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To better understand the pathogenesis of these diseases, it is important to determine the expression patterns of the different Na\n                    <jats:sup>+<\/jats:sup>\n                    \/K\n                    <jats:sup>+<\/jats:sup>\n                    \u2010ATPase subunits within the brain and among specific cell types. Using two available scRNA\u2010Seq databases from the adult mouse nervous system, we examined the mRNA expression patterns of the different isoforms of the Na\n                    <jats:sup>+<\/jats:sup>\n                    \/K\n                    <jats:sup>+<\/jats:sup>\n                    \u2010ATPase \u03b1, \u03b2 and\n                    <jats:italic>Fxyd<\/jats:italic>\n                    subunits at the single\u2010cell level among brain regions and various neuronal populations. We subsequently identified specific types of neurons enriched with transcripts for \u03b11 and \u03b13 isoforms and elaborated how \u03b13\u2010expressing neuronal populations govern cerebellar neuronal circuits. We further analyzed the co\u2010expression network for \u03b11 and \u03b13 isoforms, highlighting the genes that positively correlated with \u03b11 and \u03b13 expression. The top 10 genes for \u03b11 were\n                    <jats:italic>Chn2<\/jats:italic>\n                    ,\n                    <jats:italic>Hpcal1<\/jats:italic>\n                    ,\n                    <jats:italic>Nrgn<\/jats:italic>\n                    ,\n                    <jats:italic>Neurod1<\/jats:italic>\n                    ,\n                    <jats:italic>Selm<\/jats:italic>\n                    ,\n                    <jats:italic>Kcnc1<\/jats:italic>\n                    ,\n                    <jats:italic>Snrk<\/jats:italic>\n                    ,\n                    <jats:italic>Snap25<\/jats:italic>\n                    ,\n                    <jats:italic>Ckb<\/jats:italic>\n                    and\n                    <jats:italic>Ccndbp1<\/jats:italic>\n                    and for \u03b13 were\n                    <jats:italic>Sorcs3<\/jats:italic>\n                    ,\n                    <jats:italic>Eml5<\/jats:italic>\n                    ,\n                    <jats:italic>Neurod2<\/jats:italic>\n                    ,\n                    <jats:italic>Ckb<\/jats:italic>\n                    ,\n                    <jats:italic>Tbc1d4<\/jats:italic>\n                    ,\n                    <jats:italic>Ptprz1<\/jats:italic>\n                    ,\n                    <jats:italic>Pvrl1<\/jats:italic>\n                    ,\n                    <jats:italic>Kirrel3<\/jats:italic>\n                    ,\n                    <jats:italic>Pvalb<\/jats:italic>\n                    , and\n                    <jats:italic>Asic2<\/jats:italic>\n                    .\n                  <\/jats:p>","DOI":"10.1002\/cne.25234","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T05:46:50Z","timestamp":1629438410000},"page":"627-647","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Comparative description of the\n                    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