{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T17:04:39Z","timestamp":1792515879751,"version":"4.5.0"},"reference-count":49,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T00:00:00Z","timestamp":1565136000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Cytopathology"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The scarcity of updated data on the prevalence of cervical human papillomavirus (HPV) infection in the Gulf Cooperation Council (GCC) countries hampers the establishment of cervical cancer screening and HPV vaccination programs. The current study estimated the prevalence of cervical high\u2010risk (HR) HPV infection among women residing in some countries of the GCC and analyzed the correlation between HR\u2010HPV infection types and cytology results.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In total, 2478 women residing in the Kingdom of Saudi Arabia, Qatar, the United Arab Emirates, and Bahrain were enrolled in this study. Cervical specimens were subjected to simultaneous liquid\u2010based cytology and HR\u2010HPV DNA analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 2478 women, 520 (21%) tested positive for HR\u2010HPV. Other non\u2010HPV genotype 16 (HPV16)\/HPV18 HR\u2010HPV was the most frequently detected infection type, accounting for 63.7%. Non\u2010Arab women had a significantly higher HR\u2010HPV positivity rate compared with Arab women (31.6% vs 16.4%;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). The HR\u2010HPV positivity rate was highest among women residing in Qatar (31.3%), followed by women living in Bahrain (20%), the Kingdom of Saudi Arabia (17.2%), and the United Arab Emirates (14.7%). The overall prevalence of HR\u2010HPV infections declined significantly with advancing age (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). Women with abnormal cytology had a significantly higher HR\u2010HPV positivity rate than those with normal cytology (50.6% vs 14.7%;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a0.001). The HR\u2010HPV positivity rate increased as the severity of the cytological lesion increased.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The current study provides updated data on HR\u2010HPV prevalence in the GCC countries and delivers an evidence base for supporting the introduction of regional\/national vaccination and screening programs in these countries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/cncy.22165","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T11:44:05Z","timestamp":1565178245000},"page":"567-577","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Cervical high\u2010risk human papillomavirus infection among women residing in the Gulf Cooperation Council countries: Prevalence, type\u2010specific distribution, and correlation with cervical cytology"],"prefix":"10.1002","volume":"127","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8217-0262","authenticated-orcid":false,"given":"Mohamed A. 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