{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T03:26:02Z","timestamp":1789615562662,"version":"build-2803163510"},"reference-count":56,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,4,15]],"date-time":"2004-04-15T00:00:00Z","timestamp":1081987200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2004,5,24]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We have studied the organization of the midbrain radial glia in embryos of <jats:italic>Gallotia galloti<\/jats:italic> using the fluorescent lipophilic dye 1,1\u2032\u2010dioctadecyl\u20103,3,3\u2032,3\u2032\u2010tetramethyl\u2010indocarbocyanine perchlorate (DiI) and the antibodies H5 and RC2. Our goal was to verify if the radial glia takes part in the midbrain boundaries formation and if it defines different zones. Our exam reveals two clear limits, anterior or mesencephalic\u2013diencephalic (m\/d) and posterior or mesencephalic\u2013rhombencephalic (m\/r), that can be defined as the borders where the midbrain radial glia processes end. Moreover, fasciculate radial glia processes characterize these limits totally or partially. They coincide with gene expression limits and with cytoarchitectonic limits defined by other criteria. Six different subdivisions, five alar and one basal, can be defined according to radial glia distribution, fasciculation, and immunohistochemical features. The ventral part of the alar region is defined by an RC2\u2010positive bundle of radial glial cells. This bundle supposes a trustworthy landmark to point out the tectal\/tegmental boundary. We hypothesize that this pattern of midbrain radial glia represents a basic model in amniota. J. Comp. Neurol. 473:162\u2013176, 2004. \u00a9 2004 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.20078","type":"journal-article","created":{"date-parts":[[2004,4,15]],"date-time":"2004-04-15T19:01:50Z","timestamp":1082055710000},"page":"162-176","source":"Crossref","is-referenced-by-count":3,"title":["Radial glia defines boundaries and subdivisions in the embryonic midbrain of the lizard <i>Gallotia galloti<\/i>"],"prefix":"10.1002","volume":"473","author":[{"given":"Carmen Ma.","family":"Trujillo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen","family":"Damas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,4,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1058624"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.00179"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"5127","DOI":"10.1242\/dev.126.22.5127","article-title":"Engrailed defines the position of dorsal di\u2010mesencephalic boundary by repressing diencephalic fate","volume":"126","author":"Araki J","year":"1999","journal-title":"Development"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1463-6395.1953.tb00370.x"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901000308"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000147278"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.121.2.439"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011067918585"},{"key":"e_1_2_6_10_1","first-page":"309","article-title":"Table du d\u00e9veloppement du l\u00e9zard vivipare (Lacerta vivipara)","volume":"50","author":"Dufaure JP","year":"1961","journal-title":"Arch Anat Microsc Morphol Exp"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-4388(03)00013-8"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902690103"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(01)00723-7"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/39453"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80621-2"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.2000.9962"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.22.1.511"},{"key":"e_1_2_6_18_1","first-page":"367","article-title":"The embryological development of primary visual centres in the turtle Emys orbicularis","volume":"183","author":"Hergueta S","year":"1993","journal-title":"J Anat"},{"key":"e_1_2_6_19_1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/aja.1002040308","article-title":"Cell and matrix specializations of rhombomere boundaries","volume":"204","author":"Heyman I","year":"1993","journal-title":"Dev Dyn"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004290050079"},{"key":"e_1_2_6_21_1","first-page":"865","volume-title":"The comparative anatomy of the nervous system of vertebrates including man","author":"Kappers CUA","year":"1967"},{"key":"e_1_2_6_22_1","first-page":"1","article-title":"The development of the diencephalon of the Chinese hamster. 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