{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T17:57:01Z","timestamp":1793469421342,"version":"4.5.0"},"reference-count":34,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T00:00:00Z","timestamp":1593388800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["acsjournals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cancer Cytopathology"],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>In the United States, the rate of cervical cancer is disproportionally higher in Hispanic and Black women compared with White women. In the current study, the authors compared human papillomavirus (HPV) testing and cytology results among Black and White women over a 24\u2010month period. They then assessed the rates in young women in 2011 compared with 2017 according to race.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The authors searched the gynecologic cytology case files for Black and White women treated at Johns Hopkins Hospital across all ages for a period of 24 months (2017\u20102019) and compared HPV results and cytologic interpretations. They then compared results among Black and White cohorts of young women (aged 21\u201029 years) in 2011 versus 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 26,302 specimens from January 2017 to January 2019, including 11,676 Black women and 14,626 White women, were reviewed. The most common HPV genotype(s) detected were non\u2013HPV\u201016 and\/or HPV\u201018 (non\u201016\/18) high\u2010risk HPV (hrHPV) (84% of positive results). Non\u201016\/18 hrHPV was more common in Black women (1309 women; 15%) compared with White women (1075 women; 9%). Non\u201016\/18 hrHPV was more commonly observed in association with atypical squamous cells, cannot rule out high\u2010grade squamous intraepithelial lesion and\/or high\u2010grade squamous intraepithelial lesion (ASC\u2010H\/HSIL) in HPV\u2010positive Black women compared with White women (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.007). Black women were found to have higher rates of HPV\u2010positive Papanicolaou results and high\u2010grade lesions, including carcinoma (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.01). In the 2011 cohort, young Black women were found to have a higher rate of ASC\u2010H\/HSIL (<jats:italic>P<\/jats:italic>\u00a0=\u00a0.003) compared with White women. However, the difference was not noted in the 2017 cohort. There was a decrease in ASC\u2010H\/HSIL in 2017 compared with 2011, with a lower incidence of ASC\u2010H\/HSIL noted among Black women in 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Black women appear to have a higher incidence of higher grade lesions, but the difference between Black and White cohorts was not found to be significant in young women in more recent years.<\/jats:p><\/jats:sec>","DOI":"10.1002\/cncy.22316","type":"journal-article","created":{"date-parts":[[2020,6,29]],"date-time":"2020-06-29T10:28:25Z","timestamp":1593426505000},"page":"860-869","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Health disparities in cervical cancer: Prevalence of high\u2010risk HPV and cytologic diagnoses according to race"],"prefix":"10.1002","volume":"128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2104-4614","authenticated-orcid":false,"given":"Daniel","family":"Miller","sequence":"first","affiliation":[{"name":"Department of Pathology The Johns Hopkins Hospital Baltimore Maryland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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