{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T06:42:14Z","timestamp":1785825734546,"version":"3.56.0"},"reference-count":156,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Appendiceal tumors comprise a heterogeneous group of tumors that frequently disseminate to the peritoneum. Management of appendiceal tumors is lacking high\u2010quality data given their rarity and heterogeneity. In general, appendiceal tumor treatment is extrapolated in part from colorectal cancer or pooled studies, without definitive evidence of disease\u2010specific benefit. Many practices are controversial and vary widely between institutions. A national consensus update of best management practices for appendiceal malignancies was performed to better standardize care. Herein, the authors present recommendations for the management of appendiceal tumors with peritoneal involvement.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>As previously described, modified Delphi consensus was performed to update the previous 2018 Chicago Consensus guideline. Recommendations were supported by using rapid systematic reviews of key issues in surgical and systemic therapy. Key pathology concepts and recommendations were synthesized in collaboration with content experts.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A consensus\u2010based pathway was generated for any type of non\u2010neuroendocrine appendiceal tumor with peritoneal involvement. The first round of Delphi consensus included 138 participants, of whom 133 (96%) participated in the second round, and greater than 90% consensus was achieved for all pathway blocks. Key items included recommending evaluation for cytoreduction to most patients with low\u2010grade peritoneal disease who are surgical candidates and to many patients with high\u2010grade disease, as well as timing of systemic chemotherapy and surveillance protocols. Common pitfalls in pathologic classification and their clinical implications are also presented.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These consensus recommendations provide guidance regarding the management of appendiceal tumors with peritoneal involvement, including a review of current evidence in the management of recurrent and unresectable disease.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.35874","type":"journal-article","created":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T09:00:56Z","timestamp":1750842056000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Consensus guideline for the management of patients with appendiceal tumors, part 2: Appendiceal tumors with peritoneal involvement"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9258-4706","authenticated-orcid":false,"given":"Elizabeth L.","family":"Godfrey","sequence":"first","affiliation":[{"name":"Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Forest","family":"Mahoney","sequence":"additional","affiliation":[{"name":"Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9973-0884","authenticated-orcid":false,"given":"Varun V.","family":"Bansal","sequence":"additional","affiliation":[{"name":"Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David G.","family":"Su","sequence":"additional","affiliation":[{"name":"Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David N.","family":"Hanna","sequence":"additional","affiliation":[{"name":"Section of Surgical Sciences Division of Surgical Oncology and Endocrine Surgery Department of Surgery Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Lopez\u2010Ramirez","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology Mercy Medical Center The Institute for Cancer Care  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekaterina","family":"Baron","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Marshfield Medical Center  Marshfield Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8541-586X","authenticated-orcid":false,"given":"Kiran K.","family":"Turaga","sequence":"additional","affiliation":[{"name":"Department of Surgery Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Al B.","family":"Benson","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology Department of Medicine Northwestern University  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Namrata","family":"Setia","sequence":"additional","affiliation":[{"name":"Department of Pathology University of Chicago Medical Center  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua H.","family":"Winer","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Department of Surgery Emory University School of Medicine  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig G.","family":"Gunderson","sequence":"additional","affiliation":[{"name":"Veterans Affairs Connecticut Healthcare System  West Haven Connecticut USA"},{"name":"Department of Medicine Yale School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rupen","family":"Shah","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Henry Ford Cancer Institute\/Henry Ford Health  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepa R.","family":"Magge","sequence":"additional","affiliation":[{"name":"Section of Surgical Sciences Division of Surgical Oncology and Endocrine Surgery Department of Surgery Vanderbilt University Medical Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Solsky","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Department of Surgery College of Medicine University of Tennessee Health Science Center  Memphis Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2335-0612","authenticated-orcid":false,"given":"Cathy","family":"Eng","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology Department of Medicine Vanderbilt\u2010Ingram Cancer Center  Nashville Tennessee USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oliver S.","family":"Eng","sequence":"additional","affiliation":[{"name":"Division of Surgical Oncology Department of Surgery University of California Irvine  Orange California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ardaman","family":"Shergill","sequence":"additional","affiliation":[{"name":"Section of Hematology\/Oncology Department of Medicine University of Chicago Medical Center  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John Paul","family":"Shen","sequence":"additional","affiliation":[{"name":"Department of Gastrointestinal Medical Oncology The University of Texas MD Anderson Cancer Center  Houston Texas USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Misdraji","sequence":"additional","affiliation":[{"name":"Department of Pathology Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Foote","sequence":"additional","affiliation":[{"name":"Department of Medicine Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyi","family":"Luo","sequence":"additional","affiliation":[{"name":"Department of Pathology Yale University School of Medicine  New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Peritoneal Surface Malignancies Consortium Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2020.02.012"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001530"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.16161"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/EDBK_321009"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010020\u201008316\u2010w"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.35867"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010014\u20102726\u20107"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010012\u20102238\u20101"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0000000000000210"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2020.08.017"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1515\/pp\u20102023\u20100001"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010022\u201012753\u20100"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2020.6363"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000001076"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010015\u20104995\u20100"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416\u2010020\u20101015\u20103"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010017\u20105938\u20108"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.29744"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2016.03.017"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0000000000000719"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010017\u20106252\u20101"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.4251\/wjgo.v2.i1.44"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2014.37"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4393"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010199402000\u201000002"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478\u2010199512000\u201000006"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010012\u20102241\u20106"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.39.7166"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010014\u20104147\u2010y"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15041326"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14189"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15778"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957\u2010016\u20100996\u20100"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010016\u20105588\u20102"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010020\u201008535\u20101"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181af6067"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010017\u20106305\u20105"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31817ec31e"},{"key":"e_1_2_12_40_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010020\u201009499\u2010y"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2018.06.023"},{"key":"e_1_2_12_42_1","doi-asserted-by":"publisher","unstructured":"PSM Writing Group PSM Consortium Group TuragaKK.Consensus guidelines for the management of peritoneal surface malignancies: introduction and methodology [preprint].medRxiv. Published online April 9 2024. doi:10.1101\/2024.04.07.24305467","DOI":"10.1101\/2024.04.07.24305467"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010022\u201011894\u20106"},{"key":"e_1_2_12_44_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010014\u20104335\u20109"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6604522"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24715"},{"issue":"2","key":"e_1_2_12_47_1","first-page":"135","article-title":"Surgical cytoreduction and intraperitoneal chemotherapy for peritoneal carcinomatosis arising from the appendix","volume":"52","author":"Sideris L","year":"2009","journal-title":"Can J Surg"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0000000000000878"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010020\u201009064\u20107"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010015\u20105019\u20109"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.26759"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350\u2010006\u20100741\u20109"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010006\u20109174\u2010x"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.27087"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957\u2010021\u201002171\u2010z"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1097\/DCR.0b013e3182a62b0d"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010015\u20104838\u2010z"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1158\/2767\u20109764.CRC\u201024\u20100019"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010021\u201010093\u2010z"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2016.08.021"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs5.50262"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010021\u201011233\u20101"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010022\u201011440\u20104"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00595\u2010019\u201001856\u2010z"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010020\u201008482\u2010x"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010007\u20109462\u20100"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010019\u201004239\u20104"},{"key":"e_1_2_12_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.esmoop.2023.101030"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010021\u201010994\u2010z"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.esmoop.2023.101619"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658\u2010196102000\u201000015"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021\u20109681(61)90095\u20109"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.4854.135"},{"issue":"4","key":"e_1_2_12_74_1","first-page":"397","article-title":"Mucocele of the appendix with globoid body formation","volume":"1","author":"Milliken G","year":"1925","journal-title":"Am J Pathol"},{"key":"e_1_2_12_75_1","first-page":"500","article-title":"Mucocele of the appendix: with report of two cases","volume":"28","author":"Weaver DD","year":"1928","journal-title":"Calif West Med"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2015.04.052"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.26.6.413"},{"key":"e_1_2_12_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(197312)32:6<1525::AID\u2010CNCR2820320632>3.0.CO;2\u2010C"},{"key":"e_1_2_12_79_1","first-page":"197","article-title":"Pseudomyxoma\u00a0peritonei: new concepts in diagnosis, origin, nomenclature, and relationship to mucinous borderline (low malignant potential) tumors of the ovary","volume":"2","author":"Ronnett BM","year":"1997","journal-title":"Anat Pathol"},{"key":"e_1_2_12_80_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(197605)37:5<2493::aid\u2010cncr2820370543>3.0.co;2\u2010d"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(19950201)75:3<757::AID\u2010CNCR2820750303>3.0.CO;2\u2010F"},{"issue":"4","key":"e_1_2_12_82_1","first-page":"314","article-title":"Unusual tumors of the appendix and pseudomyxoma peritonei","volume":"13","author":"Carr NJ","year":"1996","journal-title":"Semin Diagn Pathol"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478\u2010200308000\u201000006"},{"key":"e_1_2_12_84_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000535"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000202039.74837.7d"},{"key":"e_1_2_12_86_1","first-page":"211","volume-title":"WHO Classification of Female Genital Tumors","author":"Misdraji J","year":"2020"},{"key":"e_1_2_12_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(197408)34:2<338::AID\u2010CNCR2820340218>3.0.CO;2\u2010W"},{"key":"e_1_2_12_88_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/94.1.27"},{"key":"e_1_2_12_89_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097\u20100142(197812)42:6<2781::aid\u2010cncr2820420638>3.0.co;2\u2010b"},{"key":"e_1_2_12_90_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31817f1816"},{"key":"e_1_2_12_91_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001056"},{"key":"e_1_2_12_92_1","first-page":"135","volume-title":"WHO Classification of Tumours: Digestive System Tumours","author":"Misdraji J","year":"2019"},{"key":"e_1_2_12_93_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-40618-3"},{"key":"e_1_2_12_94_1","volume-title":"AJCC Cancer Staging System","author":"Goodman KA","year":"2023"},{"key":"e_1_2_12_95_1","volume-title":"WHO Classification of Tumours of the Digestive System","author":"Bosman FT","year":"2010"},{"key":"e_1_2_12_96_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-88441-7"},{"key":"e_1_2_12_97_1","doi-asserted-by":"publisher","DOI":"10.4021\/gr2009.01.1267"},{"key":"e_1_2_12_98_1","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2019\u20100214\u2010OA"},{"key":"e_1_2_12_99_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010019\u201007447\u2010z"},{"key":"e_1_2_12_100_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0179216"},{"key":"e_1_2_12_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41379\u2010019\u20100435\u20101"},{"key":"e_1_2_12_102_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2022.07.004"},{"key":"e_1_2_12_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2022.01.008"},{"key":"e_1_2_12_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880572"},{"key":"e_1_2_12_105_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e318282649b"},{"key":"e_1_2_12_106_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100035\u20101564433"},{"key":"e_1_2_12_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10350\u2010005\u20100196\u20104"},{"key":"e_1_2_12_108_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.14.5763"},{"key":"e_1_2_12_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2014.03.007"},{"key":"e_1_2_12_110_1","volume-title":"Protocol for the Examination of Specimens from Patients With Carcinoma of the Appendix","author":"College of American Pathologists","year":"2022"},{"key":"e_1_2_12_111_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010017\u20106310\u20108"},{"key":"e_1_2_12_112_1","doi-asserted-by":"publisher","DOI":"10.1515\/pp\u20102016\u20100011"},{"key":"e_1_2_12_113_1","doi-asserted-by":"publisher","DOI":"10.1111\/his.14092"},{"key":"e_1_2_12_114_1","doi-asserted-by":"publisher","DOI":"10.1200\/PO.17.00302"},{"key":"e_1_2_12_115_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010019\u201007879\u20107"},{"key":"e_1_2_12_116_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010020\u201008210\u20105"},{"key":"e_1_2_12_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2015.12.012"},{"key":"e_1_2_12_118_1","doi-asserted-by":"publisher","DOI":"10.1158\/1541\u20107786.MCR\u201022\u20100801"},{"key":"e_1_2_12_119_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22"},{"key":"e_1_2_12_120_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010021\u201010945\u20108"},{"key":"e_1_2_12_121_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2014\u20100294"},{"key":"e_1_2_12_122_1","doi-asserted-by":"publisher","DOI":"10.1177\/17588359221112478"},{"key":"e_1_2_12_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2006.12.048"},{"key":"e_1_2_12_124_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010008\u20100073\u20101"},{"key":"e_1_2_12_125_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20107819\u201012\u2010332"},{"key":"e_1_2_12_126_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010007\u20109691\u20102"},{"key":"e_1_2_12_127_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010011\u20101714\u20103"},{"key":"e_1_2_12_128_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21679"},{"key":"e_1_2_12_129_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/163284"},{"key":"e_1_2_12_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2022.07.018"},{"key":"e_1_2_12_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2021.01.010"},{"key":"e_1_2_12_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2015.01.005"},{"key":"e_1_2_12_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.25967"},{"issue":"3","key":"e_1_2_12_134_1","first-page":"783","article-title":"Perioperative systemic chemotherapy for peritoneal mucinous appendiceal carcinomas treated with cytoreductive surgery & HIPEC","volume":"22","author":"Spiliotis J","year":"2017","journal-title":"J BUON"},{"key":"e_1_2_12_135_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876\u2010023\u201003019\u20104"},{"key":"e_1_2_12_136_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010021\u201011213\u20105"},{"key":"e_1_2_12_137_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2017\u20100081"},{"key":"e_1_2_12_138_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010022\u201005489\u20105"},{"key":"e_1_2_12_139_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010014\u20103985\u2010y"},{"key":"e_1_2_12_140_1","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2078\u20106891.2015.101"},{"key":"e_1_2_12_141_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdr279"},{"key":"e_1_2_12_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2022.04.007"},{"key":"e_1_2_12_143_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010007\u20109393\u20109"},{"key":"e_1_2_12_144_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02574513"},{"key":"e_1_2_12_145_1","doi-asserted-by":"publisher","DOI":"10.1002\/jso.20107"},{"key":"e_1_2_12_146_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182602ad2"},{"key":"e_1_2_12_147_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2024.0260"},{"key":"e_1_2_12_148_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010019\u201008117\u2010w"},{"key":"e_1_2_12_149_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11605\u2010008\u20100774\u20106"},{"key":"e_1_2_12_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2007.04.002"},{"key":"e_1_2_12_151_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555\u2010023\u201010088\u20100"},{"key":"e_1_2_12_152_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010020\u201008841\u20108"},{"key":"e_1_2_12_153_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2023.41.4_suppl.226"},{"key":"e_1_2_12_154_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010012\u20102783\u20107"},{"key":"e_1_2_12_155_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010012\u20102789\u20101"},{"key":"e_1_2_12_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.04.019"},{"key":"e_1_2_12_157_1","doi-asserted-by":"publisher","DOI":"10.1245\/s10434\u2010019\u201007526\u20101"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.35874","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T20:29:48Z","timestamp":1760300988000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.35874"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,25]]},"references-count":156,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1002\/cncr.35874"],"URL":"https:\/\/doi.org\/10.1002\/cncr.35874","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,25]]},"assertion":[{"value":"2024-07-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e35874"}}