{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T15:03:03Z","timestamp":1784300583966,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The lifestyle\u2010based World Cancer Research Fund (WCRF)\/American Institute for Cancer Research (AICR) Cancer Prevention Recommendations aim to reduce cancer risk. People living with and beyond cancer are also encouraged to follow these recommendations, but evidence for their benefit in cancer survivors is limited. The authors investigated associations between adherence to the recommendations and survival among people with cancer within UK Biobank.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The UK Biobank recruited participants between 2006 and 2010. Lifestyle and sociodemographic data were collected at baseline. Adherence to the recommendations was assessed using an abbreviated 2018 WCRF\/AICR score (range, 0\u20135\u00a0points). In the primary analysis, participants with a single incident cancer and who had a total abbreviated score were included (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a028,550). Associations between score and all\u2010cause mortality were investigated using multivariable Cox proportional hazards models. Analyses were conducted for all cancers combined and by site.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 28,550 individuals included in the primary analysis, 10,014 (35%) died over a 6\u2010year median follow\u2010up time. Abbreviated score was inversely associated with all\u2010cause mortality (hazard ratio, per 1\u2010point increment: 0.92; 95% confidence interval (CI), 0.90\u20130.94;\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). When considering individual cancer sites, significant inverse associations were observed for prostate, breast, lung, esophageal, and liver cancers, with risk reductions ranging from 5% to 14% per 1\u2010point increment in abbreviated score.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>This is the first study to investigate associations between adherence to the Cancer Prevention\u00a0Recommendations and cancer survival in a UK population. Each 1\u2010point increment in score, equivalent to fully meeting one recommendation, reduced risk of death from any cause by 8%, providing evidence for development of interventions to support compliance in people with cancer.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.70437","type":"journal-article","created":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T00:01:37Z","timestamp":1779926497000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Adherence to the 2018 World Cancer Research Fund\/American Institute for Cancer Research Cancer Prevention Recommendations and survival in people with incident cancer in UK Biobank"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5072-7644","authenticated-orcid":false,"given":"Fiona C.","family":"Malcomson","sequence":"first","affiliation":[{"name":"Human Nutrition &amp; Exercise Research Centre, Centre for Healthier Lives Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"},{"name":"Centre for Cancer Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Desy","family":"Nuryunarsih","sequence":"additional","affiliation":[{"name":"Centre for Cancer Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"},{"name":"NIHR Newcastle Patient Safety Research Collaboration Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8443-7327","authenticated-orcid":false,"given":"Solange","family":"Parra\u2010Soto","sequence":"additional","affiliation":[{"name":"Department of Nutrition and Public Health, Faculty of Health and Food Science Universidad del B\u00edo\u2010B\u00edo  Chill\u00e1n Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederick K.","family":"Ho","sequence":"additional","affiliation":[{"name":"School of Health and Wellbeing University of Glasgow  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Celis\u2010Morales","sequence":"additional","affiliation":[{"name":"School of Cardiovascular and Medical Sciences University of Glasgow  Glasgow UK"},{"name":"Human Performance Lab, Education, Physical Activity and Health Research Unit University Cat\u00f3lica del Maule  Talca Chile"},{"name":"High\u2010Altitude Medicine Research Centre (CEIMA) Universidad Arturo Prat  Iquique Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Sharp","sequence":"additional","affiliation":[{"name":"Centre for Cancer Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"},{"name":"NIHR Newcastle Patient Safety Research Collaboration Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Mathers","sequence":"additional","affiliation":[{"name":"Human Nutrition &amp; Exercise Research Centre, Centre for Healthier Lives Population Health Sciences Institute Newcastle University  Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Cancer Research Fund\/American Institute for Cancer Research. Diet Nutrition Physical Activity and Cancer: a Global Perspective. Continuous Update Project Expert Report 2018. 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