{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:58:19Z","timestamp":1791298699096,"version":"4.1.0"},"reference-count":41,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2007,9,12]],"date-time":"2007-09-12T00:00:00Z","timestamp":1189555200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2007,11,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Although the main nodes of the neuronal network that regulate paradoxical sleep (PS), also called rapid eye movement sleep, have been identified in rodents, it still needs to be more thoroughly described. We have recently shown that 58% of a hypothalamic neuronal population, the melanin\u2010concentrating hormone (MCH) neurons, are activated after a PS hypersomnia and that MCH, when injected intracerebroventricularly, induces a dose\u2010dependent increase in PS. This suggests that MCH plays a role in PS regulation. Two subpopulations of MCH neurons have been distinguished neurochemically, one that coexpresses cocaine and amphetamine\u2010regulated transcript (CART) and sends ascending projections to the septum and the hippocampus, the other, the non\u2010CART MCH neurons, send descending projections to the lower brainstem and the spinal cord. In order to better characterize the PS\u2010activated MCH neurons it is interesting to determine whether they belong to the first, the second, or both subgroups. We therefore undertook an MCH, CART, and Fos triple immunolabeling study in PS hypersomniac rats. We showed that the MCH neurons activated during PS are part of both subpopulations since we found CART and non\u2010CART MCH\u2010activated neurons. Based on these results and the literature, we propose that MCH could be involved in memory processes and in the inhibition of muscle tone during PS. J. Comp. Neurol. 505:147\u2013157, 2007. \u00a9 2007 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.21482","type":"journal-article","created":{"date-parts":[[2007,9,12]],"date-time":"2007-09-12T21:16:23Z","timestamp":1189631783000},"page":"147-157","source":"Crossref","is-referenced-by-count":88,"title":["Characterization of the melanin\u2010concentrating hormone neurons activated during paradoxical sleep hypersomnia in rats"],"prefix":"10.1002","volume":"505","author":[{"given":"Lucie","family":"Hanriot","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nutabi","family":"Camargo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne 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