{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:02:12Z","timestamp":1791219732692,"version":"4.1.0"},"reference-count":114,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2015,4,2]],"date-time":"2015-04-02T00:00:00Z","timestamp":1427932800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>Current limitations in technology have prevented an extensive analysis of the connections among neurons, particularly within nonmammalian organisms. We developed a transsynaptic viral tracer originally for use in mice, and then tested its utility in a broader range of organisms. By engineering the vesicular stomatitis virus (VSV) to encode a fluorophore and either the rabies virus glycoprotein (RABV\u2010G) or its own glycoprotein (VSV\u2010G), we created viruses that can transsynaptically label neuronal circuits in either the retrograde or anterograde direction, respectively. The vectors were investigated for their utility as polysynaptic tracers of chicken and zebrafish visual pathways. They showed patterns of connectivity consistent with previously characterized visual system connections, and revealed several potentially novel connections. Further, these vectors were shown to infect neurons in several other vertebrates, including Old and New World monkeys, seahorses, axolotls, and <jats:italic>Xenopus<\/jats:italic>. They were also shown to infect two invertebrates, <jats:italic>Drosophila melanogaster<\/jats:italic>, and the box jellyfish, <jats:italic>Tripedalia cystophora<\/jats:italic>, a species previously intractable for gene transfer, although no clear evidence of transsynaptic spread was observed in these species. These vectors provide a starting point for transsynaptic tracing in most vertebrates, and are also excellent candidates for gene transfer in organisms that have been refractory to other methods. J. Comp. Neurol. 523:1639\u20131663, 2015. \u00a9 2015 Wiley Periodicals, Inc.<\/jats:p>","DOI":"10.1002\/cne.23761","type":"journal-article","created":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T07:03:15Z","timestamp":1424156595000},"page":"1639-1663","source":"Crossref","is-referenced-by-count":63,"title":["Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms"],"prefix":"10.1002","volume":"523","author":[{"given":"Nathan A.","family":"Mundell","sequence":"first","affiliation":[{"name":"Department of Genetics Harvard Medical School Boston Massachusetts 02115"},{"name":"Department of Ophthalmology, Howard Hughes Medical Institute Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin T.","family":"Beier","sequence":"additional","affiliation":[{"name":"Department of Genetics Harvard Medical School Boston Massachusetts 02115"},{"name":"Department of Ophthalmology, Howard Hughes Medical Institute Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y. Albert","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Biology and Center for Brain Science Harvard University Cambridge Massachusetts 01238"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sylvain W.","family":"Lapan","sequence":"additional","affiliation":[{"name":"Department of Genetics Harvard Medical School Boston Massachusetts 02115"},{"name":"Department of Ophthalmology, Howard Hughes Medical Institute Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didem","family":"G\u00f6z Ayt\u00fcrk","sequence":"additional","affiliation":[{"name":"Department of Genetics Harvard Medical School Boston Massachusetts 02115"},{"name":"Department of Ophthalmology, Howard Hughes Medical Institute Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir K.","family":"Berezovskii","sequence":"additional","affiliation":[{"name":"Department of Neurobiology Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail R.","family":"Wark","sequence":"additional","affiliation":[{"name":"Department of Genetics Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugene","family":"Drokhlyansky","sequence":"additional","affiliation":[{"name":"Department of Genetics Harvard Medical School Boston Massachusetts 02115"},{"name":"Department of Ophthalmology, Howard Hughes Medical Institute Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Bielecki","sequence":"additional","affiliation":[{"name":"Department of Ecology, Evolution and Marine Biology University of California, Santa Barbara Santa Barbara California 93106"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard T.","family":"Born","sequence":"additional","affiliation":[{"name":"Department of Neurobiology Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander F.","family":"Schier","sequence":"additional","affiliation":[{"name":"Department of Molecular and Cellular Biology and Center for Brain Science Harvard University Cambridge Massachusetts 01238"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constance L.","family":"Cepko","sequence":"additional","affiliation":[{"name":"Department of Genetics Harvard Medical School Boston Massachusetts 02115"},{"name":"Department of Ophthalmology, Howard Hughes Medical Institute Harvard Medical School Boston Massachusetts 02115"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,4,2]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(95)80020-3"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/boc.201200054"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-11-540641"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(93)91606-S"},{"key":"e_1_2_9_6_1","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1099\/00222615-10-1-139","article-title":"Experimental infection of monkeys with Herpesvirus suis (Aujeszky's\u2010disease virus)","volume":"10","author":"Baskerville A","year":"1977","journal-title":"J Med Microbiol"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903350407"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1110854108"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0245-12.2013"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2013.00011"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2008.0213"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn1525"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1081\/CBI-120023343"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901890404"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903460410"},{"key":"e_1_2_9_16_1","first-page":"223","article-title":"[Study of the CO 2 sensitivity symptom induced by vesicular stomatitis virus in Drosophila melanogaster. I. VSV of the New Jersey serotype and the cocal virus]","volume":"121","author":"Bussereau F","year":"1971","journal-title":"Ann Inst Pasteur (Paris)"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/0471733849"},{"key":"e_1_2_9_18_1","first-page":"196","volume-title":"Histologie du Systeme Nerveux de l'homme et des Vertebre's","author":"Cajal SR","year":"1911"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2009.03.007"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1110656"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03441-13"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1990.42.483"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000123821"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(75)90463-1"},{"key":"e_1_2_9_25_1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0014-4886(65)90124-X","article-title":"Development of the retinotectal topographic projection in the chick embryo","volume":"13","author":"Long GR","year":"1965","journal-title":"Exp Neurol"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1056602"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6171033"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3527(08)60787-3"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.05.001"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1095-6433(00)00333-0"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1214441110"},{"issue":"6","key":"e_1_2_9_32_1","doi-asserted-by":"crossref","first-page":"1339","DOI":"10.1099\/0022-1317-75-6-1339","article-title":"Protective efficacy in mice of post\u2010exposure vaccination with vaccinia virus recombinant expressing either rabies virus glycoprotein or nucleoprotein","volume":"75","author":"Fujii H","year":"1994","journal-title":"J Gen Virol"},{"issue":"20","key":"e_1_2_9_33_1","doi-asserted-by":"crossref","first-page":"3616","DOI":"10.1242\/jeb.004044","article-title":"Visually guided obstacle avoidance in the box jellyfish Tripedalia cystophora and Chiropsella bronzie","volume":"210","author":"Garm A","year":"2007","journal-title":"J Exp Biol"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2011.03.054"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2008.09.082"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-36-1-59"},{"key":"e_1_2_9_37_1","first-page":"115","volume-title":"Vision, brain, and behavior in birds","author":"G\u00fcnt\u00fcrk\u00fcn O","year":"1993"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.21339"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.1998.9290"},{"issue":"3","key":"e_1_2_9_40_1","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1113\/jphysiol.2005.099531","article-title":"Olfactoretinal centrifugal input modulates zebrafish retinal ganglion cell activity: a possible role for dopamine\u2010mediated Ca2+ signalling pathways","volume":"569","author":"Huang L","year":"2005","journal-title":"J Physiol"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901700203"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.58.4.415"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.63.3.449"},{"key":"e_1_2_9_44_1","doi-asserted-by":"crossref","first-page":"244","DOI":"10.4269\/ajtmh.1966.15.244","article-title":"Clinical and serological response to laboratory\u2010acquired human infection by Indiana type vesicular stomatitis virus (VSV)","volume":"15","author":"Johnson KM","year":"1966","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0270(00)00296-X"},{"key":"e_1_2_9_46_1","volume-title":"Fields virology","author":"Knipe DM","year":"2007"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1080\/13550280590900427"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(71)90053-9"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523811000149"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2010.11.025"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-05-01883.2000"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2004.03.003"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523809090063"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.12.002"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19980706)396:3<399::AID-CNE9>3.0.CO;2-Y"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00308715"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.64.4.709-724.2000"},{"issue":"13","key":"e_1_2_9_58_1","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1242\/jeb.00397","article-title":"Olfactory input increases visual sensitivity in zebrafish: a possible function for the terminal nerve and dopaminergic interplexiform cells","volume":"206","author":"Maaswinkel H","year":"2003","journal-title":"J Exp Biol"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(62)90290-8"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-98-24111"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3527(08)60583-7"},{"key":"e_1_2_9_62_1","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1093\/jmedent\/36.4.410","article-title":"Bite transmission of vesicular stomatitis virus (New Jersey serotype) to laboratory mice by Simulium vittatum (Diptera: Simuliidae)","volume":"36","author":"Mead DG","year":"1999","journal-title":"J Med Entomol"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5452.485"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1603\/0022-2585-41.1.78"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.110.2.491"},{"key":"e_1_2_9_66_1","first-page":"173","volume-title":"Vision, brain, and behavior in birds","author":"Mey J","year":"1993"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(93)91723-6"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523807070320"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00213215"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt0102-87"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7007-8-126"},{"key":"e_1_2_9_72_1","first-page":"1547","volume-title":"Encyclopedia of virology","author":"Nichol ST","year":"1994"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature03484"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.076588"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2005.11.008"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresrev.2006.08.004"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(96)01151-1"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2011.00001"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.07.080"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2013.08.047"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1999.9556"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(84)90083-6"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0883-07.2007"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0507123102"},{"issue":"2","key":"e_1_2_9_85_1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1046\/j.0021-8782.2001.00012.x","article-title":"The ramification and connections of retinal fibres in layer 7 of the domestic chick optic tectum: a Golgi impregnation, anterograde tracer and GABA\u2010immunogold study","volume":"200","author":"Sebesteny T","year":"2002","journal-title":"J Anat"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2009.02.009"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.10472"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8284675"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1987.tb36288.x"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.64.10.4672-4677.1990"},{"key":"e_1_2_9_91_1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.4269\/ajtmh.1977.26.299","article-title":"Isfahan virus, a new vesiculovirus infecting humans, gerbils, and sandflies in Iran","volume":"26","author":"Tesh R","year":"1977","journal-title":"Am J Trop Med Hyg"},{"key":"e_1_2_9_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902610114"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.17.2.299"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(87)90800-6"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.2536188"},{"key":"e_1_2_9_96_1","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1128\/JVI.76.3.1309-1327.2002","article-title":"Relative neurotropism of a recombinant rhabdovirus expressing a green fluorescent envelope glycoprotein","volume":"76","author":"Pol AN","year":"2002","journal-title":"J Virol"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22131"},{"key":"e_1_2_9_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(89)90003-5"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0361-9230(99)00229-4"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2007.04.058"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22364"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.11007"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0173(80)90011-9"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2007.01.033"},{"key":"e_1_2_9_105_1","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1038\/ncomms3332","article-title":"Axonal and subcellular labeling using modified rabies viral vectors","volume":"4","author":"Wickersham IR","year":"2013","journal-title":"Nat Commun"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(90)90591-V"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903050310"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(20000131)417:1<115::AID-CNE9>3.0.CO;2-B"},{"key":"e_1_2_9_109_1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1128\/jvi.33.1.411-422.1980","article-title":"Vesicular stomatitis virus growth in Drosophila melanogaster cells: G protein deficiency","volume":"33","author":"Wyers F","year":"1980","journal-title":"J Virol"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19970811)384:4<517::AID-CNE3>3.0.CO;2-5"},{"key":"e_1_2_9_111_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.48.32353"},{"key":"e_1_2_9_112_1","first-page":"1201","article-title":"Studies on SV40 in tissue culture \u2014 preliminary step for cancer research \u201cin vitro.\u201d","volume":"21","author":"Yasumura Y","year":"1963","journal-title":"Nihon Rinsho"},{"key":"e_1_2_9_113_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.68.11.7386-7396.1994"},{"key":"e_1_2_9_114_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.22.12236-12242.2004"},{"key":"e_1_2_9_115_1","doi-asserted-by":"publisher","DOI":"10.1038\/330166a0"}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.23761","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.23761","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cne.23761","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.23761","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,6]],"date-time":"2023-10-06T14:31:47Z","timestamp":1696602707000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.23761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4,2]]},"references-count":114,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["10.1002\/cne.23761"],"URL":"https:\/\/doi.org\/10.1002\/cne.23761","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,4,2]]}}}