{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:28:32Z","timestamp":1757543312064},"reference-count":57,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":8439,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1981,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Following a series of lesions in dorsal (DPML) and ventral (VPML) divisions of tree shrew (<jats:italic>Tupaia<\/jats:italic>) paramedian lobule (PML), the distribution of degenerated axons within the deep cerebellar nuclei was determined using the Fink and Heimer ('67) method. Damage to PML produced axonal degeneration in lateral (NL), anterior interposed (NIA), and posterior interposed (NIP) cerebellar nuclei. No degenerated fibers could be traced to either the medial cerebellar nucleus or vestibular complex, via juxtarestiform body, from lesions in PML. Corticonuclear fibers to NL, NIA, and NIP from PML cortex are topographically organized. Subsequent to lesions of lateral DPML, axonal debris is found in rostral and medial NL, while the lateral edge of VPML projects primarily into medial NL. According to the terminology of Voogd ('69) these lateral regions of PML represent the D zone. The NIP receives corticonuclear input from a relatively wide middle area of both portions of PML, interpreted as the C<jats:sub>2<\/jats:sub> zone. There is some evidence which suggests that medial portions of the C<jats:sub>2<\/jats:sub> area of DPML project into more lateral areas of NIP, while lateral regions of this zone in DPML are related to more medial NIP. This projection pattern is inverted for the C<jats:sub>2<\/jats:sub> area of VPML; medial C<jats:sub>2<\/jats:sub> to medial NIP, lateral C<jats:sub>2<\/jats:sub> to lateral NIP. Corticonuclear fibers of PML which enter NIA appear to arise from a narrow, irregular, partially discontinuous strip of cortex located at the interface of the D and C<jats:sub>2<\/jats:sub> areas in lateral PML and from a wider, more regular region in the most medial areas of this lobule. These represent, respectively, the C<jats:sub>3<\/jats:sub> and C<jats:sub>1<\/jats:sub> zones.<\/jats:p><jats:p>Although an overall pattern of zones is present, there is evidence to suggest that their spatial organization differs from DPML to VPML. The zonal pattern appears to be more obvious in VPML, while this pattern for DPML is less distinct. This is interpreted as indicating that either (1) zones C<jats:sub>1<\/jats:sub>\u2212C<jats:sub>3<\/jats:sub> overlap to a greater degree in DPML than in VPML, or (2) zones C<jats:sub>1<\/jats:sub> and C<jats:sub>3<\/jats:sub> may converge in rostral DPML, partially obliterating the intervening zone C<jats:sub>2<\/jats:sub>. The different ways in which zonal terminology is applied to both corticonuclear and certain of the afferent cerebellar systems are discussed.<\/jats:p>","DOI":"10.1002\/cne.902010108","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T16:46:52Z","timestamp":1104598012000},"page":"99-119","source":"Crossref","is-referenced-by-count":22,"title":["Cerebellar corticonuclear fibers of the paramedian lobule of tree shrew (<i>Tupaia glis<\/i>) with comments on zones"],"prefix":"10.1002","volume":"201","author":[{"given":"D. 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