{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:53:43Z","timestamp":1788998023308,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T00:00:00Z","timestamp":1745971200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>People with HIV (PWH) are less likely to receive cancer treatment compared to those without HIV. The objective of this study was to evaluate the role of area\u2010level social determinants of health (SDoH) in cancer treatment receipt among PWH and cancer in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The authors used the National Cancer Database (NCDB; 2004\u20132020) and included adult patients (18\u201389 years) with HIV, identified via\n                      <jats:italic>International Classification of Diseases<\/jats:italic>\n                      (\n                      <jats:italic>ICD<\/jats:italic>\n                      )\u2010\n                      <jats:italic>9<\/jats:italic>\n                      and\n                      <jats:italic>ICD<\/jats:italic>\n                      \u2010\n                      <jats:italic>10<\/jats:italic>\n                      codes. We focused on the 14 most common cancers common among PWH. The primary outcome was receipt of first\u2010line curative cancer treatment as documented by NCDB. Key SDoH exposures were area\u2010level educational attainment (percent of adults without a high school degree) and income (median income quartiles) by zip code. Hierarchical multivariable logistic regression models, clustered by cancer treatment facility, were used to estimate adjusted odds ratios (aORs) with 95% confidence intervals (CIs).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The authors included 31,549 people with HIV and cancer, 16.5% of whom did not receive first\u2010line curative cancer treatment. Overall, 43% were \u226560 years old, 38% were non\u2010Hispanic Black, 68% were male, and 39% resided in the Southern United States. The most common cancers were lung (21%), diffuse large B\u2010cell lymphoma or DLBCL (12%), colorectal (9%), and prostate (9%). PWH living in areas of lowest educational attainment (quartile [Q]4 vs. Q1: aOR, 0.73; 95% CI, 0.66\u20130.82) and lowest\u2010income (Q4 vs. Q1: aOR, 0.73; 95% CI, 0.65\u20130.81) areas were less likely to receive cancer treatment, after adjusting for age, sex, stage, year, and cancer type.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Area\u2010level SDoH are associated with cancer treatment receipt among PWH, suggesting structural factors may impact this long\u2010standing observed inequity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.35881","type":"journal-article","created":{"date-parts":[[2025,4,30]],"date-time":"2025-04-30T22:22:59Z","timestamp":1746051779000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Investigating structural inequities in area\u2010level socioeconomic and health care access measures among people with HIV and cancer (2004\u20132020)"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3690-3848","authenticated-orcid":false,"given":"Jessica Y.","family":"Islam","sequence":"first","affiliation":[{"name":"Center for Immunization and Infection Research in Cancer H. Lee Moffitt Cancer Center Research Institute  Tampa Florida USA"},{"name":"Department of Cancer Epidemiology H. Lee Moffitt Cancer Center and Research Institute  Tampa Florida USA"},{"name":"Department of Oncologic Sciences University of South Florida  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gita","family":"Suneja","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Huntsman Cancer Institute University of Utah  Salt Lake City Utah USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6808-6615","authenticated-orcid":false,"given":"Yu Chen","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Health Outcomes and Behavior H. Lee Moffitt Cancer Center and Research Institute  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer K.","family":"McGee\u2010Avila","sequence":"additional","affiliation":[{"name":"Division of Cancer Epidemiology and Genetics Infections and Immunoepidemiology Branch National Cancer Institute  Rockville Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kea","family":"Turner","sequence":"additional","affiliation":[{"name":"Department of Oncologic Sciences University of South Florida  Tampa Florida USA"},{"name":"Department of Health Outcomes and Behavior H. Lee Moffitt Cancer Center and Research Institute  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Alishahi Tabriz","sequence":"additional","affiliation":[{"name":"Department of Oncologic Sciences University of South Florida  Tampa Florida USA"},{"name":"Department of Health Outcomes and Behavior H. Lee Moffitt Cancer Center and Research Institute  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan T.","family":"Vadaparampil","sequence":"additional","affiliation":[{"name":"Department of Oncologic Sciences University of South Florida  Tampa Florida USA"},{"name":"Department of Health Outcomes and Behavior H. Lee Moffitt Cancer Center and Research Institute  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gypsyamber","family":"D\u2019Souza","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Bloomberg School of Public Health Johns Hopkins University  Baltimore Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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