{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,27]],"date-time":"2025-11-27T10:07:12Z","timestamp":1764238032949},"reference-count":42,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":6272,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1987,8,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Inbred BALB\/c mice are genetically the same, yet less than half of adults show absent or small corpus callosum. Is this because only a minority has prenatal defects of the sling at the telencephalic midline, or do most fetuses have a defective sling but some are able to form a corpus callosum via some other substrate pathway? This question was addressed by comparing large samples of BALB\/c fetuses at 17, 18, and 19 days after conception with a series of normal C57BL\/6 and hybrid fetuses matched for body size.<\/jats:p><jats:p>At 17 days postconception almost all BALB\/c fetuses show an unusual widening or bulge in the interhemispheric fissure anterior to the hippocampal commissure. Furthermore, formation of the hippocampal commissure is greatly retarded, although it eventually attains a normal size in adult mice. At 17 days, when mice of normal strains all have a corpus callosum at midplane, almost every BALB\/c fetus lacks the structure, but 1 day later 67% of fetuses show delayed formation of this structure and by 19 days all but 7% of fetuses have some callosal axons crossing the midsagittal plane. Many BALB\/c fetuses are able to form a corpus callosum without the benefit of a normal sling. The degree of delay of axon crossing is strongly correlated with the severity of sling defects. An unusually small adult corpus callosum occurs because fetal axons are able to follow unusual pathways and actively compensate for absence of the sling, not because of arrested midline development.<\/jats:p>","DOI":"10.1002\/cne.902620205","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T20:33:58Z","timestamp":1104611638000},"page":"227-241","source":"Crossref","is-referenced-by-count":40,"title":["Defects of the fetal forebrain in mice with hereditary agenesis of the corpus callosum"],"prefix":"10.1002","volume":"262","author":[{"given":"Douglas","family":"Wahlsten","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(84)90305-5"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1985.050.01.105"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902100403"},{"key":"e_1_2_1_5_1","first-page":"68","volume-title":"Onderzoek naar de Vroege Ontwikkeling van de Commissuren in het mediane gebied van bet Telencephalon bij de Witte Muis","author":"Glas P.","year":"1975"},{"key":"e_1_2_1_6_1","first-page":"565","volume-title":"Developmental Biology","author":"Hankin M. H.","year":"1986"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/B978-0-12-052901-8.50019-8","volume-title":"Early Brain Damage","author":"Jeeves M. A.","year":"1984"},{"key":"e_1_2_1_8_1","first-page":"87","article-title":"The embryology of the telencephalic fibre systems in the mouse","volume":"2","author":"K\u00e4llen B.","year":"1954","journal-title":"J. Embryol. Exp. Morphol."},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1523\/JNEUROSCI.05-03-00589.1985","article-title":"How straight do axons grow?","volume":"5","author":"Katz M. J.","year":"1985","journal-title":"J. Neurosci."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(80)90151-7"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.80.19.5936"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(83)90210-9"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902230407"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(86)90159-8"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/91.3.553"},{"key":"e_1_2_1_16_1","first-page":"34","volume-title":"Evolution and Modification of Behavior","author":"Lorenz K.","year":"1966"},{"key":"e_1_2_1_17_1","first-page":"85","article-title":"\u2018Heterosis\u2019 in litter size of chimaeric mice Genet","volume":"46","author":"Mikami H.","year":"1985","journal-title":"Res."},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291700051424"},{"key":"e_1_2_1_19_1","first-page":"320","volume-title":"Statistical Package for the Social Sciences","author":"Nie N. H.","year":"1975"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1007\/978-1-4684-4802-3_2","volume-title":"Organizing Principles of Neural Development","author":"Rakic P.","year":"1984"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901320103"},{"key":"e_1_2_1_22_1","first-page":"1503","article-title":"Role of the subventricular zone in growth and guidance of callosal axons","volume":"12","author":"Schneider B. F.","year":"1986","journal-title":"Soc. Neurosci. Abstr."},{"key":"e_1_2_1_23_1","first-page":"1370","article-title":"Patterns of interhemispheric connections in neocortex of mice with congenital deficiencies of the callosal commissure","volume":"72","author":"Serra\u2010Oller M. M.","year":"1986","journal-title":"Soc. Neurosci. Abstr."},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(79)90252-5"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902100103"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.6844928"},{"key":"e_1_2_1_27_1","first-page":"334","article-title":"The immature astrocyte: Its role during normal CNS axon tract development and its ability to reduce scar formation and promote axonal regeneration when transplanted into the brains of adults","volume":"11","author":"Silver J.","year":"1985","journal-title":"Soc. Neurosci. Abstr."},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901850102"},{"key":"e_1_2_1_29_1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1007\/978-1-349-03645-5_39","volume-title":"Structure and Function of Cerebral Commissures","author":"Stefanko S. Z.","year":"1979"},{"key":"e_1_2_1_30_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.04.030181.001115"},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01262426"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/1831654a0"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(74)90530-7"},{"key":"e_1_2_1_34_1","first-page":"572","article-title":"Hereditary deficiency of corpus callosum in mice: Lack of segregation within a BALB substrain showing incomplete penetrance","volume":"8","author":"Wahlsten D.","year":"1978","journal-title":"Behav. Genet"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(81)90001-8"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(82)90513-3"},{"key":"e_1_2_1_37_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1093\/oxfordjournals.jhered.a109640","article-title":"Mode of inheritance of deficient corpus callosum in mice","volume":"73","author":"Wahlsten D.","year":"1982","journal-title":"J. Hered."},{"key":"e_1_2_1_38_1","first-page":"367","volume-title":"Genetics of the Brain","author":"Wahlsten D.","year":"1982"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(83)90054-8"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(84)90140-8"},{"key":"e_1_2_1_41_1","first-page":"494","article-title":"Structural changes in brains of mice with n genesis of the corpus callosum","volume":"9","author":"Wahlsten D.","year":"1983","journal-title":"Soc. Neurosci. Abstr."},{"key":"e_1_2_1_42_1","first-page":"79","article-title":"Application of a morphological time scale to hereditary differences in prenatal mouse development","volume":"42","author":"Wahlsten D.","year":"1977","journal-title":"J. Embryol. Exp. Morphol."},{"key":"e_1_2_1_43_1","first-page":"133","article-title":"Le processus d\u00e9g\u00e9n\u00e9Yatif au cours du d\u00e9velopment du corps callenx","volume":"74","author":"Zaki W.","year":"1985","journal-title":"Arch. Anat. Microsc. Morphol. Exp."}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.902620205","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.902620205","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T19:31:49Z","timestamp":1697916709000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.902620205"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,8,8]]},"references-count":42,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1987,8,8]]}},"alternative-id":["10.1002\/cne.902620205"],"URL":"https:\/\/doi.org\/10.1002\/cne.902620205","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,8,8]]}}}