{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T00:28:01Z","timestamp":1787963281489,"version":"build-2784847793"},"reference-count":128,"publisher":"Wiley","issue":"15","license":[{"start":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T00:00:00Z","timestamp":1655251200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["DFG FE789\/8\u20101"],"award-info":[{"award-number":["DFG FE789\/8\u20101"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The structure of the mammalian auditory brainstem is evolutionarily highly plastic, and distinct nuclei arrange in a species\u2010dependent manner. Such anatomical variability is present in the superior olivary complex (SOC) and the nuclei of the lateral lemniscus (LL). Due to the structure\u2013function relationship in the auditory brainstem, the identification of individual nuclei supports the understanding of sound processing. Here, we comparatively describe the nucleus arrangement and the expression of functional markers in the auditory brainstem of the two bat species\n                    <jats:italic>Phyllostomus discolor<\/jats:italic>\n                    and\n                    <jats:italic>Carollia perspicillata<\/jats:italic>\n                    . Using immunofluorescent labeling, we describe the arrangement and identity of the SOC and LL nuclei based on the expression of synaptic markers (vesicular glutamate transporter 1 and glycine transporter 2), calcium\u2010binding proteins, as well as the voltage\u2010gated ion channel subunits Kv1.1 and HCN1. The distribution of excitatory and inhibitory synaptic labeling appears similar between both species and matches with that of other mammals. The detection of calcium\u2010binding proteins indicates species\u2010dependent differences and deviations from other mammals. Kv1.1 and HCN1 show largely the same expression pattern in both species, which diverges from other mammals, indicating functional adaptations in the cellular physiology of bat neurons.\n                  <\/jats:p>","DOI":"10.1002\/cne.25355","type":"journal-article","created":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T08:35:39Z","timestamp":1655282139000},"page":"2762-2781","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Structural arrangement of auditory brainstem nuclei in the bats\n                    <i>Phyllostomus discolor<\/i>\n                    and\n                    <i>Carollia perspicillata<\/i>"],"prefix":"10.1002","volume":"530","author":[{"given":"Christina","family":"P\u00e4tz","sequence":"first","affiliation":[{"name":"Institute of Zoology University of Veterinary Medicine Hannover  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Console\u2010Meyer","sequence":"additional","affiliation":[{"name":"Institute of Zoology University of Veterinary Medicine Hannover  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0957-4241","authenticated-orcid":false,"given":"Felix","family":"Felmy","sequence":"additional","affiliation":[{"name":"Institute of Zoology University of Veterinary Medicine Hannover  Hannover Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,15]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(90)90109-3"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00585.2011"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/7493286"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903340207"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3161\/001.006.0103"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-015-1181-x"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7580.2005.00491.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-004-1054-8"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(90)91025-C"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1968.31.3.442"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/417543a"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnsyn.2020.560008"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1121\/1.3519396"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2000.00143.x"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00185994"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903280305"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1055-20.2020"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2015.00074"},{"key":"e_1_2_10_20_1","first-page":"1","article-title":"Carollia perspicillata","volume":"417","author":"Cloutier D.","year":"1992","journal-title":"Mammalian Species"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1760-10.2010"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.a.20254"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.11-11-03456.1991"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-16-06953.2002"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00225826"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00225827"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2450-11.2011"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01041.2012"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2004.03604.x"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00523.2016"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1994.sp020303"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.62183"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3948"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2016.00069"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1545-19.2020"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1996.76.2.1121"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1959.197.3.527"},{"key":"e_1_2_10_38_1","first-page":"14","article-title":"Fronto\u2010temporal coupling dynamics during spontaneous activity and auditory processing in the bat Carollia perspicillata","volume":"14","author":"Garcia\u2010Rosales F.","year":"2020","journal-title":"Frontiers in Neural Circuits"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1590\/1519-6984.210489"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00092.2005"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1159\/000006530"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1969.32.4.613"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0600-17.2017"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5955(99)00187-2"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1994.71.2.706"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0029(20001115)51:4<382::AID-JEMT7>3.0.CO;2-7"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2014.00116"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903430412"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10914-005-6945-2"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btl505"},{"key":"e_1_2_10_51_1","first-page":"201","volume-title":"Archiv f\u00fcr Anatomie und Physiologie","author":"Held H.","year":"1893"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(89)90644-6"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902940307"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.2307\/3503910"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-008-0201-5"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-9-65"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22521"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.1059"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.24529"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-0102(86)90002-7"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2011.02.050"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1995.73.3.1043"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn810"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.21929"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3882-11.2012"},{"key":"e_1_2_10_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5955(03)00025-X"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0953-816X.2004.03456.x"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00375.2003"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2014.282194"},{"key":"e_1_2_10_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.06.028"},{"key":"e_1_2_10_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2006.12.006"},{"key":"e_1_2_10_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2013.11.035"},{"key":"e_1_2_10_73_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00613.2006"},{"key":"e_1_2_10_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msx116"},{"key":"e_1_2_10_75_1","doi-asserted-by":"publisher","DOI":"10.2307\/3504258"},{"key":"e_1_2_10_76_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903140405"},{"key":"e_1_2_10_77_1","doi-asserted-by":"publisher","DOI":"10.1644\/801.1"},{"key":"e_1_2_10_78_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.114702"},{"key":"e_1_2_10_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960325)367:1<90::AID-CNE7>3.0.CO;2-E"},{"key":"e_1_2_10_80_1","first-page":"622","article-title":"Echolocation calls and neurophysiological correlations with auditory response properties in the inferior colliculus of Pipistrellus abramus (Microchiroptera: Vespertilionidae)","volume":"46","author":"Luo F.","year":"2007","journal-title":"Zoological Studies"},{"key":"e_1_2_10_81_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03193235"},{"key":"e_1_2_10_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(93)90020-2"},{"key":"e_1_2_10_83_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2530"},{"key":"e_1_2_10_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(90)90424-A"},{"key":"e_1_2_10_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.24290"},{"key":"e_1_2_10_86_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.03-01-00237.1983"},{"key":"e_1_2_10_87_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.23232"},{"key":"e_1_2_10_88_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4790"},{"key":"e_1_2_10_89_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.50.1.121"},{"key":"e_1_2_10_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2016.02.003"},{"key":"e_1_2_10_91_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1660-08.2008"},{"key":"e_1_2_10_92_1","doi-asserted-by":"publisher","DOI":"10.1007\/s101620010057"},{"key":"e_1_2_10_93_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp184"},{"key":"e_1_2_10_94_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-020-02138-y"},{"key":"e_1_2_10_95_1","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0106-19.2019"},{"key":"e_1_2_10_96_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22166"},{"key":"e_1_2_10_97_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00971.2011"},{"key":"e_1_2_10_98_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.10713"},{"key":"e_1_2_10_99_1","first-page":"17","article-title":"Die ontogenetische Entwicklung der Vokalisation bei Phyllostomus discolor (Chiroptera)","volume":"50","author":"Rother G.","year":"1985","journal-title":"Zeitschrift f\u00fcr S\u00e4ugetierkunde"},{"key":"e_1_2_10_100_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00125.2002"},{"key":"e_1_2_10_101_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19971215)389:2<264::AID-CNE6>3.0.CO;2-#"},{"key":"e_1_2_10_102_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-7156-1"},{"key":"e_1_2_10_103_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2019"},{"key":"e_1_2_10_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"e_1_2_10_105_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19970317)379:3<363::AID-CNE4>3.0.CO;2-1"},{"key":"e_1_2_10_106_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902010104"},{"key":"e_1_2_10_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00229781"},{"key":"e_1_2_10_108_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902380302"},{"key":"e_1_2_10_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960422)368:1<100::AID-CNE7>3.0.CO;2-7"},{"key":"e_1_2_10_110_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.900980303"},{"key":"e_1_2_10_111_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00717.2003"},{"key":"e_1_2_10_112_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002650050454"},{"key":"e_1_2_10_113_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903580202"},{"key":"e_1_2_10_114_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903410409"},{"key":"e_1_2_10_115_1","doi-asserted-by":"publisher","DOI":"10.1007\/s004410050869"},{"key":"e_1_2_10_116_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902920305"},{"key":"e_1_2_10_117_1","doi-asserted-by":"publisher","DOI":"10.2307\/1379850"},{"key":"e_1_2_10_118_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1999.81.6.2862"},{"key":"e_1_2_10_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00359-016-1121-0"},{"key":"e_1_2_10_120_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.22428"},{"key":"e_1_2_10_121_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1994.71.6.2014"},{"key":"e_1_2_10_122_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1994.71.6.1999"},{"key":"e_1_2_10_123_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2014.00065"},{"key":"e_1_2_10_124_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1990.64.2.465"},{"key":"e_1_2_10_125_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903130102"},{"key":"e_1_2_10_126_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01215.2005"},{"key":"e_1_2_10_127_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.18-18-07200.1998"},{"key":"e_1_2_10_128_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902070102"},{"key":"e_1_2_10_129_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902070103"}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.25355","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/cne.25355","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.25355","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T09:23:39Z","timestamp":1692696219000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.25355"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,15]]},"references-count":128,"journal-issue":{"issue":"15","published-print":{"date-parts":[[2022,10]]}},"alternative-id":["10.1002\/cne.25355"],"URL":"https:\/\/doi.org\/10.1002\/cne.25355","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1002\/CNE.25355\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/CNE.25355\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/CNE.25355\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/CNE.25355\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/CNE.25355\/v3\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/CNE.25355\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/CNE.25355\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/CNE.25355\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1002\/CNE.25355\/v1\/review1","asserted-by":"object"}]},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,15]]},"assertion":[{"value":"2021-10-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}