{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T15:22:58Z","timestamp":1791213778303,"version":"4.1.0"},"reference-count":127,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2003,6,25]],"date-time":"2003-06-25T00:00:00Z","timestamp":1056499200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2003,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The advance of knowledge of the thalamic reticular nucleus and its connections has been reviewed and Max Cowan's contributions to this knowledge and to the methods used for studying the nucleus have been summarized. Whereas 50 years ago the nucleus was seen as a diffusely organized cell group closely related to the brain stem reticular formation, it can now be seen as a complex, tightly organized entity that has a significant inhibitory, modulatory action on the thalamic relay to cortex. The nucleus is under the control, on the one hand, of topographically organized afferents from the cerebral cortex and the thalamus, and on the other of more diffuse afferents from brain stem, basal forebrain, and other regions. Whereas the second group of afferents can be expected to have global actions on thalamocortical transmission, relevant for overall attentive state, the former group will have local actions, modulating transmission through the thalamus to cortex with highly specific local effects. Since it appears that all areas of cortex and all parts of the thalamus are linked directly to the reticular nucleus, it now becomes important to define how the several pathways that pass through the thalamus relate to each other in their reticular connections. J. Comp. Neurol. 463:360\u2013371, 2003. \u00a9 2003 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.10738","type":"journal-article","created":{"date-parts":[[2004,10,22]],"date-time":"2004-10-22T01:07:27Z","timestamp":1098407247000},"page":"360-371","source":"Crossref","is-referenced-by-count":180,"title":["Structure and connections of the thalamic reticular nucleus: Advancing views over half a century"],"prefix":"10.1002","volume":"463","author":[{"given":"R.W.","family":"Guillery","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John K.","family":"Harting","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,6,25]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(85)90125-3"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1997.tb01391.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1984.sp015085"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00238961"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.12.4746"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903190209"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00227337"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903020112"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)90188-9"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903480402"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9861(20000904)424:4<701::AID-CNE11>3.0.CO;2-B"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(95)00009-8"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1995.tb01016.x"},{"key":"e_1_2_5_15_1","volume-title":"Neurological anatomy in relation to clinical medicine","author":"Brodal A","year":"1948"},{"key":"e_1_2_5_16_1","volume-title":"Neurological anatomy in relation to clinical medicine","author":"Brodal A","year":"1981"},{"key":"e_1_2_5_17_1","doi-asserted-by":"crossref","DOI":"10.1093\/oso\/9780195074017.001.0001","volume-title":"Histology of the nervous system of man and vertebrates","author":"Cajal S","year":"1995"},{"key":"e_1_2_5_18_1","first-page":"587","article-title":"Cortical connexions of the thalamic reticular nucleus","volume":"98","author":"Carman J","year":"1964","journal-title":"J Anat"},{"key":"e_1_2_5_19_1","first-page":"140","volume-title":"The neural basis of visual function","author":"Chalupa LM","year":"1991"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900970105"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00608242"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903220203"},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1996.tb01222.x"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1990.tb00414.x"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1991.tb00044.x"},{"key":"e_1_2_5_26_1","first-page":"78","article-title":"The thalamic projections upon the telencephalon in the pigeon (Columba livia)","volume":"95","author":"Cowan WM","year":"1961","journal-title":"J Anat"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(72)90344-7"},{"key":"e_1_2_5_28_1","doi-asserted-by":"crossref","first-page":"6694","DOI":"10.1523\/JNEUROSCI.19-15-06694.1999","article-title":"Glutamate inhibits thalamic reticular neurons","volume":"19","author":"Cox CL","year":"1999","journal-title":"J Neurosci"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960311)366:3<416::AID-CNE4>3.0.CO;2-7"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.16.8854"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1992.tb00159.x"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1992.tb00160.x"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960304)366:2<207::AID-CNE2>3.0.CO;2-9"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19980112)390:2<167::AID-CNE1>3.0.CO;2-#"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-19-08754.2002"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1989.tb00777.x"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/1603"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.81.14.4586"},{"key":"e_1_2_5_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903100304"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903340409"},{"key":"e_1_2_5_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1996.tb01217.x"},{"key":"e_1_2_5_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903190108"},{"key":"e_1_2_5_43_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1002\/(SICI)1096-9861(19980808)395:3<281::AID-CNE2>3.0.CO;2-Z","article-title":"Corticocortical communication via the thalamus: ultrastructural studies of corticothalamic projections from area 17 to the lateral posterior nucleus and inferior pulvinar of the owl monkey","volume":"95","author":"Feig S","year":"1998","journal-title":"J Comp Neurol"},{"key":"e_1_2_5_44_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1981.46.1.80"},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523898154111"},{"key":"e_1_2_5_46_1","first-page":"583","article-title":"Anatomical evidence concerning the role of the thalamus in corticocortical communication: a brief review","volume":"187","author":"Guillery RW","year":"1995","journal-title":"J Anat"},{"key":"e_1_2_5_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(01)00582-7"},{"key":"e_1_2_5_48_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2002.1171"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902780403"},{"key":"e_1_2_5_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902620109"},{"key":"e_1_2_5_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903100310"},{"key":"e_1_2_5_52_1","doi-asserted-by":"publisher","DOI":"10.5962\/bhl.title.6375"},{"key":"e_1_2_5_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00228517"},{"key":"e_1_2_5_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)90925-7"},{"key":"e_1_2_5_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902100402"},{"key":"e_1_2_5_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901620302"},{"key":"e_1_2_5_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4615-1749-8"},{"key":"e_1_2_5_58_1","volume-title":"Principles of neural science","author":"Kandel ER","year":"2000"},{"key":"e_1_2_5_59_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18-22-09500.1998"},{"key":"e_1_2_5_60_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-03-01002.2002"},{"key":"e_1_2_5_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902030204"},{"key":"e_1_2_5_62_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19991108)414:1<67::AID-CNE6>3.0.CO;2-Z"},{"key":"e_1_2_5_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903520203"},{"key":"e_1_2_5_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903410408"},{"key":"e_1_2_5_65_1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1002\/cne.903580206","article-title":"Organization of connections between the thalamic reticular and the anterior thalamic nucleus in the rat","volume":"358","author":"Lozs\u00e1di DA","year":"1995","journal-title":"J Comp Neurol"},{"key":"e_1_2_5_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1996.tb01205.x"},{"key":"e_1_2_5_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960916)373:2<271::AID-CNE9>3.0.CO;2-0"},{"key":"e_1_2_5_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901460104"},{"key":"e_1_2_5_69_1","first-page":"145","article-title":"Transneuronal cell degeneration in the lateral geniculate nucleus of the macaque monkey","volume":"94","author":"Matthews MR","year":"1960","journal-title":"J Anat"},{"key":"e_1_2_5_70_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-23-08897.2000"},{"key":"e_1_2_5_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(92)90012-4"},{"key":"e_1_2_5_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237870"},{"key":"e_1_2_5_73_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00248531"},{"key":"e_1_2_5_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(98)00632-0"},{"key":"e_1_2_5_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(00)02182-X"},{"key":"e_1_2_5_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(81)90102-0"},{"key":"e_1_2_5_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237447"},{"key":"e_1_2_5_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(77)90681-3"},{"key":"e_1_2_5_79_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-02-00845.2000"},{"key":"e_1_2_5_80_1","doi-asserted-by":"publisher","DOI":"10.3109\/10520295409115448"},{"key":"e_1_2_5_81_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn0602-517"},{"key":"e_1_2_5_82_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901880113"},{"key":"e_1_2_5_83_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01217752"},{"key":"e_1_2_5_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(90)91832-2"},{"key":"e_1_2_5_85_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.1998.00362.x"},{"key":"e_1_2_5_86_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19980209)391:2<180::AID-CNE3>3.0.CO;2-Z"},{"key":"e_1_2_5_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.1995.tb01017.x"},{"key":"e_1_2_5_88_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(94)01303-Y"},{"key":"e_1_2_5_89_1","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.1523\/JNEUROSCI.17-09-03215.1997","article-title":"Dendrodendritic and axoaxonic synapses in the thalamic reticular nucleus of the adult rat","volume":"17","author":"Pinault D","year":"1997","journal-title":"J Neurosci"},{"key":"e_1_2_5_90_1","first-page":"489","article-title":"The origin of the mammillothalamic tract in the rat","volume":"88","author":"Powell TPS","year":"1954","journal-title":"J Anat"},{"key":"e_1_2_5_91_1","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1136\/jnnp.18.4.266","article-title":"The projection of the midline and intralaminar nuclei of the thalamus of the rabbit","volume":"18","author":"Powell TPS","year":"1955","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"e_1_2_5_92_1","first-page":"269","article-title":"An experimental study of the projection of the cochlea","volume":"96","author":"Powell TPS","year":"1962","journal-title":"J Anat"},{"key":"e_1_2_5_93_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902880412"},{"key":"e_1_2_5_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901730211"},{"key":"e_1_2_5_95_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19980126)390:4<515::AID-CNE5>3.0.CO;2-3"},{"key":"e_1_2_5_96_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900770105"},{"key":"e_1_2_5_97_1","first-page":"455","article-title":"The cortical connections of the reticular complex of the thalamus","volume":"30","author":"Rose JE","year":"1952","journal-title":"Res Publ Assn Nerv Ment Dis"},{"key":"e_1_2_5_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(95)00047-X"},{"key":"e_1_2_5_99_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-22-08880.1997"},{"key":"e_1_2_5_100_1","doi-asserted-by":"crossref","first-page":"8894","DOI":"10.1523\/JNEUROSCI.17-22-08894.1997","article-title":"Inhibitory interactions between perigeniculate GABAergic neurons","volume":"17","author":"Sanchez\u2010Vives MV","year":"1997","journal-title":"J Neurosci"},{"key":"e_1_2_5_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(66)90104-1"},{"key":"e_1_2_5_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903090302"},{"key":"e_1_2_5_103_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523800007446"},{"key":"e_1_2_5_104_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1996.76.3.1367"},{"key":"e_1_2_5_105_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.12.7121"},{"key":"e_1_2_5_106_1","volume-title":"Exploring the thalamus","author":"Sherman SM","year":"2001"},{"key":"e_1_2_5_107_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2002.1161"},{"key":"e_1_2_5_108_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00850.2001"},{"key":"e_1_2_5_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903040311"},{"key":"e_1_2_5_110_1","first-page":"105","article-title":"Corticothalamic networks oscillations and plasticity","volume":"77","author":"Steriade M","year":"1998","journal-title":"Adv Neurol"},{"key":"e_1_2_5_111_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.06-01-00068.1986"},{"key":"e_1_2_5_112_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8235588"},{"key":"e_1_2_5_113_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-17-07766.2002"},{"key":"e_1_2_5_114_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901810304"},{"key":"e_1_2_5_115_1","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0079-6123(08)63614-6","article-title":"GABAergic circuits in the lateral geniculate nucleus of the cat","volume":"90","author":"Uhlrich DJ","year":"1992","journal-title":"Prog Brain Res"},{"key":"e_1_2_5_116_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.08-12-04565.1988"},{"key":"e_1_2_5_117_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1991.65.6.1528"},{"key":"e_1_2_5_118_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10568"},{"key":"e_1_2_5_119_1","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1126\/science.1734518","article-title":"Information processing in the primate visual system: an integrated systems perspective","volume":"225","author":"Van Essen DC","year":"1992","journal-title":"Science"},{"key":"e_1_2_5_120_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8392750"},{"key":"e_1_2_5_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002210050744"},{"key":"e_1_2_5_122_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.1389"},{"key":"e_1_2_5_123_1","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1152\/jn.1994.72.4.1993","article-title":"Oscillatory synaptic interactions between ventroposterior and reticular neurons in mouse thalamus in vitro","volume":"72","author":"Warren RA","year":"1994","journal-title":"J Neurophysiol"},{"key":"e_1_2_5_124_1","doi-asserted-by":"crossref","first-page":"10135","DOI":"10.1523\/JNEUROSCI.19-22-10135.1999","article-title":"Attentional orienting is impaired by unilateral lesions of the thalamic reticular nucleus in the rat","volume":"19","author":"Weese GD","year":"1999","journal-title":"J Neurosci"},{"key":"e_1_2_5_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(93)91207-9"},{"key":"e_1_2_5_126_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903490203"},{"key":"e_1_2_5_127_1","doi-asserted-by":"crossref","first-page":"2254","DOI":"10.1523\/JNEUROSCI.05-08-02254.1985","article-title":"The morphology of physiologically identified GABAergic neurons in the somatic sensory part of the thalamic reticular nucleus in the cat","volume":"5","author":"Yen CT","year":"1985","journal-title":"J Neurosci"},{"key":"e_1_2_5_128_1","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1523\/JNEUROSCI.05-05-01316.1985","article-title":"Morphological and functional types of neurons in cat ventral posterior thalamic nucleus","volume":"5","author":"Yen CT","year":"1985","journal-title":"J Neurosci"}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.10738","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.10738","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T18:25:48Z","timestamp":1705256748000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.10738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6,25]]},"references-count":127,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,9]]}},"alternative-id":["10.1002\/cne.10738"],"URL":"https:\/\/doi.org\/10.1002\/cne.10738","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6,25]]}}}