{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T15:06:27Z","timestamp":1790435187592,"version":"4.1.0"},"reference-count":78,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2001,12,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Previous studies have suggested the presence of numerous catecholamine\u2010containing cells in both the central ganglia and peripheral tissues of\n                    <jats:italic>Aplysia<\/jats:italic>\n                    , but they often offered conflicting or incomplete accounts of numbers, locations, and morphologies. The current study combines aldehyde\u2010induced histofluorescence and tyrosine hydroxylase\u2010like immunoreactivity together with confocal microscopy to provide details of these cells. Approximately 35\u201350 neurones in the cerebral ganglia, 4\u20138 neurones in the pedal ganglia, 5 neurones in the buccal ganglia, and numerous small fibres in various nerve trunks exhibited both immunoreactivity and aldehyde\u2010induced fluorescence. Approximately 20 cells in the pedal ganglia and 4 cells in the buccal ganglia exhibited only immunoreactivity whereas 15\u201320 neurons in the cerebral ganglia exhibited only aldehyde\u2010induced fluorescence. No somata in the pleural or abdominal ganglia exhibited aldehyde\u2010induced fluorescence or immunoreactivity. Both aldehyde\u2010induced histofluorescence and immunoreactivity also labelled what appeared to be two classes of catecholamine\u2010containing cells in the gill, siphon, oesophagus, rhinophore, tentacle, and reproductive organs. The more numerous, but smaller cells had subepithelial somata and processes penetrating the overlying body wall, thus suggesting a sensory function. Another class of neurones had larger somata, often located more deeply within the tissue, and occasionally appeared to be multipolar. Processes from these various peripheral cells appeared to comprise the major component of afferent fibres and to form an extensive peripheral plexus, often associated with various muscles. The morphologies of the peripheral cells thus suggest involvement in both local and centrally mediated reflexes and responses, but additional studies must test such hypothesised functions and determine the sensory modalities that the cells mediate. J. Comp. Neurol. 441:91\u2013105, 2001. \u00a9 2001 Wiley\u2010Liss, Inc.\n                  <\/jats:p>","DOI":"10.1002\/cne.1399","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T17:18:31Z","timestamp":1030295911000},"page":"91-105","source":"Crossref","is-referenced-by-count":46,"title":["Catecholamine\u2010containing cells in the central nervous system and periphery of\n                    <i>Aplysia californica<\/i>"],"prefix":"10.1002","volume":"441","author":[{"given":"Roger P.","family":"Croll","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2001,11]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1972.sp009933"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6773(75)92066-0"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1152\/jn.1979.42.2.530","article-title":"Cellular studies of peripheral neurons in siphon skin of Aplysia californica","volume":"42","author":"Bailey CH","year":"1976","journal-title":"J Neurophysiol"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6828885"},{"key":"e_1_2_6_6_1","first-page":"399","volume-title":"Goodman and Gilman's pharmacological basis of therapeutics","author":"Baldessarini RJ","year":"1996"},{"key":"e_1_2_6_7_1","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1101\/lm.5.3.204","article-title":"Multiple memory processes following training that a food is inedible in Aplysia","volume":"5","author":"Botzer D","year":"1998","journal-title":"Learn Mem"},{"key":"e_1_2_6_8_1","volume-title":"Structure and function in the nervous systems of invertebrates","author":"Bulloch TH","year":"1965"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.214854"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1139\/z79-085"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1101\/lm.2.3-4.133"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"5988","DOI":"10.1523\/JNEUROSCI.18-15-05988.1998","article-title":"Cellular correlates of long\u2010term sensitization in Aplysia","volume":"18","author":"Cleary LJ","year":"1998","journal-title":"J Neurosci"},{"key":"e_1_2_6_13_1","first-page":"225","article-title":"Humoral factors released during trauma of Aplysia body wall. 2","volume":"159","author":"Cooper BF","year":"1989","journal-title":"Effects of possible mediators. 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