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The results revealed long glial processes interconnecting the AP with deeper areas of brain stem. The laminin and \u03b2\u2010dystroglycan immunolabeling altered along the vessels indicating alterations of the gliovascular relations. These and the distributions of glial markers displayed similarities to the SFO and OVLT. In every organ, there was a central area with vimentin\u2010 and nestin\u2010immunopositive glia, whereas GFAP and the water\u2010channel aquaporin 4 were found at the periphery. This separation supports different functions of the two regions. The presence of nestin may indicate stem cell capabilities, whereas aquaporin 4 has been suggested by other studies to be a possible participant of osmoperception. Numerous S100\u2010immunopositive glial cells were found approximately evenly distributed in both parts of the AP. Frequency of glutamine synthetase\u2010immunoreactive cells was similar in the surrounding brain tissue in contrast to that found in the OVLT and SFO. Our findings on the three sensory circumventricular organs (AP, OVLT, and SFO) are compared in parallel.<\/jats:p>","DOI":"10.1002\/cne.25470","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T08:01:38Z","timestamp":1680163298000},"page":"866-887","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Three\u2010plane description of astroglial architecture and gliovascular connections of area postrema in rat: Long tanycyte connections to other parts of brainstem"],"prefix":"10.1002","volume":"531","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1621-2118","authenticated-orcid":false,"given":"Mih\u00e1ly","family":"K\u00e1lm\u00e1n","sequence":"first","affiliation":[{"name":"Department of Anatomy, Histology and Embryology Semmelweis University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erzs\u00e9bet","family":"Oszwald","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Histology and Embryology Semmelweis University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0402-0917","authenticated-orcid":false,"given":"K\u00e1roly","family":"P\u00f3csai","sequence":"additional","affiliation":[{"name":"Department of Anatomy, Histology and Embryology Semmelweis University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20794"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001090050215"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2004.08.049"},{"key":"e_1_2_11_5_1","first-page":"1","article-title":"Distribution of components of basal lamina and dystrophin\u2010dystroglycan complex in the rat pineal gland: Differences from the brain tissue and between the subdivisions of the gland","volume":"25","author":"Bagyura Zs.","year":"2010","journal-title":"Histology and Histopathology"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0361\u20109230(92)90143\u2010L"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2004.08.047"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1012867108"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2009.04.007"},{"key":"e_1_2_11_10_1","first-page":"3853","article-title":"Distribution of the glutamate transporters GLAST and GLT\u20101 in rat circumventricular organs, meninges, and dorsal root ganglia","volume":"421","author":"Berger U. 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