{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T20:26:05Z","timestamp":1784319965213,"version":"3.55.0"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":2,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,15]],"date-time":"2026-02-15T00:00:00Z","timestamp":1771113600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2026,2,15]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Women diagnosed with triple\u2010negative (ER\u2010, PR\u2010, HER2\u2010) breast cancer (TNBC) have poor survival outcomes compared with other breast cancer subtypes. Yet there is little nonexperimental data on whether guideline\u2010concordant therapy translates to better outcomes over time, or about factors associated with receipt of such guideline care. This study addresses these issues.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Using data from the Centers for Disease Control and Prevention National Program of Cancer Registries (NPCR) augmented via medical records abstraction, the authors constructed a cohort of women diagnosed with invasive, nonmetastatic (stage I\u2013III) TNBC in 2004 (\n                      <jats:italic>N<\/jats:italic>\n                      \u00a0=\u00a0747) and followed through 2015. The date and primary cause of death were derived from the NPCR and the National Death Index. Standard\u2010of\u2010care treatment (as aligned with the study\u2019s timeframe) was defined as being guideline concordant (GC) for surgery, radiation therapy, and chemotherapy based on appropriate initiation, regimen, and completion. Through regression modeling, the authors\u00a0examined predictors of being GC and the association of GC with 10\u2010year survival outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Controlling for patient, tumor, and sociodemographic factors, patients whose management was GC had significantly better all\u2010cause survival (hazard ratio [HR], 0.59; 95% confidence interval [CI], 0.45\u20130.77), breast cancer\u2013specific survival (HR, 0.60; 95% CI, 0.42\u20130.86), and also better non\u2010breast cancer survival (HR, 0.63; 95% CI, 0.40\u20131.00), compared with those whose management was Not GC. Treatment at a Commission on Cancer\u2010accredited facility was a significant predictor of receiving GC care (odds ratio, 1.87; 95% CI, 1.34\u20132.59).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Building on this study\u2019s methodology and its findings about the effectiveness of long\u2010standing approaches to TNBC management, additional population\u2010based studies are urgently needed as new therapeutic approaches are being integrated into guidelines and clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.70267","type":"journal-article","created":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T17:51:53Z","timestamp":1771350713000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Receipt of guideline\u2010concordant local and chemotherapy\u2010based systemic therapy for patients with triple\u2010negative breast cancer: 10\u2010year survival outcomes in a multi\u2010state population\u2010based analysis"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6337-7134","authenticated-orcid":false,"given":"Joseph","family":"Lipscomb","sequence":"first","affiliation":[{"name":"Department of Health Policy and Management Rollins School of Public Health, Emory University  Atlanta Georgia USA"},{"name":"Winship Cancer Institute Emory University  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gretchen G.","family":"Kimmick","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology, Department of Medicine Duke University Medical Center  Durham North Carolina USA"},{"name":"Duke Cancer Institute  Durham North Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Frank","family":"Wilson","sequence":"additional","affiliation":[{"name":"Radiation Oncology Medical College of Wisconsin Cancer Center  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Currey","sequence":"additional","affiliation":[{"name":"Radiation Oncology Program, Department of Radiation Oncology Medical College of Wisconsin  Milwaukee Wisconsin USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5563-9325","authenticated-orcid":false,"given":"Jeffrey M.","family":"Switchenko","sequence":"additional","affiliation":[{"name":"Winship Cancer Institute Emory University  Atlanta Georgia USA"},{"name":"Department of Biostatistics and Bioinformatics Rollins School of Public Health, Emory University  Atlanta Georgia USA"},{"name":"Biostatistics Shared Resource Winship Cancer Institute Emory University  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3663-5027","authenticated-orcid":false,"given":"Xiao\u2010Cheng","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology Louisiana State University Health Sciences Center  New Orleans Louisiana USA"},{"name":"Louisiana Tumor Registry  New Orleans Louisiana USA"},{"name":"Louisiana SEER Program  New Orleans Louisiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemary D.","family":"Cress","sequence":"additional","affiliation":[{"name":"Public Health Institute Cancer Registry of Greater California  Sacramento California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Toumbacaris","sequence":"additional","affiliation":[{"name":"Department of Epidemiology &amp; Biostatistics Memorial Sloan\u2010Kettering Cancer Center  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin C.","family":"Ward","sequence":"additional","affiliation":[{"name":"Winship Cancer Institute Emory University  Atlanta Georgia USA"},{"name":"Department of Epidemiology Rollins School of Public Health Emory University  Atlanta Georgia USA"},{"name":"Georgia Center for Cancer Statistics Rollins School of Public Health, Emory University  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer M.","family":"Wike","sequence":"additional","affiliation":[{"name":"Contractor to the National Program of Cancer Registries Cancer Surveillance Branch, Division of Cancer Prevention and Control Centers for Disease Control and Prevention  Atlanta Georgia USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010016\u20104059\u20106"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32207"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22618"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10549\u2010008\u20109926\u20103"},{"key":"e_1_2_9_6_1","unstructured":"National Cancer Institute.SEER*Explorer: an interactive website for SEER cancer statistics. 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