{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T03:54:52Z","timestamp":1773806092544,"version":"3.50.1"},"reference-count":98,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":6569,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1986,10,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The 2\u2010deoxyglucose (2DG) method was used to map functional activity in the auditory system of chicks that had been subjected to unilateral or bilateral cochlea removal. Following survival times of 1 day to 4 weeks, chicks were exposed to continuous white noise in the 2DG experiments. In monaural subjects nucleus angularis and nucleus magnocellularis showed faint 2DG uptake on the side contralateral to the intact ear. In the binaural nucleus laminaris, the asymmetrical and almost mirror\u2010imaged labeling pattern (Lippe, Stewart, and Rubel: <jats:italic>Brain Res. 196<\/jats:italic>:43\u201358, '80) was produced. The superior olive (OS) was strongly labeled on the ipsilateral side, whereas the contralateral OS showed only a slight 2DG uptake at its medial border. The lateral lemniscus and nucleus lemnisci lateralis, pars ventralis (LLv) showed stronger activation on the contralateral side. Both Nissl stains and 2DG patterns provide evidence that nucleus ventralis lemnisci lateralis (VLV) can be subdivided into an anterior (VLVa) and a posterior (VLVp) part. Whereas VLVp is labeled only contralaterally, VLVa is labeled on both sides with similar intensity. Nucleus mesencephalicus lateralis, pars dorsalis (MLD) is strongly labeled throughout contralaterally. The ipsilateral MLD shows a defined ventral portion of high 2DG uptake. Intensity of labeling here is symmetrical to the corresponding area of the contralateral MLD. These symmetrical patterns were related to the tonotopic organization of MLD, which was mapped in intact animals by using tone stimuli. Assuming that symmetrical 2DG uptake in monaural animals indicates excitatory input from both ears (EE\u2010cells), it appears that these EE\u2010cells occupy a sector of each isofrequency plane in MLD. Nucleus ovoidalis (Ov) generally was stronger labeled on the contralateral side. The columnar organization of field L as seen in monaural chicks has already been described (Scheich, <jats:italic>Exp. Brain Res. 51<\/jats:italic>:199\u2013205, '83). In bilaterally deafened chicks, MLD, Ov, and layer L<jats:sub>2<\/jats:sub> of field L showed strong but spatially restricted 2DG accumulation in contrast to absence of labeling in peripheral nuclei.<\/jats:p><jats:p>The 2DG patterns in monaural chicks are likely to reflect excitatory input within the auditory system. In addition they reveal new insights into the functional organization of some of its nuclei. In particular, they support the notion that MLD contains maps of several interaural integration mechanisms similar to field L. Labeling in the auditory system of bilaterally deafened chicks may result from descending projections or from other than auditory inputs.<\/jats:p>","DOI":"10.1002\/cne.902520302","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T20:11:31Z","timestamp":1104610291000},"page":"279-301","source":"Crossref","is-referenced-by-count":64,"title":["Effects of unilateral and bilateral cochlea removal on 2\u2010deoxyglucose patterns in the chick auditory system"],"prefix":"10.1002","volume":"252","author":[{"given":"Peter","family":"Heil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henning","family":"Scheich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,9]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"S238","article-title":"Autoradiographic studies of stimulation\u2010induced changes in rat hippocampal metabolism and blood flow","volume":"3","author":"Ackermann R. F.","year":"1983","journal-title":"J. Cereb. Blood Flow Metab. (Suppl. 1"},{"key":"e_1_2_1_3_1","first-page":"249","article-title":"Tonotopic organizations at higher levels of the auditory pathway","volume":"10","author":"Aitkin L. M.","year":"1976","journal-title":"Int. Rev. Physiol."},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00236295"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01900389"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901940312"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901910310"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1983.49.6.1504"},{"key":"e_1_2_1_9_1","first-page":"800","article-title":"Activation of sexual and aggressive behaviour by androgen implants in the brain of the male ringdove","volume":"7","author":"Barfield R. J.","year":"1967","journal-title":"Am. Zool."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(77)90658-8"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(70)90104-6"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-4328(84)90219-5"},{"key":"e_1_2_1_13_1","unstructured":"Bock W.(1981)Vokalisationen ausgel\u00f6st durch elektrische Stimulationen in Vorderhirn\u2010 Zwischenhirn\u2010 und Mittelhirn\u2010Gebieten bei Perlh\u00fchnern(Numida meleagris). Doctoral thesis Darmstadt."},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00236891"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00614496"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901330410"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1969.tb20444.x"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901200305"},{"key":"e_1_2_1_19_1","first-page":"843","article-title":"Cochlea removal eliminates physiological activity in brain stem auditory nuclei of the chicken","volume":"10","author":"Born D. E.","year":"1984","journal-title":"Soc. Neurosci. Abstr."},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902310403"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1985.tb05438.x"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00238032"},{"key":"e_1_2_1_23_1","first-page":"S170","article-title":"Deoxyglucose uptake in gerbil auditory cortex","volume":"22","author":"Caird D.","year":"1985","journal-title":"Neurosci. Lett. Suppl."},{"key":"e_1_2_1_24_1","doi-asserted-by":"crossref","first-page":"2350","DOI":"10.1523\/JNEUROSCI.03-11-02350.1983","article-title":"The parcellation of the medial geniculate body of the cat defined by the auditory response properties of single neurons","volume":"3","author":"Calford M. B.","year":"1983","journal-title":"J. Neurosci."},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(82)90027-0"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(74)90509-5"},{"key":"e_1_2_1_27_1","unstructured":"Coles R. B.(1977) Physiological and Anatomical Studies of Auditory Units in Midbrain Areas of the Domestic Fowl (Gallus gallus). Thesis Monash University."},{"key":"e_1_2_1_28_1","first-page":"714","article-title":"Functional organization of auditory centres in the midbrain of birds","volume":"45","author":"Coles R. B.","year":"1978","journal-title":"Int. Congr. Ornithol."},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00610398"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(86)91583-0"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1159\/000124324"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(69)90160-7"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902310404"},{"key":"e_1_2_1_34_1","first-page":"343","article-title":"Untersuchungen \u00fcber die vergleichende Anatomie des Gehirns. 5. Das Vorderhirn der V\u00f6gel. Abhandl. der Senckenbergischen Naturforsch","volume":"20","author":"Edinger L.","year":"1903","journal-title":"Gesellsch."},{"key":"e_1_2_1_35_1","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/BF00239410","article-title":"Central localisation of somatic evoked responses in landes goose","volume":"53","author":"Felix B.","year":"1983","journal-title":"Exp. Brain Res."},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901250306"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902320210"},{"key":"e_1_2_1_38_1","first-page":"109","volume-title":"Handbook of Sensory Physiology","author":"Goldberg J. M.","year":"1975"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(84)90702-9"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-4328(84)90190-6"},{"key":"e_1_2_1_41_1","unstructured":"H\u00e4usler U.(1983) Histologische und elektrophysiologische Untersuchungen an einzelnen Neuronen des Nucleus ovoidalis im Zwischenhirn des Staren (Sturnus vulgarisL.).Diplomarbeit Ruhr\u2014Universit\u00e4t Bochum."},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00235869"},{"key":"e_1_2_1_43_1","first-page":"S168","article-title":"2\u2010Deoxyglucose patterns in the auditory system of monaurally and binaurally deafened chicks","volume":"22","author":"Heil P.","year":"1985","journal-title":"Neurosci. Lett. Suppl."},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(81)90074-1"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-4328(82)90091-2"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(82)90045-8"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(67)90055-8"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(68)90078-4"},{"key":"e_1_2_1_49_1","volume-title":"A Stereotaxic Atlas of the Brain of the Pigeon (Columba livia)","author":"Karten H. J.","year":"1967"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901830302"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1114332"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902180205"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1978.41.4.870"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.715444"},{"key":"e_1_2_1_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(66)90091-4"},{"key":"e_1_2_1_56_1","first-page":"487","article-title":"Eine auditorische Periodenanalyse und ihre Bedeutung f\u00fcr die Tonh\u00f6henwahrnehmung. Fortschritte der Akustik: Plenarvortr\u00e4ge und Kurzreferate der 11. Tagung der Deutschen Arbeitsgemeinschaft f\u00fcr Akustik","volume":"85","author":"Langner G.","year":"1985","journal-title":"DAGA"},{"key":"e_1_2_1_57_1","unstructured":"Leibler L.(1975)Ascending Binaural and Monaural Pathways to Mesencephalic and Diencephalic Auditory Nuclei in the Pigeon Columba livia. Doctoral thesis MIT Cambridge MA."},{"key":"e_1_2_1_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)90715-5"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(62)90072-9"},{"key":"e_1_2_1_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1980.tb04643.x"},{"key":"e_1_2_1_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(84)90050-9"},{"key":"e_1_2_1_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(83)90404-4"},{"key":"e_1_2_1_63_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.03-12-02553.1983"},{"key":"e_1_2_1_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00610661"},{"key":"e_1_2_1_65_1","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1159\/000228812","article-title":"Beitr\u00e4ge zur Anatomie und Physiologie des Centralnervensystems der Taube","volume":"3","author":"M\u00fcnzer E.","year":"1898","journal-title":"Mschr Psychiatr. Neurol."},{"key":"e_1_2_1_66_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902450410"},{"key":"e_1_2_1_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901640404"},{"key":"e_1_2_1_68_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901800303"},{"key":"e_1_2_1_69_1","first-page":"195","article-title":"Les ganglions terminaux du nerf acoustique des oiseaux","volume":"6","author":"Ram\u00f3n y Cajal S.","year":"1908","journal-title":"Trab. Inst. Cajal Invest. Biol."},{"key":"e_1_2_1_70_1","first-page":"161","article-title":"Terminaci\u00f3n perif\u00e9rica del nervio ac\u00fastico de la aves","volume":"6","author":"Ram\u00f3n y Cajal S.","year":"1908","journal-title":"Trab. Inst. Cajal Invest. Biol."},{"key":"e_1_2_1_71_1","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1002\/cne.901840308","article-title":"Somatic neurons in the brain stem and neocortex projection to the external nucleus of the inferior colliculus: An anatomical study in the opossum","volume":"184","author":"Robards M. J.","year":"1979","journal-title":"J. Comp. Neurol."},{"key":"e_1_2_1_72_1","first-page":"278","article-title":"\u00dcber die cytoarchitektonische Gliederung des Vorderhirns der V\u00f6gel","volume":"21","author":"Rose M.","year":"1914","journal-title":"J. Psychol. Neurol."},{"key":"e_1_2_1_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901640403"},{"key":"e_1_2_1_74_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902070408"},{"key":"e_1_2_1_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00667105"},{"key":"e_1_2_1_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)91233-0"},{"key":"e_1_2_1_77_1","unstructured":"Scheich H.(1979) Common principles of organization in the central auditory pathway of vertebrates.Verh. Dtsch. Zool. Ges.:155\u2013166."},{"key":"e_1_2_1_78_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237195"},{"key":"e_1_2_1_79_1","first-page":"195","volume-title":"Fortschritte der Akustik 31: Experimental Behavioral Ecology","author":"Scheich H.","year":"1985"},{"key":"e_1_2_1_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00235161"},{"key":"e_1_2_1_81_1","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/978-1-4684-3908-3_38","volume-title":"Neuronal Mechanisms of Hearing","author":"Scheich H.","year":"1981"},{"key":"e_1_2_1_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/293574a0"},{"key":"e_1_2_1_83_1","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/0166-2236(81)90094-1","article-title":"Midbrain vocalization centres in birds","volume":"74","author":"Seller T. J.","year":"1981","journal-title":"Trends Neurosci."},{"key":"e_1_2_1_84_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902280403"},{"key":"e_1_2_1_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(81)90393-0"},{"key":"e_1_2_1_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00238836"},{"key":"e_1_2_1_87_1","first-page":"85","article-title":"The [14C] deoxyglucose method for the quantitative determination of local cerebral glucose consumption","volume":"5","author":"Sokoloff L.","year":"1974","journal-title":"Trans. Am. Soc. Neurochem."},{"key":"e_1_2_1_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902310308"},{"key":"e_1_2_1_89_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.04-07-01787.1984"},{"key":"e_1_2_1_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(84)90557-3"},{"key":"e_1_2_1_91_1","doi-asserted-by":"crossref","first-page":"496","DOI":"10.2183\/pjab.54.496","article-title":"Plastic reorganization of the inferior colliculus of the immature mouse studied by [14C] deoxyglucose method","volume":"54","author":"Taniguchi J.","year":"1978","journal-title":"Proc. Jap. Acad."},{"key":"e_1_2_1_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(84)90140-X"},{"key":"e_1_2_1_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(84)91197-1"},{"key":"e_1_2_1_94_1","first-page":"461","article-title":"Auditory and non\u2010auditory subcortical afferents to the inferior colliculus in the rat","volume":"25","author":"Tokunaga A.","year":"1984","journal-title":"J. Hirnforsch."},{"key":"e_1_2_1_95_1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1121\/1.1911818","article-title":"Stimulus level of dichotically presented tones and cat superior olive s\u2010segmented cell discharge","volume":"46","author":"Tsuchitani C.","year":"1969","journal-title":"J. Acoust. Soc. Am."},{"key":"e_1_2_1_96_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237983"},{"key":"e_1_2_1_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(85)90021-8"},{"key":"e_1_2_1_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)90526-7"},{"key":"e_1_2_1_99_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901810307"}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.902520302","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.902520302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T22:35:08Z","timestamp":1697841308000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.902520302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,10,15]]},"references-count":98,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1986,10,15]]}},"alternative-id":["10.1002\/cne.902520302"],"URL":"https:\/\/doi.org\/10.1002\/cne.902520302","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,10,15]]}}}