{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:31:32Z","timestamp":1791617492427,"version":"4.3.4"},"reference-count":149,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Despite significant advances in breast cancer control and survival with endocrine therapies (ETs), treatment utilization and outcomes in developing countries have not been adequately explored. This review evaluated ET adherence, potential benefits, and harms in populations across developing countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A literature search was conducted through August 2023 in five databases: PubMed, Cochrane Library, Web of Science, Global Health, and WHO Global Index Medicus. Retrieved records were screened to identify observational research presenting at least one outcome in women with nonmetastatic breast cancer in developing countries who received ET (tamoxifen or aromatase inhibitors). A random effects model was used to compute the rates of adherence, discontinuation, adverse events (AEs), disease progression, and death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 104 studies met the inclusion criteria. Risk of bias was low in most studies, and a large portion of the patients involved Asians. The overall heterogeneity between studies was partially attributed to variations in study design or outcome measurement method. Results showed a pooled adherence rate of 75% (95% confidence interval [CI], 67%\u201381%) and a discontinuation rate of 16% (95% CI, 10%\u201325%). Treatment side effects and young age consistently emerged as significant predictors of nonadherence. A wide range of AEs was identified in our analysis. The estimated average rates of cancer recurrence and mortality at 5\u2010years were 16% and 8%, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The findings of this study underscore suboptimal ET use in developing countries and provide comprehensive insights into treatment experiences in the real\u2010world setting. Targeted strategies are warranted to enhance adherence and subsequently optimize treatment benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.35550","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T07:45:42Z","timestamp":1725522342000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Adherence, clinical benefits, and adverse effects of endocrine therapies among women with nonmetastatic breast cancer in developing countries: A systematic review and meta\u2010analysis"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7279-4418","authenticated-orcid":false,"given":"Shaimaa","family":"Elshafie","sequence":"first","affiliation":[{"name":"Department of Clinical and Administrative Pharmacy College of Pharmacy University of Georgia  Athens Georgia USA"},{"name":"Central Administration for Drug Control Egyptian Drug Authority  Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupal","family":"Trivedi","sequence":"additional","affiliation":[{"name":"Department of Clinical and Administrative Pharmacy College of Pharmacy University of Georgia  Athens Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo A.","family":"Villa\u2010Zapata","sequence":"additional","affiliation":[{"name":"Department of Clinical and Administrative Pharmacy College of Pharmacy University of Georgia  Athens Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Randall L.","family":"Tackett","sequence":"additional","affiliation":[{"name":"Department of Clinical and Administrative Pharmacy College of Pharmacy University of Georgia  Athens Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iman Y.","family":"Zaghloul","sequence":"additional","affiliation":[{"name":"School of Pharmacy Massachusetts College of Pharmacy and Health Sciences  Boston Massachusetts USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henry N.","family":"Young","sequence":"additional","affiliation":[{"name":"Department of Clinical and Administrative Pharmacy College of Pharmacy University of Georgia  Athens Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,9,5]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen\u20102017\u2010016982"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.02529"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.32406"},{"key":"e_1_2_8_6_1","article-title":"Surveillance, epidemiology, and end results program","author":"National Cancer Institute","year":"2022","journal-title":"Breast: SEER 5\u2010Year Relative Survival Rates"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2022.102339"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(21)00462\u20109"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214\u2010109X(20)30261\u20108"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13964"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy136"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572\u2010019\u20100111\u20102"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214\u2010109X(22)00376\u2010X"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1200\/GO.21.00282"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1701830"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2022.01.012"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1200\/OP.20.00248"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.25.9655"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010010\u20101132\u20104"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2022.04.007"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol29060349"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2019.04.1927"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096\u2010017\u20100570\u2010z"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n71"},{"key":"e_1_2_8_25_1","unstructured":"United Nations.World Economic Situation and Prospects (WESP) 2023 report. Accessed June 1 2023.https:\/\/www.un.org\/development\/desa\/dpad\/publication\/world\u2010economic\u2010situation\u2010and\u2010prospects\u20102023\/"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40779\u2010020\u201000238\u20108"},{"key":"e_1_2_8_27_1","unstructured":"Joanna Briggs Institute.The JBI critical appraisal tools. Accessed February 5 2024.https:\/\/jbi.global\/critical\u2010appraisal\u2010tools"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12874\u2010021\u201001381\u2010z"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/jrsm.1547"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/cts.12707"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.5114\/wo.2017.72397"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102407\u201014\u2010397"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1590\/s0034\u20108910.2014048004799"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.862224"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.3017"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S167004"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.18454"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102407\u201012\u2010161"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.27212"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnci.2012.06.003"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1159\/000500318"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1159\/000353978"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S296747"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2021.05.013"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.24780"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2022.01.017"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.5306\/wjco.v13.i8.712"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.4103\/2347\u20105625.212864"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010022\u201006835\u20106"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20107819\u20105\u2010108"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000013976"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.4103\/apjon.apjon_45_17"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(22)00198\u2010X"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2020.153365"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.4103\/tcmj.tcmj_17_19"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12957"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kjms.2015.04.002"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0087027"},{"issue":"2","key":"e_1_2_8_59_1","article-title":"An electronic non\u2010interventional pharmacovigilance study of early\u2010stage breast cancer patients on adjuvant treatment with anastrozole (Arimidex)","volume":"26","author":"Uskent N","year":"2011","journal-title":"Turk J Oncol"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.14740\/wjon1647"},{"issue":"6","key":"e_1_2_8_61_1","first-page":"357","article-title":"[Adherence to adjuvant hormonal therapy in patients with breast cancer]","volume":"57","author":"Camejo\u2010Mart\u00ednez N","year":"2019","journal-title":"Rev Med Inst Mex Seguro Soc"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.661443"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.83045"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.815960"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.759595"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1177\/0300060518807100"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2016.12.004"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000001718"},{"issue":"8","key":"e_1_2_8_69_1","first-page":"3585","article-title":"Association of CYP2D6*10 (c.100C>T) polymorphisms with clinical outcome of breast cancer after tamoxifen adjuvant endocrine therapy in Chinese population","volume":"8","author":"Lei L","year":"2016","journal-title":"Am J Transl Res"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010010\u20101096\u20104"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112152\u2010112152\u201020191112\u201000728"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12032\u2010014\u20100128\u2010z"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010020\u201005656\u20109"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.4048\/jbc.2021.24.e41"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajg.2011.01.003"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00268\u2010014\u20102542\u2010y"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1200\/GO.21.00246"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics13040792"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010022\u201006765\u20103"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.980197"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.636378"},{"key":"e_1_2_8_82_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.844926"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2008.19.4.256"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00366"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010011\u20101728\u20103"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2017.05.002"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2016.04.017"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0159098"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.4048\/jbc.2007.10.2.134"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.4048\/jbc.2019.22.e53"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010010\u20101172\u20103"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14030508"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010020\u201057726\u2010z"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010014\u20103140\u20102"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.cad.0000215056.47695.92"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010017\u20103559\u2010z"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010022\u201007345\u20103"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0068798"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0140842"},{"key":"e_1_2_8_100_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102407\u201010\u2010453"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.1080\/13697137.2018.1540563"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.21037\/tcr.2018.12.27"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2023.1170077"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.4069\/kjwhn.2021.01.19"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.20.5435"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885\u2010022\u201010148\u20108"},{"key":"e_1_2_8_107_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43042\u2010022\u201000332\u20107"},{"issue":"6","key":"e_1_2_8_108_1","first-page":"358","article-title":"Health care factors associated with survival among women with breast cancer on hormone therapy in Rio de Janeiro, Brazil, 2004 \u2010 2010","volume":"39","author":"Brito C","year":"2016","journal-title":"Rev Panam Salud Publica"},{"key":"e_1_2_8_109_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.091298"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445\u20102197.1997.tb01910.x"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnci.2013.02.001"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctarc.2021.100350"},{"issue":"3","key":"e_1_2_8_113_1","first-page":"185","article-title":"A prospective study of estrogen, progesterone & HER2NEU receptor in cases of breast cancer in a tertiary care hospital of Bhavnagar, Gujarat, Western India","volume":"5","author":"Hathila TN","year":"2015","journal-title":"Natl J Med Res"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1460396909990239"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.4103\/0019\u2010509x.15099"},{"issue":"2","key":"e_1_2_8_116_1","first-page":"321","article-title":"Hormone receptor status of operable breast cancers in Indonesia: correlation with other prognostic factors and survival","volume":"7","author":"Aryandono T","year":"2006","journal-title":"Asian Pac J Cancer Prev"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1385\/MO:22:4:343"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02785842"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph14090925"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2021.101.6.315"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010018\u20104681\u20106"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010017\u20104111\u20101"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.4048\/jbc.2020.23.e58"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.4048\/jbc.2014.17.4.350"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2011.26.8.1007"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010011\u20101425\u20102"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2009.01.016"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.1186\/bcr3221"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0262934"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2015.03.003"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.2147\/BCTT.S67553"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1151733"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.4999\/uhod.14453"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1200\/GO.21.00289"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/217047"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.15386\/mpr\u20101201"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djy136"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33596"},{"key":"e_1_2_8_139_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2022.861198"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41523\u2010022\u201000414\u20100"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764\u2010020\u201000908\u20105"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010018\u201005073\u2010z"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.25485"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055\u20109965.EPI\u201020\u20100604"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1177\/1078155219835297"},{"key":"e_1_2_8_146_1","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocy118"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vhri.2021.05.005"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13841"},{"key":"e_1_2_8_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2021.102264"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.63.8619"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.35550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T10:58:23Z","timestamp":1760266703000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.35550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,5]]},"references-count":149,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1002\/cncr.35550"],"URL":"https:\/\/doi.org\/10.1002\/cncr.35550","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,5]]},"assertion":[{"value":"2024-06-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e35550"}}