{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T13:11:03Z","timestamp":1789996263280,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T00:00:00Z","timestamp":1756080000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T00:00:00Z","timestamp":1756080000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","award":["PLC\u20101609\u201036291"],"award-info":[{"award-number":["PLC\u20101609\u201036291"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Goal\u2010concordant care is achieved when treatment is aligned with goals. This study describes patient\u2010reported concordance between care goals and treatment intent in advanced cancer compared to other serious illnesses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A post hoc cross\u2010sectional analysis of baseline survey responses was conducted in adult patients enrolled in a multisite trial of advance care planning. Patients reported whether they prefer and whether they are receiving treatment that prioritizes longevity (life\u2010extending care) versus comfort (comfort\u2010focused care). Concordance between care preferences and perceived treatment intent in patients with advanced cancer versus other advanced illnesses was compared. Mortality rates for patients with cancer stratified by perceived care concordance are reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 1099 patients, those with advanced cancer (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0231) reported similar preference for comfort\u2010focused care (49% vs 48%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.47) and had similar 24\u2010month mortality (16% v 13%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.25) as patients with other serious illnesses (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0868). Among patients preferring comfort\u2010focused care, patients with cancer (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0113) were more likely than patients with other illnesses (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0413) to report receiving (discordant) life\u2010extending care (37% vs. 19%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). Among patients with cancer preferring comfort\u2010focused care, there was no statistically significant difference in 24\u2010month mortality between those who reported receiving (discordant) life\u2010extending versus (concordant) comfort\u2010focused care (24% v 15%,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.31).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Compared to patients with other serious illnesses, a relatively large portion of patients with advanced cancer reported that their treatment discordantly focused on longevity over comfort despite their goal to prioritize comfort over longevity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.35976","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T07:01:11Z","timestamp":1756105271000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Patient\u2010reported discordance between care goals and treatment intent in advanced cancer"],"prefix":"10.1002","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9749-2456","authenticated-orcid":false,"given":"Manan P.","family":"Shah","sequence":"first","affiliation":[{"name":"Division of Hematology\/Oncology University of California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil S.","family":"Wenger","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Health Services Research University of California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Glaspy","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology University of California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6697-907X","authenticated-orcid":false,"given":"Ron D.","family":"Hays","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Health Services Research University of California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca L.","family":"Sudore","sequence":"additional","affiliation":[{"name":"Department of Medicine University of California  San Francisco California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Rahimi","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Family Medicine University of California  Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Gibbs","sequence":"additional","affiliation":[{"name":"Departments of Medicine and Family Medicine University of California  Irvine California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidharth","family":"Anand","sequence":"additional","affiliation":[{"name":"Division of Hematology\/Oncology University of California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi\u2010Hong","family":"Tseng","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Health Services Research University of California  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne M.","family":"Walling","sequence":"additional","affiliation":[{"name":"Division of General Internal Medicine and Health Services Research University of California  Los Angeles California USA"},{"name":"VA Greater Los Angeles Healthcare System  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,8,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/pon.5054"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2016.12.331"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa0907901"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.300.14.1665"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1000678"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.c1345"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.16801"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00520\u2010012\u20101443\u20106"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005200050281"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12904\u2010022\u201001075\u20103"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2013.10797"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.2013.001237"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2010.0434"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2021.0033"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010156\u20103\u2010201202070\u201000008"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.3390\/curroncol13020003"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.6397"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2019.0142"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2015.0039"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40271\u2010013\u20100016\u20101"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s41687\u2010017\u20100003\u20108"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136\u2010009\u20109496\u20109"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532\u20105415.2002.50116.x"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22980"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.24761"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269216307080823"}],"container-title":["Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.35976","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cncr.35976","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncr.35976","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T12:49:24Z","timestamp":1789994964000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncr.35976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,25]]},"references-count":26,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2025,9,1]]}},"alternative-id":["10.1002\/cncr.35976"],"URL":"https:\/\/doi.org\/10.1002\/cncr.35976","archive":["Portico"],"relation":{},"ISSN":["0008-543X","1097-0142"],"issn-type":[{"value":"0008-543X","type":"print"},{"value":"1097-0142","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,25]]},"assertion":[{"value":"2025-04-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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