{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:41:54Z","timestamp":1760316114629,"version":"build-2065373602"},"reference-count":34,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T00:00:00Z","timestamp":1603929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100013678","name":"Cancer Center, University of Colorado","doi-asserted-by":"publisher","award":["P30CA046934"],"award-info":[{"award-number":["P30CA046934"]}],"id":[{"id":"10.13039\/100013678","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000072","name":"National Institute of Dental and Craniofacial Research","doi-asserted-by":"publisher","award":["R01\u2010DE028282","R01\u2010DE028529"],"award-info":[{"award-number":["R01\u2010DE028282","R01\u2010DE028529"]}],"id":[{"id":"10.13039\/100000072","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2021,2,15]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>Persistent controversy exists with regard to how and when patients with head and neck cancer should undergo imaging after definitive therapy. The current study was conducted to evaluate whether the type of imaging modality used in posttreatment imaging impacts cancer\u2010specific survival for patients with advanced head and neck squamous cell carcinoma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A retrospective study of National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) program\u2013Medicare\u2010linked data in patients with an advanced stage of the 3 most common head and neck malignancies (oral cavity, oropharynx, and larynx) was conducted. Hazard ratios and 95% CIs for cancer\u2010specific survival were estimated for patients diagnosed with any of these cancers between 2006 and 2015.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Significant improvement with regard to cancer\u2010specific survival was observed among patients with American Joint Committee on Cancer stage III and stage IVA laryngeal cancer who underwent positron emission tomography (PET) and\/or computed tomography (CT) imaging during the first 6 months after receipt of definitive treatment (hazard ratio, 0.517; 95% CI, 0.33\u20100.811) compared with those who underwent CT. There was a trend toward an improvement in cancer\u2010specific survival among patients with oral cavity or oropharyngeal malignancies who underwent PET\/CT imaging, but it did not reach statistical significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Compared with CT imaging, posttreatment imaging with PET was associated with improved survival in patients with advanced laryngeal carcinoma.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.33244","type":"journal-article","created":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T10:23:15Z","timestamp":1603966995000},"page":"535-543","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparative effectiveness of posttreatment imaging modalities for Medicare patients with advanced head and neck cancer"],"prefix":"10.1002","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3881-7257","authenticated-orcid":false,"given":"Rustain L.","family":"Morgan","sequence":"first","affiliation":[{"name":"Department of Radiology Anschutz Medical Campus, University of Colorado  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan M.","family":"Eguchi","sequence":"additional","affiliation":[{"name":"University of Colorado Cancer Center, Anschutz Medical Campus, University of Colorado  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica","family":"McDermott","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Anschutz Medical Campus, University of Colorado  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adam C.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Anschutz Medical Campus, University of Colorado  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8311-9159","authenticated-orcid":false,"given":"Arya","family":"Amini","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology City of Hope National Medical Center  Duarte California"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie A.","family":"Goddard","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Anschutz Medical Campus, University of Colorado  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Premal S.","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Department of Radiology Anschutz Medical Campus, University of Colorado  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sana D.","family":"Karam","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Anschutz Medical Campus, University of Colorado  Aurora Colorado"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,10,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21551"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10314"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.25936"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13014-017-0900-2"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-019-05292-0"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0164068"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2018.0026"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26268"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2019.1934"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24032"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(00)00256-0"},{"key":"e_1_2_8_13_1","unstructured":"National Comprehensive Cancer Network.Head and Neck Cancers\u2013Version 2.2018. 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