{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T15:13:40Z","timestamp":1781104420600,"version":"3.54.1"},"reference-count":38,"publisher":"Wiley","issue":"21","license":[{"start":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T00:00:00Z","timestamp":1536883200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["TR001862"],"award-info":[{"award-number":["TR001862"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["Yale Cancer Center Pilot Grant"],"award-info":[{"award-number":["Yale Cancer Center Pilot Grant"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010900","name":"Yale Cancer Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010900","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Although provider\u2010level volume is frequently associated with outcomes in cancers requiring complex surgeries, whether similar relations exist for cancers treated primarily with systemic therapy is unknown.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Using a population\u2010based cohort analysis of older adults diagnosed with diffuse large B cell lymphoma (DLBCL) during the years 2004\u20102011, we evaluated the association between oncologist volume and 4 clinical outcomes (receipt of any chemotherapy, receipt of an anthracycline\u2010containing or equivalent regimen, early hospitalization, and overall survival). Our primary explanatory variable was lymphoma treatment volume, defined as the number of patients with newly diagnosed lymphoma for which an oncologist initiated therapy during a 12\u2010month look\u2010back period from each incident DLBCL case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 8247 Medicare beneficiaries who were newly diagnosed with DLBCL. Chemotherapy was administered to 6202 (75.2%) beneficiaries, and 71.4% of cytotoxic regimens contained an anthracycline. Beneficiaries who were treated by higher\u2010volume oncologists had increased odds of receiving chemotherapy (adjusted odds ratio [aOR], 1.45; 95% confidence interval [CI], 1.24\u20101.70;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;.001) and of receiving an anthracycline\u2010containing regimen (aOR, 1.26; 95% CI, 1.06\u20101.50;\n                      <jats:italic>P<\/jats:italic>\n                      = .009). Receiving care from a higher\u2010volume provider was also associated with decreased hospitalization (aOR, 0.80; 95% CI, 0.69\u20100.95;\n                      <jats:italic>P<\/jats:italic>\n                      = .007) and improved survival (adjusted hazard ratio, 0.85; 95% CI, 0.79\u20100.92;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; .001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In older adults diagnosed with DLBCL, receiving care from a provider with more experience treating lymphoma patients was associated with receipt of guideline\u2010adherent therapy, reduced hospitalizations, and improved survival. Clinical volume may be an important factor in providing high\u2010quality cancer care in the modern era.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.31688","type":"journal-article","created":{"date-parts":[[2018,9,16]],"date-time":"2018-09-16T06:08:37Z","timestamp":1537078117000},"page":"4211-4220","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Oncologist volume and outcomes in older adults diagnosed with diffuse large B cell lymphoma"],"prefix":"10.1002","volume":"124","author":[{"given":"Scott F.","family":"Huntington","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Section of Hematology Yale University New Haven, Connecticut"},{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale University New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica R.","family":"Hoag","sequence":"additional","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale University New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Zhu","sequence":"additional","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale University New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2169-4174","authenticated-orcid":false,"given":"Rong","family":"Wang","sequence":"additional","affiliation":[{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale University New Haven, Connecticut"},{"name":"Department of Chronic Disease Epidemiology Yale School of Public Health New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer M.","family":"Zeidan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Section of Hematology Yale University New Haven, Connecticut"},{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale University New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smith","family":"Giri","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Section of Hematology Yale University New Haven, Connecticut"},{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale University New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolai A.","family":"Podoltsev","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Section of Hematology Yale University New Haven, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven 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