{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T01:15:49Z","timestamp":1788570949405,"version":"build-2803163510"},"reference-count":72,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2002,3,22]],"date-time":"2002-03-22T00:00:00Z","timestamp":1016755200000},"content-version":"vor","delay-in-days":165,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2001,10,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The interstitial nucleus of the posterior limb of the anterior commissure (IPAC) lies at the junction of the striatopallidal system and the lateral bed nucleus of the stria terminalis\u2010central amygdaloid nucleus continuum (i.e., the central extended amygdala; EAc). Its efferent connections were investigated in the rat with anterograde (\n                    <jats:italic>Phaseolus vulgaris<\/jats:italic>\n                    leucoagglutinin) and retrograde (Fluoro\u2010Gold and cholera toxin B subunit) tracers and compared with those of the central amygdaloid nucleus. Our anterograde tracing experiments reveal that the projections of the medial IPAC largely reciprocate its afferent connections (Shammah\u2010Lagnado et al. [\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"#bib62\">1999<\/jats:ext-link>\n                    ] Neuroscience 94:1097\u20131123) and are very similar to those of the medial part of the central amygdaloid nucleus. The lateral IPAC, on the other hand, innervates the pallidal complex, substantia nigra and retrorubral field. Local connections are found within medial IPAC and within lateral IPAC, but the two divisions are not interconnected. Our retrograde tracing experiments confirm that IPAC projections to EAc components, parabrachial area, and nucleus of the solitary tract originate chiefly from the medial division, whereas both medial and lateral divisions innervate the retrorubral field. Moreover, in sections processed for choline acetyltransferase, the strong projections from caudal IPACm to the posterior basolateral amygdaloid nucleus and the amygdalopiriform transition area were found to arise chiefly from cholinergic cells. Overall, our results suggest that the medial IPAC is intimately related to the EAc, whereas the lateral IPAC represents a striatal territory. J. Comp. Neurol. 439:104\u2013126, 2001. \u00a9 2001 Wiley\u2010Liss, Inc.\n                  <\/jats:p>","DOI":"10.1002\/cne.1999","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T08:27:22Z","timestamp":1033892842000},"page":"104-126","source":"Crossref","is-referenced-by-count":73,"title":["Striatal and central extended amygdala parts of the interstitial nucleus of the posterior limb of the anterior commissure: Evidence from tract\u2010tracing techniques in the rat"],"prefix":"10.1002","volume":"439","author":[{"given":"Sara J.","family":"Shammah\u2010Lagnado","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George 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