{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:11:11Z","timestamp":1790122271779,"version":"4.0.1"},"reference-count":25,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T00:00:00Z","timestamp":1582588800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100005189","name":"Leukemia and Lymphoma Society","doi-asserted-by":"publisher","award":["62771\u201011"],"award-info":[{"award-number":["62771\u201011"]}],"id":[{"id":"10.13039\/100005189","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2020,5,15]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cognitive impairment in survivors of blood or bone marrow transplantation (BMT) is well documented. However, to the authors' knowledge, the clinical relevance of self\u2010endorsed cognitive problems and their relation to objectively assessed cognitive impairment is not known.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The authors assessed cognitive impairment in 378 BMT recipients (median age, 52.2\u00a0years, 40% of whom were female and 68% of whom were non\u2010Hispanic white) and 98 healthy controls at 5 predetermined time points: at baseline (before BMT) and at 6\u00a0months, 1\u00a0year, 2\u00a0years, and 3\u00a0years after BMT. Self\u2010endorsed cognitive problems were evaluated using the Neuropsychological Impairment Scale (NIS) and correlated with a standardized 2\u2010hour battery of objective cognitive testing at each time point. The authors examined the magnitude of difference in self\u2010endorsed cognitive problems between BMT recipients and healthy controls, and the rate of change in scores over time. Multivariable analyses were used to identify clinical and\/or demographic variables associated with self\u2010endorsed cognitive problems. The authors also examined the association between cognitive impairment and returning to work after BMT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared with healthy controls, BMT recipients endorsed more cognitive problems (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001) at all time points, and the rate of change in NIS scores was found to be significantly greater in BMT recipients. Fatigue was associated with greater endorsement of cognitive problems at 1\u00a0year after BMT (odds ratio, 4.23; 95% CI, 2.1\u20108.3 [\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001]). Overall, there was a statistically significant, modest correlation noted between self\u2010endorsed cognitive problems and objective cognitive impairment (range, 0.401\u20100.445 [\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0\u2264\u00a0.01]). Higher self\u2010endorsed cognitive problems were associated with a 3.7\u2010fold (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a0.02) higher odds of not returning to work at 3\u00a0years after BMT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The results of the current study demonstrated that self\u2010endorsed cognitive problems can help to identify vulnerable patient subpopulations for detailed cognitive assessment and possible cognitive remediation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.32773","type":"journal-article","created":{"date-parts":[[2020,2,25]],"date-time":"2020-02-25T14:19:21Z","timestamp":1582640361000},"page":"2174-2182","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Self\u2010endorsed cognitive problems versus objectively assessed cognitive impairment in blood or bone marrow transplantation recipients: A longitudinal study"],"prefix":"10.1002","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8550-8353","authenticated-orcid":false,"given":"Donna L.","family":"Murdaugh","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of Alabama at Birmingham Birmingham Alabama"},{"name":"Institute for Cancer Outcomes and Survivorship University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0662-5699","authenticated-orcid":false,"given":"Alysia","family":"Bosworth","sequence":"additional","affiliation":[{"name":"Department of Population Sciences City of Hope Duarte California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9023-8391","authenticated-orcid":false,"given":"Sunita K.","family":"Patel","sequence":"additional","affiliation":[{"name":"Department of Population Sciences City of Hope Duarte California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noha","family":"Sharafeldin","sequence":"additional","affiliation":[{"name":"Institute for Cancer Outcomes and Survivorship University of Alabama at Birmingham Birmingham Alabama"},{"name":"Division of Hematology\/Oncology Department of Medicine University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Hematology and Hematopoietic Cell Transplantation City of Hope National Medical Center Duarte California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liton","family":"Francisco","sequence":"additional","affiliation":[{"name":"Institute for Cancer Outcomes and Survivorship University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Forman","sequence":"additional","affiliation":[{"name":"Department of Hematology and Hematopoietic Cell Transplantation City of Hope National Medical Center Duarte California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Lennie","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Population Sciences City of Hope Duarte California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7755-5683","authenticated-orcid":false,"given":"Smita","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Alabama at Birmingham Birmingham Alabama"},{"name":"Institute for Cancer Outcomes and Survivorship University of Alabama at Birmingham Birmingham Alabama"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,2,25]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-03-1155"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.33.9119"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.74.2270"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djt073"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21258"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djt073"},{"key":"e_1_2_8_8_1","volume-title":"The Neuropsychological Impairment Scale","author":"O\u2019Donnell WE","year":"2009"},{"key":"e_1_2_8_9_1","volume-title":"Profile of Mood States: Technical Update","author":"McNair DM","year":"2005"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008842517972"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/00343552040480010801"},{"key":"e_1_2_8_12_1","volume-title":"WRAT 4: Wide Range Achievement Test","author":"Wilkinson GS","year":"2006"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4679(199305)49:3<372::AID-JCLP2270490311>3.0.CO;2-K"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4679(198309)39:5<746::AID-JCLP2270390517>3.0.CO;2-7"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.08.1604"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3159"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2011.06.027"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1067\/mem.2003.77"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2013.02.014"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.3248"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2011.08.011"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2005.10.005"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0953-6205(01)00198-4"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2004.02.029"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/geronb\/58.4.P203"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejon.2012.06.002"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcncr.32773","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.32773","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cncr.32773","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.32773","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T00:46:01Z","timestamp":1761871561000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.32773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2,25]]},"references-count":25,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2020,5,15]]}},"alternative-id":["10.1002\/cncr.32773"],"URL":"https:\/\/doi.org\/10.1002\/cncr.32773","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2,25]]},"assertion":[{"value":"2019-09-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-01-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-02-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}