{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T02:08:10Z","timestamp":1789006090257,"version":"build-2803163510"},"reference-count":51,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T00:00:00Z","timestamp":1744675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2025,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Mortgage lending bias is a critical driver of residential segregation, and may contribute to disparities in cancer survival. This study investigated the association between contemporary redlining and racial lending bias and prostate cancer survival.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cohort study used a Surveillance, Epidemiology, and End Results\u2013Medicare database that included 34,163 Black and White men diagnosed with prostate cancer between 2010 and 2013. Home Mortgage Disclosure Act data were used to calculate the census\u2010tract redlining index (the systematic denial of mortgages based on property location) and racial lending bias index (the systematic denial of a mortgage application for a Black applicant compared with a White applicant in the local area). Both indices were assessed continuously and categorically (low, moderate, or high). Multivariable\u2010adjusted Cox models were used to estimate hazard ratios (HRs) for prostate cancer\u2013specific and all\u2010cause mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Overall, as the redlining index increased, men experienced poorer prostate cancer survival. Compared to men residing in low\u2010redlined neighborhoods, those in high\u2010redlined neighborhoods had an increased risk of prostate cancer\u2013specific mortality (HR,\u00a01.21; 95% confidence interval [CI], 1.03\u20131.42) and all\u2010cause mortality (HR,\u00a01.25; 95% CI, 1.17\u20131.34). Similar results were observed for redlining in a race\u2010stratified analysis among Black and White men. Among White men, compared with those residing in low racial lending bias neighborhoods, those in high racial lending bias neighborhoods had an increased all\u2010cause mortality risk (HR,\u00a01.11; 95% CI, 1.03\u20131.21).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Contemporary redlining was associated with poorer prostate cancer survival in the overall population. However, an association between racial lending bias and elevated mortality was only observed among White men. Findings suggest that mortgage lending discrimination may contribute to disparities in prostate cancer survival.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.35850","type":"journal-article","created":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T13:49:56Z","timestamp":1744724996000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Contemporary neighborhood redlining and racial mortgage lending bias and disparities in prostate cancer survival"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2992-5897","authenticated-orcid":false,"given":"Wayne R.","family":"Lawrence","sequence":"first","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal D.","family":"Freedman","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health  Rockville Maryland USA"},{"name":"Division of Cancer Control and Population Sciences National Cancer Institute National Institutes of Health  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer K.","family":"McGee\u2010Avila","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health  Rockville Maryland USA"},{"name":"Division of Cancer Control and Population Sciences National Cancer Institute National Institutes of Health  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyokyoung G.","family":"Hong","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5143-4867","authenticated-orcid":false,"given":"Scarlett L.","family":"Gomez","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics University of California San Francisco  San Francisco California USA"},{"name":"Helen Diller Family Comprehensive Cancer Center University of California San Francisco  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7747-224X","authenticated-orcid":false,"given":"Andrew P.","family":"Loehrer","sequence":"additional","affiliation":[{"name":"Geisel School of Medicine at Dartmouth  Hanover New Hampshire USA"},{"name":"Dartmouth Cancer Center  Lebanon New Hampshire USA"},{"name":"Department of Surgery Dartmouth Hitchcock Medical Center  Lebanon New Hampshire USA"},{"name":"The Dartmouth Institute for Health Policy and Clinical Practice  Lebanon New Hampshire USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7513-8528","authenticated-orcid":false,"given":"Kirsten M. 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