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Following physiological characterizations, the recorded single cells were labeled for morphological identification. It was found that the zebrafish Purkinje cells are surprisingly diverse. Based on their physiology and morphology, they can be classified into at least three subtypes: Type I, a\n                    <jats:italic>narrow spike cell<\/jats:italic>\n                    , which fires only narrow Na\n                    <jats:sup>+<\/jats:sup>\n                    spikes (&lt;3\u00a0ms in duration), and has a single primary dendrite with an arbor restricted to the distal molecular layer; Type II, a\n                    <jats:italic>broad spike cell<\/jats:italic>\n                    , which fires broad Ca\n                    <jats:sup>2+<\/jats:sup>\n                    spikes (5\u20137\u00a0ms in duration) and has a primary dendrite with limited branching in the inner molecular layer and then further radiates throughout the molecular layer; and Type III, a\n                    <jats:italic>very broad spike cell<\/jats:italic>\n                    , which fires very broad Ca\n                    <jats:sup>2+<\/jats:sup>\n                    spikes (\u226510\u00a0ms in duration) and has a dense proximal dendritic arbor that is either restricted to the inner molecular layer (Type IIIa), or radiates throughout the entire molecular layer (Type IIIb). The graded paired\u2010pulse facilitation of these Purkinje cells\u2019 responses to parallel fiber activations and the all\u2010or\u2010none, paired\u2010pulse depression of climbing fiber activation are largely similar to those reported for mammals. The labeled axon terminals of these Purkinje cells end locally, as reported for larval zebrafish. The present study provides evidence that the corresponding functional circuitry and information processing differ from what has been well\u2010established in the mammalian cerebellum.\n                  <\/jats:p>","DOI":"10.1002\/cne.25435","type":"journal-article","created":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T07:45:21Z","timestamp":1669880721000},"page":"461-485","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Diversity of cellular physiology and morphology of Purkinje cells in the adult zebrafish cerebellum"],"prefix":"10.1002","volume":"531","author":[{"given":"Gerhard","family":"Magnus","sequence":"first","affiliation":[{"name":"Department of Biology University of Washington  Seattle Washington USA"},{"name":"Center for Integrative Brain Research Seattle Children's Research Institute  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junling","family":"Xing","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Neuroscience Xijing Hospital  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Center for Integrative Brain Research Seattle Children's Research Institute  Seattle Washington USA"},{"name":"Department of Pediatrics and Neuroscience Xijing Hospital  Xi'an China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2298-4859","authenticated-orcid":false,"given":"Victor Z.","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Biology University of Washington  Seattle Washington USA"},{"name":"Center for Integrative Brain Research Seattle Children's Research Institute  Seattle Washington USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11057"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2434"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.6565-10.2011"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00016.2014"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2001.85.1.323"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.21974"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2009.04.013"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1992.68.3.843"},{"key":"e_1_2_9_10_1","first-page":"375","volume-title":"Electroreception","author":"Bell C. 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