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This review deals with the cytological features of such tumors including aggressive variants of papillary thyroid carcinoma, poorly differentiated thyroid carcinoma, and anaplastic thyroid carcinoma. These malignancies fall into 2 groups based on their cytomorphology: those that exhibit distinct microscopic features (eg, nuclear findings typical of classical papillary thyroid carcinoma or marked anaplasia) and those that present with more subtle cytologic features (eg, nuclear pseudostratification, \u201csoap bubble\u201d nuclei, supranuclear or subnuclear cytoplasmic vacuoles, rosette\u2010like structures, hobnail cells). We review the literature regarding these aggressive thyroid cancers and highlight important phenotypic characteristics that can be useful for their diagnosis based on fine needle aspiration.<\/jats:p>","DOI":"10.1002\/cncy.22136","type":"journal-article","created":{"date-parts":[[2019,5,31]],"date-time":"2019-05-31T09:10:14Z","timestamp":1559293814000},"page":"432-446","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":46,"title":["Cytologic features of aggressive variants of follicular\u2010derived thyroid carcinoma"],"prefix":"10.1002","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3819-4229","authenticated-orcid":false,"given":"Esther Diana","family":"Rossi","sequence":"first","affiliation":[{"name":"Division of Anatomic Pathology and Histology Catholic University of Sacred Heart Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William 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