{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:09:34Z","timestamp":1790237374704,"version":"4.1.0"},"reference-count":19,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T00:00:00Z","timestamp":1718323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:p>Dual checkpoint blockade with nivolumab plus ipilimumab in patients with advanced, refractory gallbladder cancer showed activity in select patients in cohort 48 of the SWOG 1609 DART trial. Optimizing patient selection for this regimen will require validating predictive biomarkers of response and understanding the role of the regimen after chemoimmunotherapy in the frontline.<\/jats:p>","DOI":"10.1002\/cncr.35352","type":"journal-article","created":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T05:23:28Z","timestamp":1718342608000},"page":"2904-2906","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dual checkpoint inhibition in gallbladder cancer: Bridging new hope with the need for biomarkers"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0102-1789","authenticated-orcid":false,"given":"Fen","family":"Saj","sequence":"first","affiliation":[{"name":"Department of Medical Oncology Balco Medical Center  Raipur Chhattisgarh India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5818-7678","authenticated-orcid":false,"given":"Y. Linda","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology Herbert Irving Comprehensive Cancer Center Columbia University Irving Medical Center  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9281-480X","authenticated-orcid":false,"given":"Shubham","family":"Pant","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Medical Oncology The University of Texas MD Anderson Cancer Center  Houston TX USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9777-6221","authenticated-orcid":false,"given":"Lipika","family":"Goyal","sequence":"additional","affiliation":[{"name":"Division of Oncology Department of Medicine Stanford School of Medicine  Palo Alto CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,14]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572\u2010022\u201000398\u2010y"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i22.3978"},{"key":"e_1_2_4_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/evidoa2200015"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(23)00727\u20104"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/po.22.00573"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1470\u20102045(21)00027\u20109"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1200\/go.20.00657"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2020.2814"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159\u20108290.cd\u201017\u20100245"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1200\/po.21.00510"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201077939\u20106"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1910836"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2023.3295"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591\u2010023\u201002498\u2010y"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388\u2010023\u201002835\u2010y"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc\u20102021\u2010003853"},{"key":"e_1_2_4_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40364\u2010022\u201000378\u20100"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577\u2010023\u201000973\u20108"},{"key":"e_1_2_4_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575\u2010022\u201000741\u20104"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.35352","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T16:01:34Z","timestamp":1760284894000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.35352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,14]]},"references-count":19,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["10.1002\/cncr.35352"],"URL":"https:\/\/doi.org\/10.1002\/cncr.35352","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,6,14]]},"assertion":[{"value":"2024-06-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}