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Compared to the striped cortical compartmentalization which are labeled by molecular markers, such as aldolase C (Aldoc) or zebrin II, the presumed corresponding organization of the cerebellar nuclei and inferior olivary nucleus has not been much clarified. We focused on the expression pattern of <jats:italic>pcdh10<\/jats:italic> gene coding cell adhesion molecule protocadherin 10 (Pcdh10) in adult mice. In the cortex, <jats:italic>pcdh10<\/jats:italic> was strongly expressed in (a) Aldoc\u2010positive vermal stripes a+\/\/2+ in lobules VI\u2013VII, (b) paravermal narrow stripes c+, d+, 4b+, 5a+ in crus I and neighboring lobules, and (c) paravermal stripes 4+\/\/5+ across all lobules from lobule III to paraflocculus. In the cerebellar nuclei, <jats:italic>pcdh10<\/jats:italic> was expressed strongly in the caudal part of the medial nucleus and the lateral part of the posterior interposed nucleus which project less to the medulla or to the red nucleus than to other metencephalic, mesencephalic, and diencephalic areas. In the inferior olive, <jats:italic>pcdh10<\/jats:italic> was expressed strongly in the rostral and medioventrocaudal parts of the medial accessory olive which has connection with the mesencephalic areas rather than the spinal cord. Olivocerebellar and corticonuclear axonal labeling confirmed that the three cortical <jats:italic>pcdh10<\/jats:italic>\u2010positive areas were topographically connected to the nuclear and olivary <jats:italic>pcdh10<\/jats:italic>\u2010positive areas, demonstrating their coincidence with modular structures in the olivo\u2010cortico\u2010nuclear loop. We speculate that some of these modules are functionally involved in various nonsomatosensorimotor tasks via their afferent and efferent connections.<\/jats:p>","DOI":"10.1002\/cne.24499","type":"journal-article","created":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T16:03:57Z","timestamp":1531497837000},"page":"2406-2427","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Cerebellar modules in the olivo\u2010cortico\u2010nuclear loop demarcated by <i>pcdh10<\/i> expression in the adult mouse"],"prefix":"10.1002","volume":"526","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1397-0669","authenticated-orcid":false,"given":"Gideon A.","family":"Sarpong","sequence":"first","affiliation":[{"name":"Department of Systems Neurophysiology Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University  Tokyo 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