{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T21:35:39Z","timestamp":1792272939210,"version":"4.4.0"},"reference-count":65,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T00:00:00Z","timestamp":1583971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000130","name":"National Center for Chronic Disease Prevention and Health Promotion","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000048","name":"American Cancer Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000030","name":"Centers for Disease Control and Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000030","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2020,5,15]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The American Cancer Society, the Centers for Disease Control and Prevention, the National Cancer Institute, and the North American Association of Central Cancer Registries collaborate to provide annual updates on cancer occurrence and trends in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data on new cancer diagnoses during 2001 through 2016 were obtained from the Centers for Disease Control and Prevention\u2010funded and National Cancer Institute\u2010funded population\u2010based cancer registry programs and compiled by the North American Association of Central Cancer Registries. Data on cancer deaths during 2001 through 2017 were obtained from the National Center for Health Statistics' National Vital Statistics System. Trends in incidence and death rates for all cancers combined and for the leading cancer types by sex, racial\/ethnic group, and age were estimated by joinpoint analysis and characterized by the average annual percent change during the most recent 5\u00a0years (2012\u20102016 for incidence and 2013\u20102017 for mortality).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, cancer incidence rates decreased 0.6% on average per year during 2012 through 2016, but trends differed by sex, racial\/ethnic group, and cancer type. Among males, cancer incidence rates were stable overall and among non\u2010Hispanic white males but decreased in other racial\/ethnic groups; rates increased for 5 of the 17 most common cancers, were stable for 7 cancers (including prostate), and decreased for 5 cancers (including lung and bronchus [lung] and colorectal). Among females, cancer incidence rates increased during 2012 to 2016 in all racial\/ethnic groups, increasing on average 0.2% per year; rates increased for 8 of the 18 most common cancers (including breast), were stable for 6 cancers (including colorectal), and decreased for 4 cancers (including lung). Overall, cancer death rates decreased 1.5% on average per year during 2013 to 2017, decreasing 1.8% per year among males and 1.4% per year among females. During 2013 to 2017, cancer death rates decreased for all cancers combined among both males and females in each racial\/ethnic group, for 11 of the 19 most common cancers among males (including lung and colorectal), and for 14 of the 20 most common cancers among females (including lung, colorectal, and breast). The largest declines in death rates were observed for melanoma of the skin (decreasing 6.1% per year among males and 6.3% among females) and lung (decreasing 4.8% per year among males and 3.7% among females). Among children younger than 15\u00a0years, cancer incidence rates increased an average of 0.8% per year during 2012 to 2016, and cancer death rates decreased an average of 1.4% per year during 2013 to 2017. Among adolescents and young adults aged 15 to 39\u00a0years, cancer incidence rates increased an average of 0.9% per year during 2012 to 2016, and cancer death rates decreased an average of 1.0% per year during 2013 to 2017.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although overall cancer death rates continue to decline, incidence rates are leveling off among males and are increasing slightly among females. These trends reflect population changes in cancer risk factors, screening test use, diagnostic practices, and treatment advances. Many cancers can be prevented or treated effectively if they are found early. Population\u2010based cancer incidence and mortality data can be used to inform efforts to decrease the cancer burden in the United States and regularly monitor progress toward goals.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.32802","type":"journal-article","created":{"date-parts":[[2020,3,12]],"date-time":"2020-03-12T04:01:30Z","timestamp":1583985690000},"page":"2225-2249","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":668,"title":["Annual report to the nation on the status of cancer, part I: National cancer statistics"],"prefix":"10.1002","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2420-306X","authenticated-orcid":false,"given":"S. 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Rockville Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheryll C.","family":"Thomas","sequence":"additional","affiliation":[{"name":"Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7357-5994","authenticated-orcid":false,"given":"Farhad","family":"Islami","sequence":"additional","affiliation":[{"name":"Surveillance and Health Services Research American Cancer Society Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6568-9708","authenticated-orcid":false,"given":"Hannah K.","family":"Weir","sequence":"additional","affiliation":[{"name":"Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3385-2958","authenticated-orcid":false,"given":"Denise Riedel","family":"Lewis","sequence":"additional","affiliation":[{"name":"Division of Cancer Control and Population Sciences National Cancer Institute National Institutes of Health Bethesda Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Recinda L.","family":"Sherman","sequence":"additional","affiliation":[{"name":"North American Association of Central Cancer Registries Springfield Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manxia","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vicki B.","family":"Benard","sequence":"additional","affiliation":[{"name":"Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa C.","family":"Richardson","sequence":"additional","affiliation":[{"name":"Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion Centers for Disease Control and Prevention Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0000-4111","authenticated-orcid":false,"given":"Ahmedin","family":"Jemal","sequence":"additional","affiliation":[{"name":"Surveillance and Health Services Research American Cancer Society Atlanta Georgia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Cronin","sequence":"additional","affiliation":[{"name":"Division of Cancer Control and Population Sciences National Cancer Institute National Institutes of Health Bethesda Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betsy A.","family":"Kohler","sequence":"additional","affiliation":[{"name":"North American Association of Central Cancer Registries Springfield Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,3,12]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djz106"},{"key":"e_1_2_8_3_1","first-page":"000","article-title":"Annual report to the nation on the status of cancer, part II: progress toward Healthy People 2020 objectives for 4 common cancers","volume":"000","author":"Henley SJ","year":"2020","journal-title":"Cancer"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6254a3"},{"key":"e_1_2_8_5_1","volume-title":"Cancer in North America: 2012\u20102016. 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