{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:43:07Z","timestamp":1787506987876,"version":"build-2736575974"},"reference-count":58,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T00:00:00Z","timestamp":1706486400000},"content-version":"vor","delay-in-days":28,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002241","name":"Japan Science and Technology Agency","doi-asserted-by":"publisher","award":["JPMJSP2120"],"award-info":[{"award-number":["JPMJSP2120"]}],"id":[{"id":"10.13039\/501100002241","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["KAKENHI 19K06919"],"award-info":[{"award-number":["KAKENHI 19K06919"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["KAKENHI 21F21107"],"award-info":[{"award-number":["KAKENHI 21F21107"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    The cerebellar projection from the trigeminal nuclear complex is one of the major populations of the cerebellar inputs. Although this projection is essential in cerebellar functional processing and organization, its morphological organization has not been systematically clarified. The present study addressed this issue by lobule\u2010specific retrograde neuronal labeling and single axonal reconstruction with anterograde labeling. The cerebellar projection arose mainly from the interpolaris subdivision of the spinal trigeminal nucleus (Sp5I) and the principal trigeminal sensory nucleus (Pr5). Although crus II, paramedian lobule, lobule IX, and simple lobule were the major targets, paraflocculus, and other lobules received some projections. Reconstructed single trigeminocerebellar axons showed 77.8 mossy fiber terminals on average often in multiple lobules but no nuclear collaterals. More terminals were located in zebrin\u2010negative or lightly\u2010positive compartments than in zebrin\u2010positive compartments. While Pr5 axons predominantly projected to ipsilateral crus II, Sp5I axons projected either predominantly to crus II and paramedian lobule often bilaterally, or predominantly to lobule IX always ipsilaterally. Lobule IX\u2010predominant\u2010type Sp5I neurons specifically expressed\n                    <jats:italic>Gpr26<\/jats:italic>\n                    .\n                    <jats:italic>Gpr26<\/jats:italic>\n                    \u2010tagged neuronal labeling produced a peculiar mossy fiber distribution, which was dense in the dorsolateral lobule IX and extending transversely to the dorsal median apex in lobule IX. The projection to the cerebellar nuclei was observed in collaterals of ascending Sp5I axons that project to the diencephalon. In sum, multiple populations of trigeminocerebellar projections showed divergent projections to cerebellar lobules. The projection was generally complementary with the pontine projection and partly matched with the reported orofacial receptive field arrangement.\n                  <\/jats:p>","DOI":"10.1002\/cne.25581","type":"journal-article","created":{"date-parts":[[2024,1,29]],"date-time":"2024-01-29T06:36:14Z","timestamp":1706510174000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Single axonal characterization of trigeminocerebellar projection patterns in the mouse"],"prefix":"10.1002","volume":"532","author":[{"given":"Tianzhuo","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Systems Neurophysiology Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoyuki","family":"Numata","sequence":"additional","affiliation":[{"name":"Department of Systems Neurophysiology Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Systems Neurophysiology Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuma","family":"Mizuno","sequence":"additional","affiliation":[{"name":"Department of Systems Neurophysiology Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences  Bunkyo\u2010ku Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7099-9209","authenticated-orcid":false,"given":"Nguyen\u2010Minh","family":"Viet","sequence":"additional","affiliation":[{"name":"Department of Systems Neurophysiology Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences  Bunkyo\u2010ku Tokyo Japan"},{"name":"F. 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