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Ninety\u2010five percent of the synaptic contacts were symmetric in configuration and the remaining 5% were asymmetric. Axosomatic contacts comprised 6% of all enkephalin\u2010immunoreactive junctions and were distributed equally in all parts of the nucleus. Most (76%) synaptic terminals contacted dendrites but they contacted proportionally fewer dendrites in the shell (71%) than in the core (78%). Moreover, enkephalin\u2010immunoreactive synaptic boutons in the shell (19%) and caudal enkephalin\u2010rich areas (17%) of the core contacted twice as many spines than in the remaining parts of the core (8.5%). In the core, long pallidum\u2010like dendrites were occasionally found ensheathed in enkephalin\u2010immunoreactive terminal boutons.<\/jats:p><jats:p>We conclude that the differential arrangement of enkephalinergic contacts in the shell and core could have important functional consequences, especially when considered in relation to other known morphological and neurochemical differences between these regions. \u00a9 1993 Wiley\u2010Liss, Inc.<\/jats:p>","DOI":"10.1002\/cne.903320207","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T08:49:30Z","timestamp":1104569370000},"page":"224-236","source":"Crossref","is-referenced-by-count":35,"title":["Ultrastructural characteristics of enkephalin\u2010immunoreactive boutons and their postsynaptic targets in the shell and core of the nucleus accumbens of the rat"],"prefix":"10.1002","volume":"332","author":[{"given":"G. 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