{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:11:56Z","timestamp":1788588716152,"version":"build-2803163510"},"reference-count":69,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer"],"published-print":{"date-parts":[[2026,9,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>Male breast cancer (MBC) is underrepresented in cancer statistics: this study aimed to assess the burden of MBC in Central, Eastern, and Western Europe from 1990 to 2023, using data from the Global Burden of Disease (GBD) Study 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Estimates from GBD 2023 were analyzed to determine the MBC incidence, mortality, and disability\u2010adjusted life years, their all\u2010ages and age\u2010standardized rates, and the 1990 through 2023 annual percent change. These estimates were compared to those for the GBD Super Regions and the Socio\u2010Demographic Index quintile countries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In Central Europe, age\u2010standardized incidence rates (ASIR) increased from 0.54 (0.40\u20130.76) to 1.05 (0.70\u20131.52), age\u2010standardized mortality rates (ASMR) from 0.29 (0.25\u20130.34) to 0.40 (0.36\u20130.45), and age\u2010standardized disability life\u2010year rates (ASDR) from 7.19 (6.15\u20138.41) to 9.63 (8.52\u201311.07). In Eastern Europe, ASIR remained relatively stable, changing from 0.81 (0.56\u20131.19) to 0.60 (0.38\u20130.92), whereas ASMR decreased from 0.40 (0.33\u20130.49) to 0.21 (0.16\u20130.25) and ASDR from 10.54 (8.69\u201312.89) to 5.55 (4.52\u20136.85). In Western Europe, ASIR increased from 0.47 (0.33\u20130.67) to 0.88 (0.59\u20131.24), whereas ASMR (0.22 [0.19\u20130.25] vs. 0.24 [0.21\u20130.27]) and ASDR (5.20 [4.49\u20135.97] vs. 5.75 [4.96\u20136.66]) remained stable.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The burden of MBC is increasing across Europe, particularly in the Central region, with huge regional differences. Population growth and variations over time impacted on the metrics. Even with a composite European scenario, the mortality\u2010to\u2010incidence ratio markedly declined in the three areas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncr.70585","type":"journal-article","created":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T11:26:26Z","timestamp":1787916386000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The burden of male breast cancer (MBC) in the GBD Central, Eastern, and Western Europe Regions from 1990 to 2023: Results from the Global Burden of Disease Study 2023"],"prefix":"10.1002","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3372-2248","authenticated-orcid":false,"given":"Roberto","family":"Passera","sequence":"first","affiliation":[{"name":"Department of Medical Sciences University of Torino  Torino Italy"},{"name":"Department of Imaging AOU Citt\u00e0 della Salute e della Scienza di Torino  Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Fabbro","sequence":"additional","affiliation":[{"name":"Institute for Research and Innovative Technologies Area Science Park  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Zamagni","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology and Public Health Research Unit Institute for Maternal and Child Health \u2013 IRCCS \u201cBurlo Garofolo\u201d  Trieste Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-254X(98)80011-3"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21871"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)01917-8"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)01330-3"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(16)30388\u20109"},{"key":"e_1_2_9_8_1","volume-title":"R: A language and environment for statistical computing","author":"R Core Team","year":"2017"},{"key":"e_1_2_9_9_1","unstructured":"The Institute for Health Metrics and Evaluation.Protocol for the Global Burden of Diseases Injuries and Risk Factors Study (GBD). 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