{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,6]],"date-time":"2024-10-06T00:34:50Z","timestamp":1728174890080},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2006,7,19]],"date-time":"2006-07-19T00:00:00Z","timestamp":1153267200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2006,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Cholinergic basal forebrain neurons confined within the intrinsic connections of the extended amygdala in the caudal sublenticular region and anterior amygdaloid area (cSLR\/AAA) differ from other basal forebrain cholinergic neurons in several morphological and neurochemical respects. These cSLR\/AAA cholinergic neurons have been subjected to additional investigations described in this report. First, fibers traced anterogradely following injections of <jats:italic>Phaseolus vulgaris\u2010<\/jats:italic>leucoagglutinin in the central amygdaloid nucleus were shown to contact cSLR\/AAA cholinergic neurons and dendrites. Second, these neurons were shown to be contacted by numerous GABAergic boutons with symmetric synaptic specializations. Third, the numbers of synaptic densities of morphologically characterized symmetric contacts on the somata and proximal dendrites of cSLR\/AAA cholinergic neurons were shown to significantly exceed those of extra\u2010cSLR\/AAA cholinergic neurons. Fourth, fine structural features distinguishing cSLR\/AAA cholinergic neurons from other basal forebrain cholinergic neurons were revealed. Specifically, cSLR\/AAA cholinergic neurons have less abundant cytoplasm and a less well\u2010organized system of rough endoplasmic reticulum than their counterparts in other parts of the basal forebrain. Thus, morphologically and neurochemically distinct cSLR\/AAA cholinergic neurons exhibit robust proximal inhibitory inputs, of which a significant number originate in the extended amygdala, while cholinergic neurons outside this region lack a substrate for strong proximal inhibitory input. The implications of these findings for interaction of fear, anxiety, and attention are considered. J. Comp. Neurol. 498:93\u2013111, 2006. \u00a9 2006 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.21044","type":"journal-article","created":{"date-parts":[[2006,7,21]],"date-time":"2006-07-21T07:36:47Z","timestamp":1153467407000},"page":"93-111","source":"Crossref","is-referenced-by-count":12,"title":["Synaptologic and fine structural features distinguishing a subset of basal forebrain cholinergic neurons embedded in the dense intrinsic fiber network of the caudal extended amygdala"],"prefix":"10.1002","volume":"498","author":[{"given":"Louise D.","family":"Loopuijt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel S.","family":"Zahm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,7,19]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(88)90217-5"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/199655a0"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902500108"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.6.2115"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902340203"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903020413"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(68)90234-5"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903060408"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01611861"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1625"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.1040"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(02)03513-8"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19961028)374:4<555::AID-CNE6>3.0.CO;2-0"},{"key":"e_1_2_5_15_1","first-page":"420","article-title":"Axo\u2010somatic and axo\u2010dendritic synapses of the cerebral cortex: an electron microscopic study","volume":"93","author":"Gray EG","year":"1959","journal-title":"J Anat"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10279"},{"key":"e_1_2_5_17_1","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1523\/JNEUROSCI.14-03-01271.1994","article-title":"Complete and selective cholinergic denervation of rat neocortex and hippocampus but not amygdala by an immunotoxin against the p75 NGF receptor","volume":"14","author":"Heckers S","year":"1994","journal-title":"J Neurosci"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902390205"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902730210"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(01)00578-4"},{"key":"e_1_2_5_21_1","series-title":"Consciousness: at the frontiers of neuroscience, advances in neurology","first-page":"75","author":"Jones BE","year":"1998"},{"key":"e_1_2_5_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1991.tb08211.x"},{"key":"e_1_2_5_23_1","volume-title":"Quantitative ultrastructural analysis of the synaptic input to corticopetal cholinergic neurons in the caudal sublenticular region\/anterior amygdaloid area and other basal forebrain regions","author":"Loopuijt LD","year":"2004"},{"key":"e_1_2_5_24_1","volume-title":"An electron microscopic immunohistochemical study of projections from the extended amygdala to cholinergic basal forebrain neurons in the caudal sublenticular region\/anterior amygdaloid area in the rat","author":"Loopuijt LD","year":"2005"},{"key":"e_1_2_5_25_1","volume-title":"Small cholinergic neurons in the caudal sublenticular region\/anterior amygdaloid area in the rat. 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