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The authors sought to evaluate the prevalence of sexual dysfunction in women with lung cancer in our current clinical environment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional survey study was administered online to 249 women via the GO2 for Lung Cancer (GO2) Registry, using the Patient\u2010Reported Outcomes Measurement Information System Sexual Function and Satisfaction Measures questionnaire. Participants were recruited between June 2020 to June 2021. Eligibility criteria included age &gt;18\u00a0years, self\u2010identifying as a woman, fluency in English, and a lung cancer diagnosis within 10 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Most (67%) had stage IV lung cancer and 47% were receiving targeted therapy; 66% were undergoing active treatment. Despite 54% of participants reporting \u201crecent\u201d sexual activity, most (77%) indicated having little to no interest in sexual activity and 48% reported recent minimal satisfaction with their sex life. The most common reasons negatively affecting participants' satisfaction with their sex life included fatigue (40%) and feeling sad\/unhappy (28%). Common reasons for lack of recent sexual activity included lack of interest (68%) and vaginal dryness or pain (30%). Compared to pre\u2010diagnosis, women were significantly less likely to have recent interest in sexual activity. In multivariable logistic\u2010regression, vaginal dryness showed a significant negative association with recent interest in sexual activity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Sexual dysfunction is prevalent in women with lung cancer. Sexual health should be integrated into routine care for patients with lung cancer.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.35057","type":"journal-article","created":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T08:14:40Z","timestamp":1697444080000},"page":"375-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Sexual Health Assessment in Women with Lung Cancer study: Sexual health assessment in women with lung cancer"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-0806-6722","authenticated-orcid":false,"given":"Narjust","family":"Florez","sequence":"first","affiliation":[{"name":"Harvard Medical School  Boston Massachusetts USA"},{"name":"Dana\u2010Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Kiel","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Meza","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihan","family":"Wei","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emanuele","family":"Mazzola","sequence":"additional","affiliation":[{"name":"Dana\u2010Farber Cancer Institute  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6153-5557","authenticated-orcid":false,"given":"Ana I.","family":"Velazquez","sequence":"additional","affiliation":[{"name":"UCSF Helen Diller Family Comprehensive Cancer Center University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Idalid","family":"Franco","sequence":"additional","affiliation":[{"name":"Harvard Medical School  Boston Massachusetts USA"},{"name":"Dana\u2010Farber Cancer Institute  Boston Massachusetts USA"},{"name":"Brigham and Women\u2019s Hospital  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Jo","family":"Fidler","sequence":"additional","affiliation":[{"name":"Rush University Medical Center  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivy","family":"Elkins","sequence":"additional","affiliation":[{"name":"EGFR Resisters  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2107-8240","authenticated-orcid":false,"given":"Jill","family":"Feldman","sequence":"additional","affiliation":[{"name":"EGFR Resisters  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori","family":"Seaborne","sequence":"additional","affiliation":[{"name":"University of Wisconsin  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3698-9231","authenticated-orcid":false,"given":"Christine","family":"Heisler","sequence":"additional","affiliation":[{"name":"University of Wisconsin  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4394-4103","authenticated-orcid":false,"given":"Jennifer C.","family":"King","sequence":"additional","affiliation":[{"name":"GO2 for Lung Cancer  Washington District of Columbia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Moore","sequence":"additional","affiliation":[{"name":"LUNGevity Foundation for Lung Cancer  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacinta","family":"Wiens","sequence":"additional","affiliation":[{"name":"Merck Pharmaceuticals  Rahway New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Kushner","sequence":"additional","affiliation":[{"name":"University of Wisconsin  Madison Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1715907"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2003.11.021"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afi143"},{"key":"e_1_2_9_6_1","unstructured":"Mayo Clinic.Female sexual dysfunction.2022. 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