{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:17:49Z","timestamp":1760782669547},"reference-count":49,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":4999,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1991,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We have previously shown that two types of cells in the ganglion cell layer of the adult cat retina are immunoreactive for somatostatin (White et al., '90). One of the types was identified by morphological criteria as a wide\u2010field amacrine cell. The other cell type had a large, angular soma that resembled the alpha ganglion cell, but evidence was not available to identify it definitively as a ganglion cell. Both cell types were distributed preferentially in the inferior retina. In this report, we demonstrate that the two types of cell are, indeed, displaced amacrine cells and alpha ganglion cells. First, when retrograde tracers were injected into central visual targets, the immunoreactive large cells but not the displaced amacrine cells were found to be labeled. Second, after unilateral section of the optic nerve, the immunoreactive large cells disappeared from the retina on the lesioned side, but the displaced amacrine cells occurred in the same numbers in both retinae. In the periphery, the large cells ranged in diameter from 33 to 47 \u03bcm, comparable only to alpha ganglion cells (Boycott and W\u00e4ssle, '74). An antiserum to parvalbumin was used to visualize the dendrites (R\u00f6hrenbeck and W\u00e4ssle, '88) of somatostatin\u2010immunoreactive large cells. Based on dendritic stratification within the inner plexiform layer (Famiglietti and Kolb, '76), the somatostatin\u2010immunoreactive large cells were found to include both on\u2010center cells and off\u2010center cells, but were predominantly of the off\u2010center type. Within a local region, they were found to be arrayed with greater regularity than the overall population of alpha ganglion cells. These results indicate that alpha ganglion cells of the cat retina can be subdivided on the basis of their immunoreactive staining for somatostatin and suggest that the diversity of ganglion cells in the cat retina may be greater than has been recognized on the basis of morphological criteria alone.<\/jats:p>","DOI":"10.1002\/cne.903040102","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T19:45:45Z","timestamp":1104608745000},"page":"1-13","source":"Crossref","is-referenced-by-count":29,"title":["Subgroup of alpha ganglion cells in the adult cat retina is immunoreactive for somatostatin"],"prefix":"10.1002","volume":"304","author":[{"given":"C. A.","family":"White","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. M.","family":"Chalupa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523800005915"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1974.sp010616"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/327155a0"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902690109"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00495150"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(89)90475-8"},{"key":"e_1_2_1_8_1","first-page":"111","article-title":"Osmium tetroxide\u2010picric acid: A new fixation technique in electron microscopy","volume":"4","author":"De Martino C.","year":"1972","journal-title":"J. of Submicroscopic Cytol."},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902660208"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1523\/JNEUROSCI.08-01-00119.1988","article-title":"Ganglion cells in the turtle retina contain the neuropeptide LANT\u20106","volume":"8","author":"Eldred W. D.","year":"1988","journal-title":"J. Neurosci."},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0301-0082(86)90012-2"},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1126\/science.959847","article-title":"Structural basis for On\u2010 and Off\u2010center responses in retinal ganglion cells","volume":"1994","author":"Famiglietti E. V.","year":"1976","journal-title":"Science"},{"key":"e_1_2_1_13_1","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1523\/JNEUROSCI.03-06-01308.1983","article-title":"Somatostatin\u2010like immunoreactivity characterizes neurons of the nucleus reticularis thalami in the cat and monkey","volume":"3","author":"Graybiel A. M.","year":"1983","journal-title":"J. Neurosci."},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00235279"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902750309"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/283087a0"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523800003370"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0952523800001024"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902480102"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(73)90226-4"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(88)90120-4"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902280410"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)91031-4"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1978.41.2.472"},{"key":"e_1_2_1_25_1","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1523\/JNEUROSCI.03-06-01322.1983","article-title":"Coexistence of glutamic acid decarboxylase\u2010 and somatostatin\u2010like immunoreactivity in neurons of the feline nucleus reticularis thalami","volume":"3","author":"Oertel W. H.","year":"1983","journal-title":"J. Neurosci."},{"key":"e_1_2_1_26_1","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1073\/pnas.82.18.6335","article-title":"Morphology and distribution of tyrosine hydroxylase\u2010like immunoreactive neurons in the cat retina","volume":"82","author":"Oyster C. W.","year":"1985","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1981.0030"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1987.0040"},{"key":"e_1_2_1_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-74149-4_37"},{"key":"e_1_2_1_30_1","first-page":"13","article-title":"Immunocytochemical staining of cat retinal ganglion cells using antibodies against parvalbumin","volume":"42","author":"R\u00f6hrenbeck J.","year":"1988","journal-title":"Euro. J. Neurosci."},{"key":"e_1_2_1_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(87)90508-8"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902660212"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(88)90284-9"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/216173a0"},{"key":"e_1_2_1_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902580108"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1986.tb02829.x"},{"key":"e_1_2_1_37_1","first-page":"585","article-title":"The naso\u2010temporal division of the cat's retina","volume":"126","author":"Stone J.","year":"1966","journal-title":"J. Comp. Neurol."},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4684-4433-9"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902430311"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.07-12-04115.1987"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902610202"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.08-09-03383.1988"},{"key":"e_1_2_1_43_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1978.0026"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901590308"},{"key":"e_1_2_1_45_1","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1981.0032"},{"key":"e_1_2_1_46_1","first-page":"494","article-title":"Somatostatin\u2010like immunoreactivity (SRIF\u2010I) in ganglion and other cells of the developing cat retina","volume":"15","author":"White C. A.","year":"1989","journal-title":"Soc. Neurosci. Abst."},{"key":"e_1_2_1_47_1","first-page":"466","article-title":"A subgroup of alpha ganglion cells in the adult cat retina expresses somatostatin\u2010like immunoreactivity (SRIF\u2010IR)","volume":"16","author":"White C. A.","year":"1990","journal-title":"Soc. Neurosci. Abst."},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902930111"},{"key":"e_1_2_1_49_1","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/cne.902800308","article-title":"Amacrine and ganglion cells with corticotropin\u2010releasing\u2010factor\u2010like immunoreactivity in the turtle retina","volume":"280","author":"Williamsom D. E.","year":"1989","journal-title":"J. Comp. Neurol."},{"key":"e_1_2_1_50_1","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1523\/JNEUROSCI.10-02-00383.1990","article-title":"The physiology of somatostatin in the rabbit retina","volume":"10","author":"Zalutsky R. A.","year":"1990","journal-title":"J. Neurosci."}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.903040102","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.903040102","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,22]],"date-time":"2023-10-22T21:07:32Z","timestamp":1698008852000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.903040102"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,2]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1991,2]]}},"alternative-id":["10.1002\/cne.903040102"],"URL":"https:\/\/doi.org\/10.1002\/cne.903040102","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,2]]}}}