{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T00:55:51Z","timestamp":1760316951078,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T00:00:00Z","timestamp":1339459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cancer Cytopathology"],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>BACKGROUND:<\/jats:title><jats:p>Atypical glandular cells (AGC) on cervical cytology are high\u2013risk, requiring an extensive evaluation. Compliance with practice guidelines for AGC, however, has been low. Some AGC cytology reports contain cytopathologist recommendations for evaluation. This study determines whether evaluation rates for AGC have improved over time, and whether cytopathologists' recommendations correlate with the types of evaluation women receive.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS:<\/jats:title><jats:p>Evaluation rates from 284 women with AGC (2004\u20102007) were compared with findings from 1998\u20102001. Rates of evaluations were compared based on cytology report recommendations.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS:<\/jats:title><jats:p>A total of 76.1% of the AGC cases had histologic sampling, and 58.8% had a comprehensive evaluation. These rates are higher than those from 1998\u20102001 (63.5% and 35.8%, respectively; <jats:italic>P<\/jats:italic>&lt;.01). Rates of evaluations of women with AGC \u201cfavor neoplasia\u201d did not increase between the 2 time periods. Between 2004\u20102005 and 2006\u20102007, rates of comprehensive initial evaluations and endometrial sampling in women \u226535 years of age did not increase. Of the AGC reports that did contain cytopathologist recommendations, 28% were consistent with practice guidelines, 26% recommended an incomplete histologic evaluation, and 46% recommended repeat cytology. Women whose AGC report recommended a comprehensive evaluation or any histologic evaluation were more likely to have a comprehensive work\u2013up (79%) than those whose reports did not contain recommendations (55%, <jats:italic>P<\/jats:italic> &lt;0.01) or recommended repeat cytology (51%, <jats:italic>P<\/jats:italic>&lt;0.02).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS:<\/jats:title><jats:p>Adherence to practice guidelines for the evaluation of women with AGC has improved but continues to be suboptimal. Our findings suggest that continuing education and including practice guidelines on AGC cytology reports may improve compliance. Cancer (Cancer Cytopathol) 2013;121:47\u201353 \u00a9 2012 American Cancer Society.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncy.21211","type":"journal-article","created":{"date-parts":[[2012,6,12]],"date-time":"2012-06-12T14:35:33Z","timestamp":1339511733000},"page":"47-53","source":"Crossref","is-referenced-by-count":3,"title":["Adherence to practice guidelines for atypical glandular cells on cervical cytology"],"prefix":"10.1002","volume":"121","author":[{"given":"Kathryn E.","family":"Sharpless","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cara R.","family":"King","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter F.","family":"Schnatz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,6,12]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_6_2_2","DOI":"10.1097\/01.AOG.0000202401.29145.68"},{"doi-asserted-by":"publisher","key":"e_1_2_6_3_2","DOI":"10.1097\/01.AOG.0000152350.10875.02"},{"doi-asserted-by":"publisher","key":"e_1_2_6_4_2","DOI":"10.1001\/jama.287.16.2114"},{"doi-asserted-by":"publisher","key":"e_1_2_6_5_2","DOI":"10.1097\/LGT.0b013e3181585870"},{"doi-asserted-by":"publisher","key":"e_1_2_6_6_2","DOI":"10.1016\/j.ogc.2008.09.002"},{"doi-asserted-by":"publisher","key":"e_1_2_6_7_2","DOI":"10.1016\/j.ygyno.2009.05.019"},{"doi-asserted-by":"publisher","key":"e_1_2_6_8_2","DOI":"10.1016\/S0029-7844(03)00565-9"},{"doi-asserted-by":"publisher","key":"e_1_2_6_9_2","DOI":"10.1067\/mob.2001.116725"},{"doi-asserted-by":"publisher","key":"e_1_2_6_10_2","DOI":"10.1097\/01.AOG.0000218705.87329.4a"},{"doi-asserted-by":"publisher","key":"e_1_2_6_11_2","DOI":"10.1097\/01.AOG.0000153489.25288.c1"},{"unstructured":"PreacherK. Calculation for the chi\u2013square test: an interactive calculation tool for chi\u2013square tests of goodness of fit and independence.http:\/\/www.quantpsy.orgAccessed April 14 2010.","key":"e_1_2_6_12_2"},{"doi-asserted-by":"publisher","key":"e_1_2_6_13_2","DOI":"10.17226\/1626"},{"doi-asserted-by":"publisher","key":"e_1_2_6_14_2","DOI":"10.1097\/LGT.0b013e318183a438"},{"doi-asserted-by":"publisher","key":"e_1_2_6_15_2","DOI":"10.1097\/LGT.0b013e318183bb0e"},{"key":"e_1_2_6_16_2","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1097\/AOG.0b013e3181c799a3","article-title":"Relationship of atypical glandular cell cytology, age, and human papillomavirus detection to cervical and endometrial cancer risks","volume":"115","author":"Castle PE","journal-title":"Obstet Gynecol"},{"doi-asserted-by":"publisher","key":"e_1_2_6_17_2","DOI":"10.1002\/dc.10284"},{"key":"e_1_2_6_18_2","first-page":"1113","article-title":"Follow\u2013up of abnormal gynecologic cytology. A College of American Pathologists Q\u2013Probes Study of 16,312 cases from 306 laboratories","volume":"124","author":"Austin RM","year":"2000","journal-title":"Arch Pathol Lab Med."},{"key":"e_1_2_6_19_2","first-page":"665","article-title":"Follow\u2013up of abnormal gynecologic cytology: a college of American pathologists Q\u2013probes study of 16132 cases from 306 laboratories","volume":"124","author":"Jones BA","year":"2000","journal-title":"Arch Pathol Lab Med."},{"doi-asserted-by":"publisher","key":"e_1_2_6_20_2","DOI":"10.1097\/PCR.0b013e31820fff8a"},{"doi-asserted-by":"publisher","key":"e_1_2_6_21_2","DOI":"10.1001\/jama.287.16.2120"},{"key":"e_1_2_6_22_2","first-page":"645","article-title":"Management of abnormal cervical cytology and histology","volume":"106","author":"American College of Obstetricians and Gynecologists Practice Bulletin No. 66","year":"2005","journal-title":"Obstet Gynecol."},{"doi-asserted-by":"publisher","key":"e_1_2_6_23_2","DOI":"10.1097\/AOG.0b013e318192497c"}],"container-title":["Cancer Cytopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcncy.21211","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cncy.21211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T20:33:25Z","timestamp":1760301205000},"score":1,"resource":{"primary":{"URL":"https:\/\/acsjournals.onlinelibrary.wiley.com\/doi\/10.1002\/cncy.21211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6,12]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,1]]}},"alternative-id":["10.1002\/cncy.21211"],"URL":"https:\/\/doi.org\/10.1002\/cncy.21211","archive":["Portico"],"relation":{},"ISSN":["1934-662X","1934-6638"],"issn-type":[{"type":"print","value":"1934-662X"},{"type":"electronic","value":"1934-6638"}],"subject":[],"published":{"date-parts":[[2012,6,12]]}}}