{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T18:59:48Z","timestamp":1761764388346},"reference-count":53,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":9248,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1979,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Several genetically distinct color phases of mink, which all show an abnormal reduction of pigment in the retinal pigment epithelium and which also show abnormalities of the retinofugal pathways, have been studied. Autoradiographic methods have been used to demonstrate the retino\u2010geniculate pathways, and retrograde degeneration or the retrograde transport of horseradish peroxidase has been used for the geniculo\u2010cortical pathways.<\/jats:p><jats:p>The retino\u2010geniculate abnormality is mild in some of the color phases and extremely severe in others, but within any one color phase the variability is relatively low. Although the severity of the abnormality varies between color phases, a rather specific pattern of abnormal geniculate innervation is recognizable for mink in general and this is distinct from that found in Siamese cats. In the abnormal mink the size of geniculate lamina A1 is reduced and there is an abnormal crossed input going to the intermediate sectors of this reduced layer. Layer C1 also receives an abnormal crossed input, but this is more variable than that going to A1 and there appears to be little correspondence, retinotopically, between the normal inputs to layers A1 and C1. In some of the abnormal mink there are interruptions within the cytoarchitectonically definable layer A1, and opposite these gaps reduplications of layer A are commonly seen, as though there is an intrinsic geniculate mechanism for generating the characteristic multilaminar geniculate structure. However, there are also numerous examples of fusions between layers receiving afferents from the same eye, and these demonstrate that the development of geniculate lamination must also be under the influence of the retinal inputs.<\/jats:p><jats:p>The geniculo\u2010cortical pathway shows a normal topography in most of the mink. Abnormal geniculo\u2010cortical projections, comparable to the \u201cBoston\u201d pattern of Siamese cats are extremely rare, and their occurrence could not be correlated with the severity of the retino\u2010geniculate abnormality or with the laminar pattern in the lateral geniculate nucleus. We suggest that the development of one or the other pattern of geniculo\u2010cortical projection may depend upon the relative timing of the two mechanisms that produce the geniculate lamination.<\/jats:p>","DOI":"10.1002\/cne.901850404","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T19:48:49Z","timestamp":1104608929000},"page":"623-655","source":"Crossref","is-referenced-by-count":34,"title":["Abnormal retino\u2010geniculate and geniculo\u2010cortical pathways in several genetically distinct color phases of the mink <i>(Mustela vison)<\/i>"],"prefix":"10.1002","volume":"185","author":[{"given":"R. W.","family":"Guillery","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. D.","family":"Oberdorfer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. H.","family":"Murphy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1962.sp006991"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(78)90357-8"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1126\/science.628845","article-title":"Optokinetic eye movements in albino rabbits: inversion in anterior visual field","volume":"199","author":"Collewijn H.","year":"1977","journal-title":"Science"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(72)90344-7"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/231465a0"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0014-4886(72)90002-7","article-title":"Retinogeniculostriate projections in guinea pigs: albino and pigmented strains compared","volume":"37","author":"Creel D. J.","year":"1972","journal-title":"Exp. Neur."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901660406"},{"key":"e_1_2_1_9_1","first-page":"430","article-title":"Asymmetric visually evoked potentials in human albinos: evidence for visual system anomalies","volume":"13","author":"Creel D. J.","year":"1974","journal-title":"Invest. Ophthalmol."},{"key":"e_1_2_1_10_1","volume-title":"Laboratory Technique in Biology and Medicine","author":"Emmel V. M.","year":"1964"},{"key":"e_1_2_1_11_1","first-page":"259","article-title":"The effects of monocular deprivation on different neuronal classes in the lateral geniculate nucleus of the cat","volume":"28","author":"Garey L. J.","year":"1977","journal-title":"Exp. Brain Res."},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/237375a0","article-title":"The visual system and \u201cneuronal specificity\u201d","volume":"273","author":"Gaze R. M.","year":"1972","journal-title":"Nature (London)"},{"key":"e_1_2_1_13_1","unstructured":"Geisert E. E. Jr.1978The Cortical Projections of the Lateral Geniculate Nucleus in the Cat. Ph. D. Thesis. U. Wisconsin Madison."},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/14.4.291"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(69)90213-3"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901380307"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(71)90121-1"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(71)90062-X"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901460306"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901490403"},{"key":"e_1_2_1_21_1","doi-asserted-by":"crossref","unstructured":"Guillery R. W.1979A speculative essay on geniculate lamination and its development.Prog. Brain Res. in press.","DOI":"10.1016\/S0079-6123(08)61317-5"},{"key":"e_1_2_1_22_1","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1101\/SQB.1976.040.01.057","article-title":"Adaptive synaptic connections formed in the visual pathways in response to congenitally abnormal inputs","volume":"40","author":"Guillery R. W.","year":"1975","journal-title":"Cold Spring Harbor Symp. Quant. Biol."},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901740103"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901430106"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.180.4092.1287"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901760404"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901610307"},{"key":"e_1_2_1_28_1","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1152\/jn.1972.35.4.518","article-title":"Relay of receptive\u2010field properties in the dorsal lateral geniculate nucleus of the cat","volume":"35","author":"Hoffman K. P.","year":"1972","journal-title":"J. Neurophysiol."},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901730308"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1971.sp009603"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(73)90253-9"},{"key":"e_1_2_1_32_1","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1002\/cne.901470203","article-title":"Discontinuities in the dorsal lateral geniculate nucleus corresponding to the optic disc: a comparative study","volume":"147","author":"Kaas J. H.","year":"1972","journal-title":"J. Comp. Neur."},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901820304"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901720402"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.149.3691.1506"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901580403"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901790102"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.1977.0040"},{"key":"e_1_2_1_39_1","first-page":"573","article-title":"Effect of prenatal unilateral eye enucleation on the formation of layers and retinal connections in the dorsal lateral geniculate nucleus (LGd) of the rhesus monkey","volume":"3","author":"Rakic P.","year":"1977","journal-title":"Neuroscience Abst."},{"key":"e_1_2_1_40_1","volume-title":"Techniques of Autoradiography","author":"Rogers A. W.","year":"1973"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901530303"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901590103"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901540302"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(74)90219-4"},{"key":"e_1_2_1_45_1","volume-title":"Genetics of the Ranch Mink","author":"Shackelford R. M.","year":"1956"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901710206"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901710207"},{"key":"e_1_2_1_48_1","first-page":"57","article-title":"Rearrangement of geniculocortical and corticocortical connections in Boston Siamese cats","volume":"3","author":"Shatz C. J.","year":"1977","journal-title":"Neuroscience Soc. Abstracts"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(76)91062-3"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901800409"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901800408"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1976.39.6.1193"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(76)90054-6"},{"key":"e_1_2_1_54_1","volume-title":"Heritable Diseases of Amino Acid Metabolism","author":"Witkop C. J.","year":"1973"}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.901850404","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.901850404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,12]],"date-time":"2023-11-12T23:38:02Z","timestamp":1699832282000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.901850404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1979,6,15]]},"references-count":53,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1979,6,15]]}},"alternative-id":["10.1002\/cne.901850404"],"URL":"https:\/\/doi.org\/10.1002\/cne.901850404","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[1979,6,15]]}}}