{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T03:35:24Z","timestamp":1789011324815,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T00:00:00Z","timestamp":1595548800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006436","name":"Celgene","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006436","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100002491","name":"Bristol-Myers Squibb","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002491","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Studies have reported racial disparities in access to and use of multiple myeloma (MM) treatments between African American (AA) and White patients. Although AA patients demonstrate longer disease\u2010specific survival, this has not uniformly translated into improved survival over time. The association between race and treatment patterns and survival outcomes was analyzed using data from the Connect MM Registry.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The Connect MM Registry is a large US, multicenter, prospective observational cohort study of patients with newly diagnosed MM. Patients who received first\u2010line (1L) stem cell transplantation (SCT) or who did not receive SCT (non\u2010SCT or non\u2013stem cell transplantation [NSCT]) were grouped by raceEffects of race and transplantation status on the use of triplet treatment were estimated using logistic regression.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Treatment patterns in 1L (types and duration of induction, posttransplantation maintenance) were similar between AA and White patients. SCT rates in 1L (32% vs 36%) and triplet treatment use (AA: 44% for NSCT patients and 72% for SCT patients; and White: 48% for NSCT patients and 72% for SCT patients) during first induction were similar. No significant effect of race or transplantation status on 1L triplet treatment use was observed. Race was not found to be associated with survival outcomes among patients who underwent NSCT; however, AA patients who received SCT had significantly longer overall survival compared with White patients who underwent SCT (not reached vs 88.2 months; hazard ratio, 0.56; 95% CI, 0.35\u20100.89 [<jats:italic>P<\/jats:italic>\u00a0=\u00a0.0141]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>AA and White patients were found to have similar treatment patterns in the Connect MM Registry, suggesting that both groups had equal access to health care. In this real\u2010world setting, AA patients received standard\u2010of\u2010care treatment, which might have contributed to better MM\u2010specific survival compared with White patients.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.33089","type":"journal-article","created":{"date-parts":[[2020,7,24]],"date-time":"2020-07-24T10:05:52Z","timestamp":1595585152000},"page":"4332-4340","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Association between race and treatment patterns and survival outcomes in multiple myeloma: A Connect MM Registry analysis"],"prefix":"10.1002","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8377-8111","authenticated-orcid":false,"given":"Sikander","family":"Ailawadhi","sequence":"first","affiliation":[{"name":"Mayo Clinic Jacksonville Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2934-6518","authenticated-orcid":false,"given":"Sundar","family":"Jagannath","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital New York New York"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans C.","family":"Lee","sequence":"additional","affiliation":[{"name":"The University of Texas MD Anderson Cancer Center Houston Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Narang","sequence":"additional","affiliation":[{"name":"US Oncology Research Columbia Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert M.","family":"Rifkin","sequence":"additional","affiliation":[{"name":"Rocky Mountain Cancer Centers US Oncology Research Denver Colorado"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard R.","family":"Terebelo","sequence":"additional","affiliation":[{"name":"Providence Cancer Institute Southfield Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian G. M.","family":"Durie","sequence":"additional","affiliation":[{"name":"Cedars\u2010Sinai Medical Center Los Angeles California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen","family":"Toomey","sequence":"additional","affiliation":[{"name":"Steeplechase Cancer Center Somerville New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James W.","family":"Hardin","sequence":"additional","affiliation":[{"name":"University of South Carolina Columbia South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina J.","family":"Gasparetto","sequence":"additional","affiliation":[{"name":"Duke University Medical Center Durham North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9685-4796","authenticated-orcid":false,"given":"Lynne","family":"Wagner","sequence":"additional","affiliation":[{"name":"Wake Forest School of Medicine Winston\u2010Salem North Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James L.","family":"Omel","sequence":"additional","affiliation":[{"name":"Myeloma Research Advocate\/Advisor Grand Island Nebraska"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mia","family":"He","sequence":"additional","affiliation":[{"name":"Bristol\u2010Myers Squibb Summit New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lihua","family":"Yue","sequence":"additional","affiliation":[{"name":"Bristol\u2010Myers Squibb Summit New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth Dawn","family":"Flick","sequence":"additional","affiliation":[{"name":"Bristol\u2010Myers Squibb Summit New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Bristol\u2010Myers Squibb Summit New Jersey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafat","family":"Abonour","sequence":"additional","affiliation":[{"name":"Indiana University Indianapolis Indiana"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Connect MM Registry 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