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In mice, two subdivisions of the dorsal lateral geniculate nucleus (dLGN), the core and the shell, organize distinct parallel channels to transmit visual information from the retina to the primary visual cortex (V1). To investigate how the dLGN core and shell differentially integrate visual information and other modalities, we mapped synaptic input sources to each dLGN subdivision at the cell\u2010type level with G\u2010deleted rabies viral vectors. The monosynaptic circuit tracing revealed that dLGN core neurons received inputs from alpha\u2010RGCs, Layer 6 neurons of the V1, the superficial and intermediate layers of the superior colliculus (SC), the internal ventral LGN, the lower layer of the external ventral LGN (vLGNe), the intergeniculate leaf, the thalamic reticular nucleus (TRN), and the pretectal nucleus (PT). Conversely, shell neurons received inputs from alpha\u2010RGCs and direction\u2010selective ganglion cells of the retina, Layer 6 neurons of the V1, the superficial layer of the SC, the superficial and lower layers of the vLGNe, the TRN, the PT, and the parabigeminal nucleus. The present study provides anatomical evidence of the cell type\u2010 and layer\u2010specific convergence in dLGN core and shell neurons. These findings suggest that dLGN core neurons integrate and process more multimodal information along with visual information than shell neurons and that LGN core and shell neurons integrate different types of information, send their own convergent information to discrete populations of the V1, and differentially contribute to visual perception and behavior.<\/jats:p>","DOI":"10.1002\/cne.25075","type":"journal-article","created":{"date-parts":[[2020,11,25]],"date-time":"2020-11-25T06:34:33Z","timestamp":1606286073000},"page":"2099-2124","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Cell type\u2010 and layer\u2010specific convergence in core and shell neurons of the dorsal lateral geniculate nucleus"],"prefix":"10.1002","volume":"529","author":[{"given":"Sayumi","family":"Okigawa","sequence":"first","affiliation":[{"name":"Laboratory of Cellular Pharmacology, Graduate School of Pharmaceutical Sciences Nagoya 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