{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T14:20:40Z","timestamp":1790346040159,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T00:00:00Z","timestamp":1708646400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002999","name":"Ministerie van Volksgezondheid, Welzijn en Sport","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002999","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["VIDI198.007"],"award-info":[{"award-number":["VIDI198.007"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004622","name":"KWF Kankerbestrijding","doi-asserted-by":"publisher","award":["11788"],"award-info":[{"award-number":["11788"]}],"id":[{"id":"10.13039\/501100004622","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of this population\u2010based registry study was to examine the impact of cancer on employment outcomes in adolescent and young adult (AYA) survivors and their partners and associated sociodemographic and clinical characteristics.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 2456 AYA cancer patients, diagnosed in 2013 and aged 18 through 39\u00a0years old, were selected from the Netherlands Cancer Registry and linked to employment data from Statistics Netherlands, from which 1252 partners of AYAs could be identified. For both patients and their partners, a control group with same age, migration background, and sex was selected. The impact (i.e., causal effect) was estimated by implementing a doubly robust difference\u2010in\u2010differences method, from 3\u00a0years before to 5\u00a0years after cancer diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Patients suffered a reduced employment probability (3.8 percentage points) and number of hours worked when employed (3.8%). This effect was larger for females, and individuals with a migration background, high tumor stage, or diagnosed with a central nervous system tumor\/hematologic malignancy. In regard to employment, no significant effect could be found for the patients\u2019 partners, although a 5.5 percentage\u2010point increase in employment probability was found in partners who were either unemployed or worked fewer than 400\u00a0hours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>A cancer diagnosis significantly affects employment outcomes of AYA patients with cancer. Patients at risk should have access to services such as job counseling to help them return into society in the best possible way. No objective impact on partners\u2019 employment outcomes was found; however, subjective well\u2010being was not taken into account.<\/jats:p><\/jats:sec><jats:sec><jats:title>Plain Language Summary<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>This study estimated the causal effect of a cancer diagnosis on employment outcomes.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Adolescent and young adult cancer survivors face a reduction in both employment probability and the number of hours worked when employed.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Partners that were unemployed or worked the least number of hours a year before diagnosis had a 5.5 percentage\u2010point increased employment probability, but for other partners effects are small.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.35260","type":"journal-article","created":{"date-parts":[[2024,2,23]],"date-time":"2024-02-23T21:54:25Z","timestamp":1708725265000},"page":"2372-2383","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Employment outcomes of adolescent and young adult cancer\u00a0survivors and their partners: A Dutch population\u2010based study"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-7659-5296","authenticated-orcid":false,"given":"Polle W.","family":"Dankers","sequence":"first","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute \u2010 Antoni van Leeuwenhoek  Amsterdam The Netherlands"},{"name":"Department of Econometrics and Operations Research Tilburg University  Tilburg The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1406-1739","authenticated-orcid":false,"given":"Silvie H. M.","family":"Janssen","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology Netherlands Cancer Institute \u2010 Antoni van Leeuwenhoek  Amsterdam The Netherlands"},{"name":"Department of Psychosocial Research and Epidemiology Netherlands Cancer Institute  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6731-3296","authenticated-orcid":false,"given":"Mies","family":"van Eenbergen","sequence":"additional","affiliation":[{"name":"Department of Research and Development Netherlands Comprehensive Cancer Organization  Utrecht The Netherlands"},{"name":"Department of Communication and Cognition Tilburg University  Tilburg The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina M.","family":"Siflinger","sequence":"additional","affiliation":[{"name":"Department of Econometrics and Operations Research Tilburg University  Tilburg The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7549-3338","authenticated-orcid":false,"given":"Winette T. 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