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The cortical modules or zones are organized into longitudinal zebrin stripes which are extended across transverse cerebellar lobules. However, how cerebellar lobules, which are related to the cerebellar functional localization, are incorporated into the olivo\u2010cortico\u2010nuclear topographic organization has not been fully clarified. In the present study, we analyzed the lobular topography in the CN and IO by making 57 small bidirectional tracer injections in the lateral zebrin\u2010positive stripes equivalent with C2, D1, and D2 zones in every hemispheric lobule in zebrin stripe\u2010visualized mice.<\/jats:p><jats:p>C2, D1, and D2 zones were connected to the lateral part of the posterior interpositus nucleus (lPIN), and caudal and rostral parts of the lateral nucleus (cLN, rLN), respectively, and from the rostral part of the medial accessory olive (rMAO), and ventral and dorsal lamellas of the PO (vPO, dPO), respectively, as reported. Within these areas, crus I was specifically connected to the ventral parts of the lPIN, cLN, and rLN, and from the rostrolateral part of the rMAO and the lateral parts of the vPO and dPO.<\/jats:p><jats:p>The results indicated that the cerebellar modules have lobule\u2010related subdivisions and that crus I is topographically distinct from other lobules. We speculate that crus I and crus I\u2010connected subdivisions in the CN and IO are involved more in nonmotor functions than other neighboring areas in the mouse.<\/jats:p>","DOI":"10.1002\/cne.25527","type":"journal-article","created":{"date-parts":[[2023,8,16]],"date-time":"2023-08-16T17:01:42Z","timestamp":1692205302000},"page":"1633-1650","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Topographic organization in the cerebellar nuclei and inferior olive in relation to cerebellar hemispheric lobules in the mouse: Distinction between crus I and neighboring lobules"],"prefix":"10.1002","volume":"531","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2911-6181","authenticated-orcid":false,"given":"Richard Nana Abankwah","family":"Owusu\u2010Mensah","sequence":"first","affiliation":[{"name":"Department of Systems Neurophysiology, Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University 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