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Here, we studied the effects of nimodipine in a different injury model in which the facial nerve was unilaterally crushed intracranially. This lesion caused complete anterograde degeneration and partial retrograde degeneration that were studied with a combination of several stereological methods. Nimodipine did not attenuate the modest lesion\u2010induced neuronal loss (13%) but accelerated the time course of functional recovery and axonal regrowth, inducing increased numbers and sizes of myelinated axons in the facial nerve. It is interesting to note that nimodipine also enlarged the axons and the myelin sheaths in the nonlesioned facial nerve, which points to the possibility of using this substance for new clinical applications to promote axonal growth and remyelination. J. Comp. Neurol. 437:106\u2013117, 2001. \u00a9 2001 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.1273","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T17:50:36Z","timestamp":1030297836000},"page":"106-117","source":"Crossref","is-referenced-by-count":62,"title":["Nimodipine promotes regeneration and functional recovery after intracranial facial nerve crush"],"prefix":"10.1002","volume":"437","author":[{"given":"Per","family":"Mattsson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann 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