiliation":[{"name":"Universitaetsklinkum Heidelberg Heidelberg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeanette","family":"Carreras","sequence":"additional","affiliation":[{"name":"Center for International Blood and Marrow Transplant Research, Department of Medicine Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Fenske","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology, Department of Medicine Medical College of Wisconsin Milwaukee Wisconsin"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herve","family":"Finel","sequence":"additional","affiliation":[{"name":"Central Registry Office European Society for Blood and Marrow Transplantation Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Schouten","sequence":"additional","affiliation":[{"name":"Department of Hematology Academische Ziekenhuis Maastricht the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Montoto","sequence":"additional","affiliation":[{"name":"Department of Haemato\u2010Oncology, St. Bartholomew's Hospital Barts Health NHS Trust London United 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