{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T05:43:04Z","timestamp":1784180584818,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T00:00:00Z","timestamp":1775692800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["24K11513"],"award-info":[{"award-number":["24K11513"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2026,4,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Extranodal marginal zone lymphoma of mucosa\u2010associated lymphoid tissue (MALT lymphoma) with pulmonary involvement is a rare, indolent lymphoma with no standard treatment approaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>To clarify patient characteristics, treatment, and prognosis of pulmonary MALT lymphoma in the modern era, a multi\u2010institutional observational study of patients diagnosed between 2013 and 2022 was conducted. A modified Ann Arbor system was used for the analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 186 eligible patients, 131 (70%) had stage IE\/IIE disease, whereas 55 (30%) had stage IV disease. No patient had stage III disease. With a median follow\u2010up of 57 months, the 4\u2010year overall survival (OS) rates for the stage IE, IIE, and IV groups were 96%, 92%, and 90%, respectively. The stage IIE and IV groups had similar progression\u2010free survival (PFS) that was significantly worse than that of the stage IE group (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). In stage IE\/IIE patients, no differences were found in OS (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.89) or PFS (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.90) among the first\u2010line treatment groups. In stage IV patients, the stomach was the most common synchronous extranodal site of involvement (36%). There were no differences in OS among the first\u2010line treatment groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a0.64).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The OS of patients with MALT lymphoma with pulmonary involvement was favorable regardless of first\u2010line treatment modality, including watchful waiting. The short PFS in the stage IIE and IV groups indicates that these groups are candidates for therapeutic development.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.70390","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T12:35:27Z","timestamp":1775738127000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Treatment and outcomes of pulmonary mucosa\u2010associated lymphoid tissue lymphoma: A multicenter analysis of 186 patients"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0225-5049","authenticated-orcid":false,"given":"Kazutaka","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Hematology and Oncology Mie University Graduate School of Medicine  Tsu 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