{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:23:27Z","timestamp":1792193007715,"version":"4.4.0"},"reference-count":30,"publisher":"Wiley","issue":"23","license":[{"start":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T00:00:00Z","timestamp":1723593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["CA244172"],"award-info":[{"award-number":["CA244172"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Hematopoietic stem cell transplantation (HCT) is an intensive and invasive procedure used in cancer treatment that can lead to posttraumatic stress disorder (PTSD) symptoms. These symptoms are frequently overlooked in oncology and general health care settings. The suitability and utility of the Primary Care PTSD Screen for DSM\u20105 (PC\u2010PTSD\u20105) within the cancer population remains uncertain. This study aims to evaluate its performance as a brief (five\u2010item) case\u2010finding screening alternative to the longer (20\u2010item) PTSD Checklist for DSM\u20105 (PCL\u20105) in survivors who received an HCT 1 to 5 years ago.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 817 cancer survivors completed the PC\u2010PTSD\u20105 and PCL\u20105 during recruitment for a randomized clinical trial. Optimal cut scores for identifying probable PTSD and item performance were determined using indices correcting for chance and item response theory analyses.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of the HCT sample, 25.7% screened as positive for probable DSM\u20105 PTSD using the PCL\u20105. The PC\u2010PTSD\u20105 exhibited strong internal consistency and significant associations with PCL\u20105 scores (total, <jats:italic>r<\/jats:italic>\u00a0=\u00a0.82; items, <jats:italic>r<\/jats:italic>s\u00a0=\u00a0.56\u2013.61). A cutoff score of 2 provided optimal sensitivity for screening (\u03ba[Se]\u00a0=\u00a0.94), whereas a cut score of 4 demonstrated the highest efficiency for detecting a probable DSM\u20105 PTSD diagnosis on the PCL\u20105 (\u03ba[Eff]\u00a0=\u00a0.60). Item response theory analyses indicated that item 2 (avoidance) of the PC\u2010PTSD\u20105 yielded the most informative data, with other items potentially lacking incremental utility.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Although not an instrument validation study, these findings offer efficient evidence for using the PC\u2010PTSD\u20105 as a succinct screening tool among cancer survivors in a clinical context.<\/jats:p><\/jats:sec><jats:sec><jats:title>Trials Registration<\/jats:title><jats:p><jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/ClinicalTrials.gov\">ClinicalTrials.gov<\/jats:ext-link>, NCT04058795, registered 8\/16\/2019<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.35504","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T13:29:45Z","timestamp":1723642185000},"page":"4118-4126","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Assessing the utility of the PC\u2010PTSD\u20105 as a screening tool among a cancer survivor sample"],"prefix":"10.1002","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7809-0339","authenticated-orcid":false,"given":"Sophia K.","family":"Smith","sequence":"first","affiliation":[{"name":"School of Nursing Duke University  Durham North Carolina USA"},{"name":"Duke Cancer Institute Duke University Medical Center  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cole","family":"Manschot","sequence":"additional","affiliation":[{"name":"North Carolina State University  Raleigh North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Kuhn","sequence":"additional","affiliation":[{"name":"Dissemination and Training Division National Center for PTSD  Palo Alto California USA"},{"name":"Department of Psychiatry and Behavioral Sciences School of Medicine Stanford University  Stanford California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Laber","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Bioinformatics Duke University  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8809-2979","authenticated-orcid":false,"given":"Tamara J.","family":"Somers","sequence":"additional","affiliation":[{"name":"Duke Cancer Institute Duke University Medical Center  Durham North Carolina USA"},{"name":"Department of Psychiatry and Behavioral Sciences Duke University Medical Center  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen L.","family":"Syrjala","sequence":"additional","affiliation":[{"name":"Clinical Research Division Fred Hutchinson Cancer Center  Seattle Washington USA"},{"name":"Department of Psychiatry and Behavioral Sciences University of Washington School of Medicine  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allison J.","family":"Applebaum","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Memorial Sloan Kettering Cancer Center  New York New York USA"},{"name":"Department of Psychology in Psychiatry Weill Cornell Medicine  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215\u20100366(17)30014\u20107"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.12.3414"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtct.2021.01.011"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2018.08.002"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.73.2800"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2020.38.15_suppl.7505"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3654"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.3851"},{"key":"e_1_2_10_10_1","unstructured":"BolonYT AtshanR Allbee\u2010JohnsonM Estrada\u2010MerlyN LeeSJ.Summary slides & reports. 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