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Such disparities are characterized by racial, socioeconomic, and geographic factors. However, less is known among disaggregated Hispanic populations. This study examines disparities in the receipt of palliative\u2010intent interventions among Hispanic subgroups with advanced lung, breast, and prostate cancer.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Via the National Cancer Data Base, data were collected on the receipt of palliative\u2010intent interventions among Hispanic subgroups diagnosed with American Joint Committee on Cancer analytic stage IV breast, lung, and prostate cancer between 2004 and 2021. Multivariate logistic regressions were conducted to quantify differences in the uptake of palliative\u2010intent\u00a0care among Hispanic subgroups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 945,894 total patients, disaggregated analyses revealed reduced receipt of palliative\u2010intent interventions for patients with lung, breast, and prostate cancer of Mexican descent (lung, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001; breast, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001; prostate, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.03) compared to non\u2010Hispanic White patients. Receipt for patients of South or Central American descent was reduced in comparison to non\u2010Hispanic White patients for lung and breast cancer (lung, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001; breast, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001). Uptake of palliative interventions for metastatic lung and breast cancer was reduced for patients of Cuban descent (lung, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001; breast, <jats:italic>p<\/jats:italic>\u00a0=\u00a0.03), and was lower for patients of Dominican descent with breast cancer, compared to non\u2010Hispanic White patients (<jats:italic>p<\/jats:italic>\u00a0=\u00a0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>These findings demonstrate disparities in the receipt of palliative\u2010intent interventions among disaggregated Hispanic subgroups. This study highlights the need for disaggregated research to further characterize these disparities and their drivers. Community\u2010level and patient\u2010centric efforts may help to address these inequities.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncr.35903","type":"journal-article","created":{"date-parts":[[2025,5,19]],"date-time":"2025-05-19T08:12:39Z","timestamp":1747642359000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Disparities in receipt of palliative\u2010intent treatment among disaggregated Hispanic populations with breast, lung, and prostate cancer in the United States"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5092-3312","authenticated-orcid":false,"given":"Shriya K.","family":"Garg","sequence":"first","affiliation":[{"name":"University of Georgia  Athens Georgia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6411-5729","authenticated-orcid":false,"given":"Khushi","family":"Kohli","sequence":"additional","affiliation":[{"name":"Harvard University  Cambridge Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isha K.","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yash K.","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lilac G.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabella S.","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin Jay G.","family":"Feliciano","sequence":"additional","affiliation":[{"name":"Department of Medicine NYC Health + Hospitals\/Elmhurst Icahn School of Medicine at Mount Sinai  Queens New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yefri A.","family":"Baez","sequence":"additional","affiliation":[{"name":"Department of Urology Brigham and Women's Hospital  Boston Massachusetts USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5406-3232","authenticated-orcid":false,"given":"Brandon A.","family":"Mahal","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology University of Miami Miller School of Medicine and Sylvester Comprehensive Cancer Center  Miami Florida USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Puneeth","family":"Iyengar","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel R.","family":"Gomez","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaitlyn","family":"Lapen","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6119-0889","authenticated-orcid":false,"given":"Edward Christopher","family":"Dee","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology Memorial Sloan Kettering Cancer Center  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,5,19]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1000678"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.10398"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010024\u201008633\u2010w"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noac075"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2024.3102"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1177\/1049909120922779"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2020.11.031"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.14639"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","unstructured":"EmersonMA SpeesLP JacksonBE et\u00a0al.End\u2010of\u2010life care quality for American Indians with cancer.J Natl Cancer Inst. 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