{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T13:09:32Z","timestamp":1791464972903,"version":"4.3.4"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,10,9]],"date-time":"2004-10-09T00:00:00Z","timestamp":1097280000000},"content-version":"vor","delay-in-days":4309,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J of Comparative Neurology"],"published-print":{"date-parts":[[1992,12,22]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The central retina in albino mammals is poorly developed. There is a general reduction in ganglion cell density compared with the normal animal, and there are irregularities in the center to periphery gradient in ganglion cell density. It is not known whether, and if so to what extent, this abnormality is associated with deficits in other retinal layers.<\/jats:p><jats:p>In this study the distribution of cells in the ganglion cell layer has been determined in horizontally sectioned eyes from pigmented and albino ferrets. This was undertaken to define the location of the region of highest cell density and the relative cell gradients around it. Detailed counts and measurements were then undertaken to determine the cell density within, and thickness of, the inner and the outer nuclear layers in these animals.<\/jats:p><jats:p>All the albino animals had an abnormal distribution of cells in the ganglion cell layer in the central retina when compared with pigmented animals. The extent of this abnormality was variable. No differences between pigmented and albino animals could be found in the packing density of cells within the inner or the outer nuclear layer. However, in the pigmented animals there was a clear increase in the thickness of these layers associated with the region of highest density in the ganglion cell layer. This feature was absent in the albino animals, where the gradient in layer thickness was less marked and frequently contained irregularities. These abnormalities were most obvious in the outer nuclear layer. \u00a9 1992 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.903260410","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T08:36:12Z","timestamp":1104568572000},"page":"637-644","source":"Crossref","is-referenced-by-count":26,"title":["Translaminar deficits in the retinae of albinos"],"prefix":"10.1002","volume":"326","author":[{"given":"Glen","family":"Jeffery","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Kinsella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/cne.903050211","article-title":"Evaluation of the influence of optic stalk melanin on the chiasmatic pathways in the developing rodent visual system","volume":"305","author":"Collelo R. J.","year":"1991","journal-title":"J. Comp. Neurol."},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901870205"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901910306"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1159\/000118764","article-title":"The morphology, number, distribution and central projections of class I retinal ganglion cells in albino and hooded rats","volume":"23","author":"Dreher B.","year":"1985","journal-title":"Brain Behav. Evol."},{"key":"e_1_2_1_6_1","volume-title":"Systems of Ophthalmology","author":"Duke\u2010Elder S.","year":"1964"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/BF02080368","article-title":"Zur Anatomie des menschlichen Albinoages","volume":"84","author":"Elschig A.","year":"1913","journal-title":"Graefe's Arch. Ophthalmol."},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(77)90314-6"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0006-8993(69)90213-3","article-title":"An abnormal retinogeniculate projection in Siamese cats","volume":"14","author":"Guillery R. W.","year":"1969","journal-title":"Brain Res."},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0166-2236(86)90115-3"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902260203"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(89)90246-7"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-3806(84)90079-8"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(85)90198-2"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-85986-1_14"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1523\/JNEUROSCI.02-08-01024.1982","article-title":"Morphology and distribution of retinal ganglion cells projecting to different layers of the dorsal lateral geniculate nucleus in normal and Siamese cats","volume":"2","author":"Leventhal A. G.","year":"1982","journal-title":"J. Neurosci."},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.149.3691.1506"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(87)90108-4"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902550105"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901800407"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901800409"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901800408"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/13.1.46"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.05-03-00741.1985"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903070309"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902550202"},{"key":"e_1_2_1_27_1","first-page":"193","article-title":"The life history of retinal cells","volume":"81","author":"Young R. W.","year":"1983","journal-title":"Trans. Am. Ophthalmol. Soc."}],"container-title":["Journal of Comparative Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fcne.903260410","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/cne.903260410","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,23]],"date-time":"2023-10-23T11:46:55Z","timestamp":1698061615000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/cne.903260410"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,12,22]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1992,12,22]]}},"alternative-id":["10.1002\/cne.903260410"],"URL":"https:\/\/doi.org\/10.1002\/cne.903260410","archive":["Portico"],"relation":{},"ISSN":["0021-9967","1096-9861"],"issn-type":[{"value":"0021-9967","type":"print"},{"value":"1096-9861","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,12,22]]}}}